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81.
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ApoE promotes the proteolytic degradation of Abeta. [electronic resource] by
- Jiang, Qingguang
- Lee, C Y Daniel
- Mandrekar, Shweta
- Wilkinson, Brandy
- Cramer, Paige
- Zelcer, Noam
- Mann, Karen
- Lamb, Bruce
- Willson, Timothy M
- Collins, Jon L
- Richardson, Jill C
- Smith, Jonathan D
- Comery, Thomas A
- Riddell, David
- Holtzman, David M
- Tontonoz, Peter
- Landreth, Gary E
Producer: 20080710
In:
Neuron vol. 58
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82.
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Discovery of tertiary sulfonamides as potent liver X receptor antagonists. [electronic resource] by
- Zuercher, William J
- Buckholz, Richard G
- Campobasso, Nino
- Collins, Jon L
- Galardi, Cristin M
- Gampe, Robert T
- Hyatt, Stephen M
- Merrihew, Susan L
- Moore, John T
- Oplinger, Jeffrey A
- Reid, Paul R
- Spearing, Paul K
- Stanley, Thomas B
- Stewart, Eugene L
- Willson, Timothy M
Producer: 20100514
In:
Journal of medicinal chemistry vol. 53
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83.
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Optimized chemical probes for REV-ERBα. [electronic resource] by
- Trump, Ryan P
- Bresciani, Stefano
- Cooper, Anthony W J
- Tellam, James P
- Wojno, Justyna
- Blaikley, John
- Orband-Miller, Lisa A
- Kashatus, Jennifer A
- Boudjelal, Mohamed
- Dawson, Helen C
- Loudon, Andrew
- Ray, David
- Grant, Daniel
- Farrow, Stuart N
- Willson, Timothy M
- Tomkinson, Nicholas C O
Producer: 20130820
In:
Journal of medicinal chemistry vol. 56
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84.
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Discovery and Characterization of GSK2801, a Selective Chemical Probe for the Bromodomains BAZ2A and BAZ2B. [electronic resource] by
- Chen, Peiling
- Chaikuad, Apirat
- Bamborough, Paul
- Bantscheff, Marcus
- Bountra, Chas
- Chung, Chun-Wa
- Fedorov, Oleg
- Grandi, Paola
- Jung, David
- Lesniak, Robert
- Lindon, Matthew
- Müller, Susanne
- Philpott, Martin
- Prinjha, Rab
- Rogers, Catherine
- Selenski, Carolyn
- Tallant, Cynthia
- Werner, Thilo
- Willson, Timothy M
- Knapp, Stefan
- Drewry, David H
Producer: 20160726
In:
Journal of medicinal chemistry vol. 59
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85.
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Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARalpha. [electronic resource] by
- Xu, H Eric
- Stanley, Thomas B
- Montana, Valerie G
- Lambert, Millard H
- Shearer, Barry G
- Cobb, Jeffery E
- McKee, David D
- Galardi, Cristin M
- Plunket, Kelli D
- Nolte, Robert T
- Parks, Derek J
- Moore, John T
- Kliewer, Steven A
- Willson, Timothy M
- Stimmel, Julie B
Producer: 20020315
In:
Nature vol. 415
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86.
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Discovery of GSK1997132B a novel centrally penetrant benzimidazole PPARγ partial agonist. [electronic resource] by
- Sime, Mairi
- Allan, Amanda C
- Chapman, Paul
- Fieldhouse, Charlotte
- Giblin, Gerard M P
- Healy, Mark P
- Lambert, Millard H
- Leesnitzer, Lisa M
- Lewis, Ann
- Merrihew, Raymond V
- Rutter, Richard A
- Sasse, Rosemary
- Shearer, Barry G
- Willson, Timothy M
- Wilson, Timothy M
- Xu, Robert X
- Virley, David J
Producer: 20111219
In:
Bioorganic & medicinal chemistry letters vol. 21
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87.
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Functional consequences of cysteine modification in the ligand binding sites of peroxisome proliferator activated receptors by GW9662. [electronic resource] by
- Leesnitzer, Lisa M
- Parks, Derek J
- Bledsoe, Randy K
- Cobb, Jeff E
- Collins, Jon L
- Consler, Thomas G
- Davis, Roderick G
- Hull-Ryde, Emily A
- Lenhard, James M
- Patel, Lisa
- Plunket, Kelli D
- Shenk, Jennifer L
- Stimmel, Julie B
- Therapontos, Christina
- Willson, Timothy M
- Blanchard, Steven G
Producer: 20020626
In:
Biochemistry vol. 41
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88.
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Identification of a nonsteroidal liver X receptor agonist through parallel array synthesis of tertiary amines. [electronic resource] by
- Collins, Jon L
- Fivush, Adam M
- Watson, Michael A
- Galardi, Cristin M
- Lewis, Michael C
- Moore, Linda B
- Parks, Derek J
- Wilson, Joan G
- Tippin, Tim K
- Binz, Jane G
- Plunket, Kelli D
- Morgan, Daniel G
- Beaudet, Elizabeth J
- Whitney, Karl D
- Kliewer, Steven A
- Willson, Timothy M
Producer: 20020531
In:
Journal of medicinal chemistry vol. 45
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89.
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Synthetic LXR ligand inhibits the development of atherosclerosis in mice. [electronic resource] by
- Joseph, Sean B
- McKilligin, Elaine
- Pei, Liming
- Watson, Michael A
- Collins, Alan R
- Laffitte, Bryan A
- Chen, Mingyi
- Noh, Grace
- Goodman, Joanne
- Hagger, Graham N
- Tran, Jonathan
- Tippin, Tim K
- Wang, Xuping
- Lusis, Aldons J
- Hsueh, Willa A
- Law, Ronald E
- Collins, Jon L
- Willson, Timothy M
- Tontonoz, Peter
Producer: 20020701
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 99
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90.
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Peroxisome proliferator-activated receptor (PPAR)-beta/delta stimulates differentiation and lipid accumulation in keratinocytes. [electronic resource] by
- Schmuth, Matthias
- Haqq, Christopher M
- Cairns, William J
- Holder, Julie C
- Dorsam, Sheri
- Chang, Sandra
- Lau, Peggy
- Fowler, Ashley J
- Chuang, Gary
- Moser, Arthur H
- Brown, Barbara E
- Mao-Qiang, Man
- Uchida, Yoshikazu
- Schoonjans, Kristina
- Auwerx, Johan
- Chambon, P
- Willson, Timothy M
- Elias, Peter M
- Feingold, Kenneth R
Producer: 20040625
In:
The Journal of investigative dermatology vol. 122
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91.
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Tapinarof Is a Natural AhR Agonist that Resolves Skin Inflammation in Mice and Humans. [electronic resource] by
- Smith, Susan H
- Jayawickreme, Channa
- Rickard, David J
- Nicodeme, Edwige
- Bui, Thi
- Simmons, Cathy
- Coquery, Christine M
- Neil, Jessica
- Pryor, William M
- Mayhew, David
- Rajpal, Deepak K
- Creech, Katrina
- Furst, Sylvia
- Lee, James
- Wu, Dalei
- Rastinejad, Fraydoon
- Willson, Timothy M
- Viviani, Fabrice
- Morris, David C
- Moore, John T
- Cote-Sierra, Javier
Producer: 20171012
In:
The Journal of investigative dermatology vol. 137
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92.
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Application of Integrated Drug Screening/Kinome Analysis to Identify Inhibitors of Gemcitabine-Resistant Pancreatic Cancer Cell Growth. [electronic resource] by
- Krulikas, Linas J
- McDonald, Ian M
- Lee, Benjamin
- Okumu, Denis O
- East, Michael P
- Gilbert, Thomas S K
- Herring, Laura E
- Golitz, Brian T
- Wells, Carrow I
- Axtman, Allison D
- Zuercher, William J
- Willson, Timothy M
- Kireev, Dmitri
- Yeh, Jen Jen
- Johnson, Gary L
- Baines, Antonio T
- Graves, Lee M
Producer: 20190918
In:
SLAS discovery : advancing life sciences R & D vol. 23
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93.
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SGC-AAK1-1: A Chemical Probe Targeting AAK1 and BMP2K. [electronic resource] by
- Wells, Carrow
- Couñago, Rafael M
- Limas, Juanita C
- Almeida, Tuanny L
- Cook, Jeanette Gowen
- Drewry, David H
- Elkins, Jonathan M
- Gileadi, Opher
- Kapadia, Nirav R
- Lorente-Macias, Alvaro
- Pickett, Julie E
- Riemen, Alexander
- Ruela-de-Sousa, Roberta R
- Willson, Timothy M
- Zhang, Cunyu
- Zuercher, William J
- Zutshi, Reena
- Axtman, Alison D
Publication details: ACS medicinal chemistry letters Mar 2020
In:
ACS medicinal chemistry letters vol. 11
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94.
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Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1. [electronic resource] by
- Krylova, Irina N
- Sablin, Elena P
- Moore, Jamie
- Xu, Robert X
- Waitt, Gregory M
- MacKay, J Andrew
- Juzumiene, Dalia
- Bynum, Jane M
- Madauss, Kevin
- Montana, Valerie
- Lebedeva, Lioudmila
- Suzawa, Miyuki
- Williams, Jon D
- Williams, Shawn P
- Guy, Rodney K
- Thornton, Joseph W
- Fletterick, Robert J
- Willson, Timothy M
- Ingraham, Holly A
Producer: 20050329
In:
Cell vol. 120
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95.
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The phytoestrogen coumestrol is a naturally occurring antagonist of the human pregnane X receptor. [electronic resource] by
- Wang, Hongwei
- Li, Hao
- Moore, Linda B
- Johnson, Michael D L
- Maglich, Jodi M
- Goodwin, Bryan
- Ittoop, Olivia R R
- Wisely, Bruce
- Creech, Katrina
- Parks, Derek J
- Collins, Jon L
- Willson, Timothy M
- Kalpana, Ganjam V
- Venkatesh, Madhukumar
- Xie, Wen
- Cho, Sool Y
- Roboz, John
- Redinbo, Matthew
- Moore, John T
- Mani, Sridhar
Producer: 20080721
In:
Molecular endocrinology (Baltimore, Md.) vol. 22
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96.
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SGC-GAK-1: A Chemical Probe for Cyclin G Associated Kinase (GAK). [electronic resource] by
- Asquith, Christopher R M
- Berger, Benedict-Tilman
- Wan, Jing
- Bennett, James M
- Capuzzi, Stephen J
- Crona, Daniel J
- Drewry, David H
- East, Michael P
- Elkins, Jonathan M
- Fedorov, Oleg
- Godoi, Paulo H
- Hunter, Debra M
- Knapp, Stefan
- Müller, Susanne
- Torrice, Chad D
- Wells, Carrow I
- Earp, H Shelton
- Willson, Timothy M
- Zuercher, William J
Producer: 20200406
In:
Journal of medicinal chemistry vol. 62
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97.
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Structure-guided design of N-phenyl tertiary amines as transrepression-selective liver X receptor modulators with anti-inflammatory activity. [electronic resource] by
- Chao, Esther Y
- Caravella, Justin A
- Watson, Mike A
- Campobasso, Nino
- Ghisletti, Serena
- Billin, Andrew N
- Galardi, Cristin
- Wang, Ping
- Laffitte, Bryan A
- Iannone, Marie A
- Goodwin, Bryan J
- Nichols, Jason A
- Parks, Derek J
- Stewart, Eugene
- Wiethe, Robert W
- Williams, Shawn P
- Smallwood, Angela
- Pearce, Kenneth H
- Glass, Christopher K
- Willson, Timothy M
- Zuercher, William J
- Collins, Jon L
Producer: 20081009
In:
Journal of medicinal chemistry vol. 51
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98.
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Progress towards a public chemogenomic set for protein kinases and a call for contributions. [electronic resource] by
- Drewry, David H
- Wells, Carrow I
- Andrews, David M
- Angell, Richard
- Al-Ali, Hassan
- Axtman, Alison D
- Capuzzi, Stephen J
- Elkins, Jonathan M
- Ettmayer, Peter
- Frederiksen, Mathias
- Gileadi, Opher
- Gray, Nathanael
- Hooper, Alice
- Knapp, Stefan
- Laufer, Stefan
- Luecking, Ulrich
- Michaelides, Michael
- Müller, Susanne
- Muratov, Eugene
- Denny, R Aldrin
- Saikatendu, Kumar S
- Treiber, Daniel K
- Zuercher, William J
- Willson, Timothy M
Producer: 20171002
In:
PloS one vol. 12
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99.
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Circadian clock component REV-ERBα controls homeostatic regulation of pulmonary inflammation. [electronic resource] by
- Pariollaud, Marie
- Gibbs, Julie E
- Hopwood, Thomas W
- Brown, Sheila
- Begley, Nicola
- Vonslow, Ryan
- Poolman, Toryn
- Guo, Baoqiang
- Saer, Ben
- Jones, D Heulyn
- Tellam, James P
- Bresciani, Stefano
- Tomkinson, Nicholas Co
- Wojno-Picon, Justyna
- Cooper, Anthony Wj
- Daniels, Dion A
- Trump, Ryan P
- Grant, Daniel
- Zuercher, William
- Willson, Timothy M
- MacDonald, Andrew S
- Bolognese, Brian
- Podolin, Patricia L
- Sanchez, Yolanda
- Loudon, Andrew Si
- Ray, David W
Producer: 20190910
In:
The Journal of clinical investigation vol. 128
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100.
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Comprehensive characterization of the Published Kinase Inhibitor Set. [electronic resource] by
- Elkins, Jonathan M
- Fedele, Vita
- Szklarz, Marta
- Abdul Azeez, Kamal R
- Salah, Eidarus
- Mikolajczyk, Jowita
- Romanov, Sergei
- Sepetov, Nikolai
- Huang, Xi-Ping
- Roth, Bryan L
- Al Haj Zen, Ayman
- Fourches, Denis
- Muratov, Eugene
- Tropsha, Alex
- Morris, Joel
- Teicher, Beverly A
- Kunkel, Mark
- Polley, Eric
- Lackey, Karen E
- Atkinson, Francis L
- Overington, John P
- Bamborough, Paul
- Müller, Susanne
- Price, Daniel J
- Willson, Timothy M
- Drewry, David H
- Knapp, Stefan
- Zuercher, William J
Producer: 20160511
In:
Nature biotechnology vol. 34
Availability: No items available.
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