Pharmacokinetic-pharmacodynamic modeling of apratastat: a population-based approach. [electronic resource]
Producer: 20110714Description: 472-81 p. digitalISSN:- 1552-4604
- Adolescent
- Adult
- Dose-Response Relationship, Drug
- Double-Blind Method
- Endotoxins -- pharmacology
- Humans
- Lipopolysaccharides -- pharmacology
- Male
- Matrix Metalloproteinase Inhibitors
- Matrix Metalloproteinases -- metabolism
- Middle Aged
- Models, Biological
- Morpholines -- administration & dosage
- Placebos
- Tumor Necrosis Factor-alpha -- antagonists & inhibitors
- Young Adult
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Publication Type: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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