Oncostatin M-induced activation of stress-activated MAP kinases depends on tyrosine 861 in the OSM receptor and requires Jak1 but not Src kinases. [electronic resource]
Producer: 20060302Description: 50-61 p. digitalISSN:- 0898-6568
- Animals
- Cell Line
- Cell Proliferation -- drug effects
- Cytokines -- pharmacology
- Early Growth Response Protein 1 -- drug effects
- Enzyme Activation -- drug effects
- Humans
- Imidazoles -- pharmacology
- JNK Mitogen-Activated Protein Kinases -- drug effects
- Janus Kinase 1
- MAP Kinase Signaling System -- drug effects
- Mice
- Mitogen-Activated Protein Kinase 1 -- drug effects
- Mitogen-Activated Protein Kinase 3 -- drug effects
- Oncostatin M
- Phosphorylation
- Protein-Tyrosine Kinases -- drug effects
- Pyridines -- pharmacology
- Receptors, Cytokine -- drug effects
- Receptors, Oncostatin M
- Tyrosine -- metabolism
- p38 Mitogen-Activated Protein Kinases -- drug effects
- src-Family Kinases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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