IG20, in contrast to DENN-SV, (MADD splice variants) suppresses tumor cell survival, and enhances their susceptibility to apoptosis and cancer drugs. [electronic resource]
Producer: 20040310Description: 1076-87 p. digitalISSN:- 0950-9232
- Alternative Splicing
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Cell Division
- Cell Line, Tumor
- Cell Survival -- drug effects
- Death Domain Receptor Signaling Adaptor Proteins
- Gene Expression Regulation
- Genetic Variation
- Guanine Nucleotide Exchange Factors -- genetics
- HeLa Cells
- Humans
- I-kappa B Proteins -- genetics
- NF-kappa B -- metabolism
- Transfection
- Tumor Necrosis Factor-alpha -- pharmacology
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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