Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampus. [electronic resource]
Producer: 20201029Description: 7322 p. digitalISSN:- 2045-2322
- Adaptor Proteins, Signal Transducing -- metabolism
- Aged
- Alzheimer Disease -- pathology
- Animals
- Axin Protein -- metabolism
- Catechin -- analogs & derivatives
- Chromosomes, Human, Pair 21 -- genetics
- Disease Models, Animal
- Down Syndrome -- genetics
- Down-Regulation -- drug effects
- Female
- HEK293 Cells
- HeLa Cells
- Hippocampus -- pathology
- Humans
- Male
- Mice
- Middle Aged
- Protein Serine-Threonine Kinases -- genetics
- Protein-Tyrosine Kinases -- genetics
- RNA-Seq
- Wnt Signaling Pathway -- drug effects
- Dyrk Kinases
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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