Synthesis, dihydrofolate reductase inhibition, antitumor testing, and molecular modeling study of some new 4(3H)-quinazolinone analogs. [electronic resource]
Producer: 20070202Description: 8608-21 p. digitalISSN:- 0968-0896
- Animals
- Antineoplastic Agents -- chemical synthesis
- Breast Neoplasms -- drug therapy
- Cattle
- Cell Proliferation -- drug effects
- Enzyme Inhibitors -- chemical synthesis
- Folic Acid Antagonists -- chemical synthesis
- Humans
- Liver -- enzymology
- Lung Neoplasms -- drug therapy
- Methotrexate -- pharmacology
- Models, Molecular
- Molecular Structure
- Quinazolinones -- chemical synthesis
- Structure-Activity Relationship
- Tetrahydrofolate Dehydrogenase -- chemistry
- Tumor Cells, Cultured -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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