Results
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1.
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Cardiovascular effects of torcetrapib in conscious and pentobarbital-anesthetized dogs. [electronic resource] by
- Polakowski, James S
- King, Andrew J
- Campbell, Thomas J
- Nelson, Richard A
- Preusser, Lee C
- Kempf-Grote, Anita J
- Marsh, Kennan C
- Gintant, Gary A
- Cox, Bryan F
- Mittelstadt, Scott W
Producer: 20100426
In:
Journal of cardiovascular pharmacology vol. 54
Availability: No items available.
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2.
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A-366833: a novel nicotinonitrile-substituted 3,6-diazabicyclo[3.2.0]-heptane alpha4beta2 nicotinic acetylcholine receptor selective agonist: Synthesis, analgesic efficacy and tolerability profile in animal models. [electronic resource] by
- Ji, Jianguo
- Bunnelle, William H
- Anderson, David J
- Faltynek, Connie
- Dyhring, Tino
- Ahring, Philip K
- Rueter, Lynne E
- Curzon, Peter
- Buckley, Michael J
- Marsh, Kennan C
- Kempf-Grote, Anita
- Meyer, Michael D
Producer: 20071106
In:
Biochemical pharmacology vol. 74
Availability: No items available.
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3.
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Discovery and structure-activity relationships of piperidinone- and piperidine-constrained phenethylamines as novel, potent, and selective dipeptidyl peptidase IV inhibitors. [electronic resource] by
- Pei, Zhonghua
- Li, Xiaofeng
- von Geldern, Thomas W
- Longenecker, Kenton
- Pireh, Daisy
- Stewart, Kent D
- Backes, Bradley J
- Lai, Chunqiu
- Lubben, Thomas H
- Ballaron, Stephen J
- Beno, David W A
- Kempf-Grote, Anita J
- Sham, Hing L
- Trevillyan, James M
Producer: 20070618
In:
Journal of medicinal chemistry vol. 50
Availability: No items available.
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4.
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Structure-based characterization and optimization of novel hydrophobic binding interactions in a series of pyrrolidine influenza neuraminidase inhibitors. [electronic resource] by
- Maring, Clarence J
- Stoll, Vincent S
- Zhao, Chen
- Sun, Minghua
- Krueger, Allan C
- Stewart, Kent D
- Madigan, Darold L
- Kati, Warren M
- Xu, Yibo
- Carrick, Robert J
- Montgomery, Debra A
- Kempf-Grote, Anita
- Marsh, Kennan C
- Molla, Akhteruzzaman
- Steffy, Kevin R
- Sham, Hing L
- Laver, W Graeme
- Gu, Yu-gui
- Kempf, Dale J
- Kohlbrenner, William E
Producer: 20050706
In:
Journal of medicinal chemistry vol. 48
Availability: No items available.
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5.
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Pyrrolidine-constrained phenethylamines: The design of potent, selective, and pharmacologically efficacious dipeptidyl peptidase IV (DPP4) inhibitors from a lead-like screening hit. [electronic resource] by
- Backes, Bradley J
- Longenecker, Kenton
- Hamilton, Gregory L
- Stewart, Kent
- Lai, Chunqiu
- Kopecka, Hana
- von Geldern, Thomas W
- Madar, David J
- Pei, Zhonghua
- Lubben, Thomas H
- Zinker, Bradley A
- Tian, Zhenping
- Ballaron, Stephen J
- Stashko, Michael A
- Mika, Amanda K
- Beno, David W A
- Kempf-Grote, Anita J
- Black-Schaefer, Candace
- Sham, Hing L
- Trevillyan, James M
Producer: 20070725
In:
Bioorganic & medicinal chemistry letters vol. 17
Availability: No items available.
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6.
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Discovery of ((4R,5S)-5-amino-4-(2,4,5- trifluorophenyl)cyclohex-1-enyl)-(3- (trifluoromethyl)-5,6-dihydro- [1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone (ABT-341), a highly potent, selective, orally efficacious, and safe dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes. [electronic resource] by
- Pei, Zhonghua
- Li, Xiaofeng
- von Geldern, Thomas W
- Madar, David J
- Longenecker, Kenton
- Yong, Hong
- Lubben, Thomas H
- Stewart, Kent D
- Zinker, Bradley A
- Backes, Bradley J
- Judd, Andrew S
- Mulhern, Mathew
- Ballaron, Stephen J
- Stashko, Michael A
- Mika, Amanda K
- Beno, David W A
- Reinhart, Glenn A
- Fryer, Ryan M
- Preusser, Lee C
- Kempf-Grote, Anita J
- Sham, Hing L
- Trevillyan, James M
Producer: 20061205
In:
Journal of medicinal chemistry vol. 49
Availability: No items available.
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7.
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Discovery, structure-activity relationship, and pharmacological evaluation of (5-substituted-pyrrolidinyl-2-carbonyl)-2-cyanopyrrolidines as potent dipeptidyl peptidase IV inhibitors. [electronic resource] by
- Pei, Zhonghua
- Li, Xiaofeng
- Longenecker, Kenton
- von Geldern, Thomas W
- Wiedeman, Paul E
- Lubben, Thomas H
- Zinker, Bradley A
- Stewart, Kent
- Ballaron, Stephen J
- Stashko, Michael A
- Mika, Amanda K
- Beno, David W A
- Long, Michelle
- Wells, Heidi
- Kempf-Grote, Anita J
- Madar, David J
- McDermott, Todd S
- Bhagavatula, Lakshmi
- Fickes, Michael G
- Pireh, Daisy
- Solomon, Larry R
- Lake, Marc R
- Edalji, Rohinton
- Fry, Elizabeth H
- Sham, Hing L
- Trevillyan, James M
Producer: 20060731
In:
Journal of medicinal chemistry vol. 49
Availability: No items available.
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8.
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Discovery of 2-[4-{{2-(2S,5R)-2-cyano-5-ethynyl-1-pyrrolidinyl]-2-oxoethyl]amino]- 4-methyl-1-piperidinyl]-4-pyridinecarboxylic acid (ABT-279): a very potent, selective, effective, and well-tolerated inhibitor of dipeptidyl peptidase-IV, useful for the treatment of diabetes. [electronic resource] by
- Madar, David J
- Kopecka, Hana
- Pireh, Daisy
- Yong, Hong
- Pei, Zhonghua
- Li, Xiaofeng
- Wiedeman, Paul E
- Djuric, Stevan W
- Von Geldern, Thomas W
- Fickes, Michael G
- Bhagavatula, Lakshmi
- McDermott, Todd
- Wittenberger, Steven
- Richards, Steven J
- Longenecker, Kenton L
- Stewart, Kent D
- Lubben, Thomas H
- Ballaron, Stephen J
- Stashko, Michael A
- Long, Michelle A
- Wells, Heidi
- Zinker, Bradley A
- Mika, Amanda K
- Beno, David W A
- Kempf-Grote, Anita J
- Polakowski, James
- Segreti, Jason
- Reinhart, Glenn A
- Fryer, Ryan M
- Sham, Hing L
- Trevillyan, James M
Producer: 20061204
In:
Journal of medicinal chemistry vol. 49
Availability: No items available.
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