Hypoxia-induced production of 12-hydroxyeicosanoids in the corneal epithelium: involvement of a cytochrome P-4504B1 isoform. [electronic resource]
Producer: 19990615Description: 1611-9 p. digitalISSN:- 0022-3565
- 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid -- biosynthesis
- Animals
- Arachidonic Acid -- metabolism
- Aryl Hydrocarbon Hydroxylases
- Base Sequence
- Cell Hypoxia -- physiology
- Clofibrate -- pharmacology
- Cloning, Molecular
- Cytochrome P-450 CYP4A
- Cytochrome P-450 Enzyme System -- genetics
- DNA, Complementary
- Epithelium, Corneal -- drug effects
- Female
- Isoenzymes -- genetics
- Lung -- enzymology
- Male
- Mixed Function Oxygenases -- genetics
- Molecular Sequence Data
- Organ Culture Techniques
- Phenobarbital -- pharmacology
- Polymerase Chain Reaction
- RNA, Messenger -- metabolism
- Rabbits
- Sequence Alignment
- Sequence Homology, Nucleic Acid
- Stereoisomerism
- Transcription, Genetic
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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