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Evaluation of histone deacetylases as drug targets in Huntington's disease models. Study of HDACs in brain tissues from R6/2 and CAG140 knock-in HD mouse models and human patients and in a neuronal HD cell model. [electronic resource] by
- Quinti, Luisa
- Chopra, Vanita
- Rotili, Dante
- Valente, Sergio
- Amore, Allison
- Franci, Gianluigi
- Meade, Sarah
- Valenza, Marta
- Altucci, Lucia
- Maxwell, Michele M
- Cattaneo, Elena
- Hersch, Steven
- Mai, Antonello
- Kazantsev, Aleksey
Producer: 20101019
In:
PLoS currents vol. 2
Availability: No items available.
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A brain-permeable small molecule reduces neuronal cholesterol by inhibiting activity of sirtuin 2 deacetylase. [electronic resource] by
- Taylor, David M
- Balabadra, Uma
- Xiang, Zhongmin
- Woodman, Ben
- Meade, Sarah
- Amore, Allison
- Maxwell, Michele M
- Reeves, Steven
- Bates, Gillian P
- Luthi-Carter, Ruth
- Lowden, Philip A S
- Kazantsev, Aleksey G
Producer: 20120312
In:
ACS chemical biology vol. 6
Availability: No items available.
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Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease. [electronic resource] by
- Outeiro, Tiago Fleming
- Kontopoulos, Eirene
- Altmann, Stephen M
- Kufareva, Irina
- Strathearn, Katherine E
- Amore, Allison M
- Volk, Catherine B
- Maxwell, Michele M
- Rochet, Jean-Christophe
- McLean, Pamela J
- Young, Anne B
- Abagyan, Ruben
- Feany, Mel B
- Hyman, Bradley T
- Kazantsev, Aleksey G
Producer: 20070813
In:
Science (New York, N.Y.) vol. 317
Availability: No items available.
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SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis. [electronic resource] by
- Luthi-Carter, Ruth
- Taylor, David M
- Pallos, Judit
- Lambert, Emmanuel
- Amore, Allison
- Parker, Alex
- Moffitt, Hilary
- Smith, Donna L
- Runne, Heike
- Gokce, Ozgun
- Kuhn, Alexandre
- Xiang, Zhongmin
- Maxwell, Michele M
- Reeves, Steven A
- Bates, Gillian P
- Neri, Christian
- Thompson, Leslie M
- Marsh, J Lawrence
- Kazantsev, Aleksey G
Producer: 20100602
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 107
Availability: No items available.
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