Dickkopf-3 regulates prostate epithelial cell acinar morphogenesis and prostate cancer cell invasion by limiting TGF-β-dependent activation of matrix metalloproteases. [electronic resource]
Producer: 20160615Description: 18-29 p. digitalISSN:- 1460-2180
- Acinar Cells -- metabolism
- Adaptor Proteins, Signal Transducing
- Cell Line, Tumor
- Chemokines
- Enzyme Activation
- Epithelial Cells -- metabolism
- Gene Silencing
- Humans
- Intercellular Signaling Peptides and Proteins -- genetics
- Male
- Matrix Metalloproteinase 2 -- biosynthesis
- Matrix Metalloproteinase 9 -- biosynthesis
- Morphogenesis
- Neoplasm Invasiveness
- Prostatic Neoplasms -- enzymology
- Protein Structure, Tertiary
- Signal Transduction
- Transforming Growth Factor beta -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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