Results
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1.
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Crystal structures of ASK1-inhibtor complexes provide a platform for structure-based drug design. [electronic resource] by
- Singh, Onkar
- Shillings, Anthony
- Craggs, Peter
- Wall, Ian
- Rowland, Paul
- Skarzynski, Tadeusz
- Hobbs, Clare I
- Hardwick, Phil
- Tanner, Rob
- Blunt, Michelle
- Witty, David R
- Smith, Kathrine J
Producer: 20140207
In:
Protein science : a publication of the Protein Society vol. 22
Availability: No items available.
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2.
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Kinetic assay for characterization of spleen tyrosine kinase activity and inhibition with recombinant kinase and crude cell lysates. [electronic resource] by
- Li, Min
- Luraghi, Paolo
- Amour, Augustin
- Qian, Xiao-Dong
- Carter, Paul S
- Clark, C J
- Deakin, Angela
- Denyer, Jane
- Hobbs, Clare I
- Surby, Mark
- Patel, Vipul K
- Schaefer, Erik M
Producer: 20090123
In:
Analytical biochemistry vol. 384
Availability: No items available.
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3.
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Structural and mechanistic basis of differentiated inhibitors of the acute pancreatitis target kynurenine-3-monooxygenase. [electronic resource] by
- Hutchinson, Jonathan P
- Rowland, Paul
- Taylor, Mark R D
- Christodoulou, Erica M
- Haslam, Carl
- Hobbs, Clare I
- Holmes, Duncan S
- Homes, Paul
- Liddle, John
- Mole, Damian J
- Uings, Iain
- Walker, Ann L
- Webster, Scott P
- Mowat, Christopher G
- Chung, Chun-Wa
Producer: 20181121
In:
Nature communications vol. 8
Availability: No items available.
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4.
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1,3-Dimethyl Benzimidazolones Are Potent, Selective Inhibitors of the BRPF1 Bromodomain. [electronic resource] by
- Demont, Emmanuel H
- Bamborough, Paul
- Chung, Chun-Wa
- Craggs, Peter D
- Fallon, David
- Gordon, Laurie J
- Grandi, Paola
- Hobbs, Clare I
- Hussain, Jameed
- Jones, Emma J
- Le Gall, Armelle
- Michon, Anne-Marie
- Mitchell, Darren J
- Prinjha, Rab K
- Roberts, Andy D
- Sheppard, Robert J
- Watson, Robert J
Producer: 20141121
In:
ACS medicinal chemistry letters vol. 5
Availability: No items available.
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5.
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Discovery and Optimization of Potent, Selective, and in Vivo Efficacious 2-Aryl Benzimidazole BCATm Inhibitors. [electronic resource] by
- Deng, Hongfeng
- Zhou, Jingye
- Sundersingh, Flora
- Messer, Jeffrey A
- Somers, Donald O
- Ajakane, Myriam
- Arico-Muendel, Christopher C
- Beljean, Arthur
- Belyanskaya, Svetlana L
- Bingham, Ryan
- Blazensky, Emily
- Boullay, Anne-Benedicte
- Boursier, Eric
- Chai, Jing
- Carter, Paul
- Chung, Chun-Wa
- Daugan, Alain
- Ding, Yun
- Herry, Kenny
- Hobbs, Clare
- Humphries, Eric
- Kollmann, Christopher
- Nguyen, Van Loc
- Nicodeme, Edwige
- Smith, Sarah E
- Dodic, Nerina
- Ancellin, Nicolas
Producer: 20160420
In:
ACS medicinal chemistry letters vol. 7
Availability: No items available.
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6.
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GSK6853, a Chemical Probe for Inhibition of the BRPF1 Bromodomain. [electronic resource] by
- Bamborough, Paul
- Barnett, Heather A
- Becher, Isabelle
- Bird, Mark J
- Chung, Chun-Wa
- Craggs, Peter D
- Demont, Emmanuel H
- Diallo, Hawa
- Fallon, David J
- Gordon, Laurie J
- Grandi, Paola
- Hobbs, Clare I
- Hooper-Greenhill, Edward
- Jones, Emma J
- Law, Robert P
- Le Gall, Armelle
- Lugo, David
- Michon, Anne-Marie
- Mitchell, Darren J
- Prinjha, Rab K
- Sheppard, Robert J
- Watson, Allan J B
- Watson, Robert J
Producer: 20160621
In:
ACS medicinal chemistry letters vol. 7
Availability: No items available.
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7.
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Discovery of GSK143, a highly potent, selective and orally efficacious spleen tyrosine kinase inhibitor. [electronic resource] by
- Liddle, John
- Atkinson, Francis L
- Barker, Michael D
- Carter, Paul S
- Curtis, Neil R
- Davis, Rob P
- Douault, Clement
- Dickson, Marion C
- Elwes, Dorothy
- Garton, Neil S
- Gray, Matthew
- Hayhow, Thomas G
- Hobbs, Clare I
- Jones, Emma
- Leach, Stuart
- Leavens, Karen
- Lewis, Huw D
- McCleary, Scott
- Neu, Margarete
- Patel, Vipulkumar K
- Preston, Alex G S
- Ramirez-Molina, Cesar
- Shipley, Tracy J
- Skone, Philip A
- Smithers, Nick
- Somers, Donald O
- Walker, Ann L
- Watson, Robert J
- Weingarten, Gordon G
Producer: 20120118
In:
Bioorganic & medicinal chemistry letters vol. 21
Availability: No items available.
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8.
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The Discovery of in Vivo Active Mitochondrial Branched-Chain Aminotransferase (BCATm) Inhibitors by Hybridizing Fragment and HTS Hits. [electronic resource] by
- Bertrand, Sophie M
- Ancellin, Nicolas
- Beaufils, Benjamin
- Bingham, Ryan P
- Borthwick, Jennifer A
- Boullay, Anne-Bénédicte
- Boursier, Eric
- Carter, Paul S
- Chung, Chun-wa
- Churcher, Ian
- Dodic, Nerina
- Fouchet, Marie-Hélène
- Fournier, Charlène
- Francis, Peter L
- Gummer, Laura A
- Herry, Kenny
- Hobbs, Andrew
- Hobbs, Clare I
- Homes, Paul
- Jamieson, Craig
- Nicodeme, Edwige
- Pickett, Stephen D
- Reid, Iain H
- Simpson, Graham L
- Sloan, Lisa A
- Smith, Sarah E
- Somers, Donald O'N
- Spitzfaden, Claus
- Suckling, Colin J
- Valko, Klara
- Washio, Yoshiaki
- Young, Robert J
Producer: 20151229
In:
Journal of medicinal chemistry vol. 58
Availability: No items available.
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9.
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Discovery, SAR, and X-ray Binding Mode Study of BCATm Inhibitors from a Novel DNA-Encoded Library. [electronic resource] by
- Deng, Hongfeng
- Zhou, Jingye
- Sundersingh, Flora S
- Summerfield, Jennifer
- Somers, Don
- Messer, Jeffrey A
- Satz, Alexander L
- Ancellin, Nicolas
- Arico-Muendel, Christopher C
- Sargent Bedard, Katie L
- Beljean, Arthur
- Belyanskaya, Svetlana L
- Bingham, Ryan
- Smith, Sarah E
- Boursier, Eric
- Carter, Paul
- Centrella, Paolo A
- Clark, Matthew A
- Chung, Chun-Wa
- Davie, Christopher P
- Delorey, Jennifer L
- Ding, Yun
- Franklin, G Joseph
- Grady, LaShadric C
- Herry, Kenny
- Hobbs, Clare
- Kollmann, Christopher S
- Morgan, Barry A
- Pothier Kaushansky, Laura J
- Zhou, Quan
Producer: 20150820
In:
ACS medicinal chemistry letters vol. 6
Availability: No items available.
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