Heterocyclization of Thiophenes Derived from Estrone Followed by Cytotoxic, HTRF Kinase and Pim-1 Kinase Evaluations. [electronic resource]
Producer: 20190717Description: 1711-1728 p. digitalISSN:- 1875-5992
- Antineoplastic Agents -- chemical synthesis
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Dose-Response Relationship, Drug
- Drug Screening Assays, Antitumor
- Humans
- Molecular Structure
- Protein Kinase Inhibitors -- chemical synthesis
- Protein-Tyrosine Kinases -- antagonists & inhibitors
- Proto-Oncogene Proteins c-pim-1 -- antagonists & inhibitors
- Structure-Activity Relationship
- Thiophenes -- chemical synthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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