Urothelial carcinogenesis in the urinary bladder of male rats treated with muraglitazar, a PPAR alpha/gamma agonist: Evidence for urolithiasis as the inciting event in the mode of action. [electronic resource]
Producer: 20070123Description: 903-20 p. digitalISSN:- 0192-6233
- Animals
- Antimetabolites
- Apoptosis -- drug effects
- Area Under Curve
- Bromodeoxyuridine
- Calcium -- urine
- Carcinogens
- Cell Proliferation -- drug effects
- Citrates -- urine
- Electrolytes -- urine
- Glycine -- analogs & derivatives
- Hydrogen-Ion Concentration
- Immunohistochemistry
- Male
- Microscopy, Electron, Scanning
- Organ Size
- Oxalates -- urine
- Oxazoles -- pharmacokinetics
- PPAR alpha -- agonists
- PPAR gamma -- agonists
- Phosphates -- urine
- Proteinuria -- chemically induced
- Rats
- Rats, Sprague-Dawley
- Spectrometry, X-Ray Emission
- Urinary Bladder Neoplasms -- chemically induced
- Urolithiasis -- chemically induced
- Urothelium -- pathology
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Publication Type: Journal Article
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