Ajoene, an experimental anti-leukemic drug: mechanism of cell death. [electronic resource]
Producer: 20020312Description: 74-83 p. digitalISSN:- 0887-6924
- Amino Acid Chloromethyl Ketones -- pharmacology
- Antineoplastic Agents, Phytogenic -- antagonists & inhibitors
- Apoptosis -- drug effects
- Caspase 3
- Caspase 8
- Caspase 9
- Caspases -- metabolism
- Cysteine Proteinase Inhibitors -- pharmacology
- Cytochrome c Group -- analysis
- DNA Fragmentation -- drug effects
- DNA, Neoplasm -- drug effects
- Disulfides -- antagonists & inhibitors
- Enzyme Activation -- drug effects
- Enzyme Precursors -- metabolism
- Fas Ligand Protein
- Gene Expression Regulation, Leukemic -- drug effects
- HL-60 Cells -- drug effects
- Humans
- Intracellular Membranes -- drug effects
- Jurkat Cells -- drug effects
- Membrane Glycoproteins -- physiology
- Membrane Potentials -- drug effects
- Mitochondria -- drug effects
- NF-kappa B -- metabolism
- Neoplasm Proteins -- antagonists & inhibitors
- Oxidative Stress
- Permeability -- drug effects
- Plant Extracts -- antagonists & inhibitors
- Proto-Oncogene Proteins c-bcl-2 -- biosynthesis
- Reactive Oxygen Species
- Sulfoxides
- bcl-X Protein
- fas Receptor -- biosynthesis
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Publication Type: Journal Article
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