The effects of inhibiting cytochrome P450 3A, p-glycoprotein, and gastric acid secretion on the oral bioavailability of methadone in dogs. [electronic resource]
Producer: 20051201Description: 461-6 p. digitalISSN:- 0140-7783
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- drug effects
- Administration, Oral
- Animals
- Area Under Curve
- Biological Availability
- Cross-Over Studies
- Cytochrome P-450 CYP3A -- drug effects
- Cytochrome P-450 CYP3A Inhibitors
- Dogs -- metabolism
- Enzyme Inhibitors -- administration & dosage
- Female
- Gastric Acid -- metabolism
- Injections, Intravenous -- veterinary
- Ketoconazole -- administration & dosage
- Male
- Methadone -- administration & dosage
- Omeprazole -- administration & dosage
- Proton Pump Inhibitors
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Publication Type: Journal Article
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