Mitochondrial oxidative stress plays a critical role in the cardiotoxicity of sunitinib: Running title: Sunitinib and oxidative stress in hearts. [electronic resource]
Producer: 20200514Description: 152281 p. digitalISSN:- 1879-3185
- Animals
- Antineoplastic Agents -- toxicity
- Apoptosis -- drug effects
- Caspase 3 -- metabolism
- Cell Line
- Citrate (si)-Synthase -- metabolism
- DNA Fragmentation -- drug effects
- Electron Transport -- drug effects
- Enzyme Activation -- drug effects
- Heart Diseases -- chemically induced
- Humans
- Membrane Potential, Mitochondrial -- drug effects
- Mice
- Mice, Inbred C57BL
- Mitochondria, Heart -- drug effects
- Oxidative Stress -- drug effects
- Sunitinib -- toxicity
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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