The ethyl pyruvate analogues, diethyl oxaloproprionate, 2-acetamidoacrylate, and methyl-2-acetamidoacrylate, exhibit anti-inflammatory properties in vivo and/or in vitro. [electronic resource]
Producer: 20051220Description: 1579-92 p. digitalISSN:- 0006-2952
- Acrylates -- chemistry
- Alanine -- analogs & derivatives
- Animals
- Anti-Inflammatory Agents -- chemistry
- Cell Line
- Drug Evaluation, Preclinical
- Esters -- chemistry
- Glutathione -- metabolism
- Humans
- Inflammation -- chemically induced
- Lipid Peroxidation -- drug effects
- Lipopolysaccharides -- pharmacology
- Male
- Mice
- Mice, Inbred C57BL
- Molecular Structure
- NF-kappa B -- metabolism
- Nitric Oxide -- metabolism
- Propionates
- Tumor Necrosis Factor-alpha -- metabolism
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Publication Type: Journal Article
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