Induction of antigen-specific Th1-biased immune responses by plasmid DNA in schistosoma-infected mice with a preexistent dominant Th2 immune profile. [electronic resource]
Producer: 20010517Description: 1169-76 p. digitalISSN:- 0006-291X
- Animals
- Antigens, Helminth -- immunology
- Cells, Cultured
- DNA -- administration & dosage
- Epitopes -- immunology
- Female
- Immunity, Cellular -- drug effects
- Immunoglobulin E -- blood
- Immunoglobulin G -- blood
- Injections, Intradermal
- Interferon-gamma -- metabolism
- Interleukin-4 -- metabolism
- Mice
- Mice, Inbred BALB C
- Plasmids -- administration & dosage
- Schistosoma mansoni -- immunology
- Schistosomiasis -- blood
- Spleen -- cytology
- T-Lymphocytes, Helper-Inducer -- immunology
- Th1 Cells -- immunology
- Th2 Cells -- immunology
- Vaccines, DNA -- administration & dosage
- beta-Galactosidase -- biosynthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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