Monoclonal antibody against macrophage colony-stimulating factor suppresses circulating monocytes and tissue macrophage function but does not alter cell infiltration/activation in cutaneous lesions or clinical outcomes in patients with cutaneous lupus erythematosus. [electronic resource]
Producer: 20160608Description: 258-70 p. digitalISSN:- 1365-2249
- Administration, Intravenous
- Adult
- Aged
- Antibodies, Monoclonal -- administration & dosage
- Aspartate Aminotransferases -- urine
- Collagen -- urine
- Creatine Kinase -- urine
- Double-Blind Method
- Female
- Histiocytes -- drug effects
- Humans
- Immunohistochemistry
- Immunotherapy
- Lipopolysaccharide Receptors -- immunology
- Lupus Erythematosus, Cutaneous -- drug therapy
- Macrophage Colony-Stimulating Factor -- immunology
- Macrophages -- immunology
- Male
- Middle Aged
- Monocytes -- immunology
- Receptors, IgG -- immunology
- Severity of Illness Index
- Skin -- drug effects
- Young Adult
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Publication Type: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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