Aberrant splicing of the tumor suppressor CYLD promotes the development of chronic lymphocytic leukemia via sustained NF-κB signaling. [electronic resource]
Producer: 20181211Description: 72-82 p. digitalISSN:- 1476-5551
- Animals
- B-Lymphocytes -- metabolism
- CD5 Antigens -- genetics
- Cell Proliferation -- genetics
- Cell Survival -- genetics
- Deubiquitinating Enzyme CYLD -- genetics
- Genes, Tumor Suppressor -- physiology
- Humans
- Leukemia, Lymphocytic, Chronic, B-Cell -- genetics
- Mice
- NF-kappa B -- genetics
- RNA Splicing -- genetics
- Signal Transduction -- genetics
- Ubiquitination -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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