Spirohydantoins and 1,2,4-triazole-3-carboxamide derivatives as inhibitors of histone deacetylase: Design, synthesis, and biological evaluation. [electronic resource]
Producer: 20180322Description: 79-92 p. digitalISSN:- 1768-3254
- Antineoplastic Agents -- chemical synthesis
- Cell Proliferation -- drug effects
- Crystallography, X-Ray
- Dose-Response Relationship, Drug
- Drug Design
- Drug Screening Assays, Antitumor
- Hep G2 Cells
- Histone Deacetylase Inhibitors -- chemical synthesis
- Histone Deacetylases -- metabolism
- Humans
- MCF-7 Cells
- Models, Molecular
- Molecular Structure
- Polymerization -- drug effects
- Structure-Activity Relationship
- Triazoles -- chemical synthesis
- Tubulin -- metabolism
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Publication Type: Journal Article
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