Subchronic studies in Sprague-Dawley rats to investigate mechanisms of MTBE-induced Leydig cell cancer. [electronic resource]
Producer: 20030925Description: 31-42 p. digitalISSN:- 1096-6080
- Administration, Inhalation
- Animals
- Aromatase -- metabolism
- Carcinogens -- adverse effects
- Corticosterone -- metabolism
- Cytochrome P-450 Enzyme System -- metabolism
- Estradiol -- metabolism
- Gonadotropins -- metabolism
- Leydig Cell Tumor -- chemically induced
- Luteinizing Hormone -- metabolism
- Male
- Methyl Ethers -- adverse effects
- Orchiectomy
- Organ Size -- drug effects
- Peroxisomes -- physiology
- Pituitary Hormones -- metabolism
- Rats
- Rats, Sprague-Dawley
- Solvents -- toxicity
- Testosterone -- blood
- Toxicity Tests, Chronic
- Tumor Cells, Cultured
- Weight Gain -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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