Pharmacokinetics and QT interval pharmacodynamics of oral haloperidol in poor and extensive metabolizers of CYP2D6. [electronic resource]
Producer: 20040107Description: 105-13 p. digitalISSN:- 1470-269X
- Adult
- Alleles
- Antipsychotic Agents -- adverse effects
- Area Under Curve
- Cross-Over Studies
- Cytochrome P-450 CYP2D6 -- genetics
- DNA Primers
- Double-Blind Method
- Electrocardiography -- drug effects
- Female
- Genotype
- Half-Life
- Haloperidol -- adverse effects
- Heart Rate -- drug effects
- Humans
- Male
- Reverse Transcriptase Polymerase Chain Reaction
- Sex Characteristics
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Publication Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, U.S. Gov't, P.H.S.
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