14-3-3sigma and p21 synergize to determine DNA damage response following Chk2 inhibition. [electronic resource]
Producer: 20091020Description: 2238-46 p. digitalISSN:- 1551-4005
- 14-3-3 Proteins
- Antibiotics, Antineoplastic -- pharmacology
- Ataxia Telangiectasia Mutated Proteins
- Biomarkers, Tumor -- genetics
- Cell Cycle Proteins -- metabolism
- Cell Line, Tumor
- Checkpoint Kinase 2
- Cyclin-Dependent Kinase Inhibitor p21 -- genetics
- DNA Damage
- DNA Repair
- DNA-Binding Proteins -- metabolism
- Doxorubicin -- pharmacology
- Exonucleases -- genetics
- Exoribonucleases
- G2 Phase
- Gene Knockdown Techniques
- Humans
- Neoplasm Proteins -- genetics
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- RNA Interference
- Tumor Suppressor Protein p53 -- metabolism
- Tumor Suppressor Proteins -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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