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Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. [electronic resource] by
- Mills, Evanna L
- Ryan, Dylan G
- Prag, Hiran A
- Dikovskaya, Dina
- Menon, Deepthi
- Zaslona, Zbigniew
- Jedrychowski, Mark P
- Costa, Ana S H
- Higgins, Maureen
- Hams, Emily
- Szpyt, John
- Runtsch, Marah C
- King, Martin S
- McGouran, Joanna F
- Fischer, Roman
- Kessler, Benedikt M
- McGettrick, Anne F
- Hughes, Mark M
- Carroll, Richard G
- Booty, Lee M
- Knatko, Elena V
- Meakin, Paul J
- Ashford, Michael L J
- Modis, Louise K
- Brunori, Gino
- Sévin, Daniel C
- Fallon, Padraic G
- Caldwell, Stuart T
- Kunji, Edmund R S
- Chouchani, Edward T
- Frezza, Christian
- Dinkova-Kostova, Albena T
- Hartley, Richard C
- Murphy, Michael P
- O'Neill, Luke A
Producer: 20180517
In:
Nature vol. 556
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942.
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DUB3 deubiquitinates and stabilizes NRF2 in chemotherapy resistance of colorectal cancer. [electronic resource] by
- Zhang, Qi
- Zhang, Ze-Yan
- Du, Huan
- Li, Shang-Ze
- Tu, Rongfu
- Jia, Yi-Fan
- Zheng, Zhe
- Song, Xue-Min
- Du, Run-Lei
- Zhang, Xiao-Dong
Producer: 20200908
In:
Cell death and differentiation vol. 26
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Distinct initiating events underpin the immune and metabolic heterogeneity of KRAS-mutant lung adenocarcinoma. [electronic resource] by
- Best, Sarah A
- Ding, Sheryl
- Kersbergen, Ariena
- Dong, Xueyi
- Song, Ji-Ying
- Xie, Yi
- Reljic, Boris
- Li, Kaiming
- Vince, James E
- Rathi, Vivek
- Wright, Gavin M
- Ritchie, Matthew E
- Sutherland, Kate D
Producer: 20191230
In:
Nature communications vol. 10
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Ursodeoxycholic acid stimulates Nrf2-mediated hepatocellular transport, detoxification, and antioxidative stress systems in mice. [electronic resource] by
- Okada, Kosuke
- Shoda, Junichi
- Taguchi, Keiko
- Maher, Jonathan M
- Ishizaki, Kaoru
- Inoue, Yoshimi
- Ohtsuki, Makio
- Goto, Nobuharu
- Takeda, Koichi
- Utsunomiya, Hirotoshi
- Oda, Koji
- Warabi, Eiji
- Ishii, Tetsuro
- Osaka, Keiko
- Hyodo, Ichinosuke
- Yamamoto, Masayuki
Producer: 20081126
In:
American journal of physiology. Gastrointestinal and liver physiology vol. 295
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949.
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Dysfunctional KEAP1-NRF2 interaction in non-small-cell lung cancer. [electronic resource] by
- Singh, Anju
- Misra, Vikas
- Thimmulappa, Rajesh K
- Lee, Hannah
- Ames, Stephen
- Hoque, Mohammad O
- Herman, James G
- Baylin, Stephen B
- Sidransky, David
- Gabrielson, Edward
- Brock, Malcolm V
- Biswal, Shyam
Producer: 20070109
In:
PLoS medicine vol. 3
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UHRF1 regulation of the Keap1-Nrf2 pathway in pancreatic cancer contributes to oncogenesis. [electronic resource] by
- Abu-Alainin, Wafa
- Gana, Thompson
- Liloglou, Triantafillos
- Olayanju, Adedamola
- Barrera, Lawrence N
- Ferguson, Robert
- Campbell, Fiona
- Andrews, Timothy
- Goldring, Christopher
- Kitteringham, Neil
- Park, Brian K
- Nedjadi, Taoufik
- Schmid, Michael C
- Slupsky, Joseph R
- Greenhalf, William
- Neoptolemos, John P
- Costello, Eithne
Producer: 20160524
In:
The Journal of pathology vol. 238
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Whole exome sequencing identifies driver mutations in asymptomatic computed tomography-detected lung cancers with normal karyotype. [electronic resource] by
- Belloni, Elena
- Veronesi, Giulia
- Rotta, Luca
- Volorio, Sara
- Sardella, Domenico
- Bernard, Loris
- Pece, Salvatore
- Di Fiore, Pier Paolo
- Fumagalli, Caterina
- Barberis, Massimo
- Spaggiari, Lorenzo
- Pelicci, Pier Giuseppe
- Riva, Laura
Producer: 20150806
In:
Cancer genetics vol. 208
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958.
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Nrf2 is commonly activated in papillary thyroid carcinoma, and it controls antioxidant transcriptional responses and viability of cancer cells. [electronic resource] by
- Ziros, Panos G
- Manolakou, Stavroula D
- Habeos, Ioannis G
- Lilis, Ioannis
- Chartoumpekis, Dionysios V
- Koika, Vasiliki
- Soares, Paula
- Kyriazopoulou, Venetsana E
- Scopa, Chrisoula D
- Papachristou, Dionysios J
- Sykiotis, Gerasimos P
Producer: 20131104
In:
The Journal of clinical endocrinology and metabolism vol. 98
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Modulations of Keap1-Nrf2 signaling axis by TIIA ameliorated the oxidative stress-induced myocardial apoptosis. [electronic resource] by
- Yan, Shi-Hai
- Zhao, Ning-Wei
- Geng, Zhi-Rong
- Shen, Jia-Yin
- Liu, Fu-Ming
- Yan, Dong
- Zhou, Jie
- Nie, Chao
- Huang, Cheng-Cai
- Fang, Zhu-Yuan
Producer: 20190503
In:
Free radical biology & medicine vol. 115
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