Results
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81.
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Characterization of Lead Compounds Targeting the Selenoprotein Thioredoxin Glutathione Reductase for Treatment of Schistosomiasis. [electronic resource] by
- Lyu, Haining
- Petukhov, Pavel A
- Banta, Paul R
- Jadhav, Ajit
- Lea, Wendy A
- Cheng, Qing
- Arnér, Elias S J
- Simeonov, Anton
- Thatcher, Gregory R J
- Angelucci, Francesco
- Williams, David L
Producer: 20210127
In:
ACS infectious diseases vol. 6
Availability: No items available.
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82.
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Mixed lineage kinase 3 inhibition induces T cell activation and cytotoxicity. [electronic resource] by
- Kumar, Sandeep
- Singh, Sunil Kumar
- Viswakarma, Navin
- Sondarva, Gautam
- Nair, Rakesh Sathish
- Sethupathi, Periannan
- Sinha, Subhash C
- Emmadi, Rajyasree
- Hoskins, Kent
- Danciu, Oana
- Thatcher, Gregory R J
- Rana, Basabi
- Rana, Ajay
Producer: 20200720
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 117
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83.
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Molecular modeling, synthesis, and activity studies of novel biaryl and fused-ring BACE1 inhibitors. [electronic resource] by
- Chirapu, Srinivas Reddy
- Pachaiyappan, Boobalan
- Nural, Hikmet F
- Cheng, Xin
- Yuan, Hongbin
- Lankin, David C
- Abdul-Hay, Samer O
- Thatcher, Gregory R J
- Shen, Yong
- Kozikowski, Alan P
- Petukhov, Pavel A
Producer: 20090128
In:
Bioorganic & medicinal chemistry letters vol. 19
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84.
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Novel selective estrogen mimics for the treatment of tamoxifen-resistant breast cancer. [electronic resource] by
- Molloy, Mary Ellen
- White, Bethany E Perez
- Gherezghiher, Teshome
- Michalsen, Bradley T
- Xiong, Rui
- Patel, Hitisha
- Zhao, Huiping
- Maximov, Philipp Y
- Jordan, V Craig
- Thatcher, Gregory R J
- Tonetti, Debra A
Producer: 20151110
In:
Molecular cancer therapeutics vol. 13
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85.
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Re-engineering a neuroprotective, clinical drug as a procognitive agent with high in vivo potency and with GABAA potentiating activity for use in dementia. [electronic resource] by
- Luo, Jia
- Lee, Sue H
- VandeVrede, Lawren
- Qin, Zhihui
- Piyankarage, Sujeewa
- Tavassoli, Ehsan
- Asghodom, Rezene T
- Ben Aissa, Manel
- Fà, Mauro
- Arancio, Ottavio
- Yue, Lan
- Pepperberg, David R
- Thatcher, Gregory R J
Producer: 20160706
In:
BMC neuroscience vol. 16
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86.
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Hops (Humulus lupulus) inhibits oxidative estrogen metabolism and estrogen-induced malignant transformation in human mammary epithelial cells (MCF-10A). [electronic resource] by
- Hemachandra, L P
- Madhubhani, P
- Chandrasena, R
- Esala, P
- Chen, Shao-Nong
- Main, Matthew
- Lankin, David C
- Scism, Robert A
- Dietz, Birgit M
- Pauli, Guido F
- Thatcher, Gregory R J
- Bolton, Judy L
Producer: 20120508
In:
Cancer prevention research (Philadelphia, Pa.) vol. 5
Availability: No items available.
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87.
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Design, synthesis, and optimization of novel epoxide incorporating peptidomimetics as selective calpain inhibitors. [electronic resource] by
- Schiefer, Isaac T
- Tapadar, Subhasish
- Litosh, Vladislav
- Siklos, Marton
- Scism, Rob
- Wijewickrama, Gihani T
- Chandrasena, Esala P
- Sinha, Vaishali
- Tavassoli, Ehsan
- Brunsteiner, Michael
- Fa', Mauro
- Arancio, Ottavio
- Petukhov, Pavel
- Thatcher, Gregory R J
Producer: 20131111
In:
Journal of medicinal chemistry vol. 56
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88.
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Ectopic suicide inhibition of thioredoxin glutathione reductase. [electronic resource] by
- Silvestri, Ilaria
- Lyu, Haining
- Fata, Francesca
- Banta, Paul R
- Mattei, Benedetta
- Ippoliti, Rodolfo
- Bellelli, Andrea
- Pitari, Giuseppina
- Ardini, Matteo
- Petukhova, Valentina
- Thatcher, Gregory R J
- Petukhov, Pavel A
- Williams, David L
- Angelucci, Francesco
Producer: 20210618
In:
Free radical biology & medicine vol. 147
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89.
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Novel Selective Calpain 1 Inhibitors as Potential Therapeutics in Alzheimer's Disease. [electronic resource] by
- Fà, Mauro
- Zhang, Hong
- Staniszewski, Agnieszka
- Saeed, Faisal
- Shen, Li W
- Schiefer, Isaac T
- Siklos, Marton I
- Tapadar, Subhasish
- Litosh, Vladislav A
- Libien, Jenny
- Petukhov, Pavel A
- Teich, Andrew F
- Thatcher, Gregory R J
- Arancio, Ottavio
Producer: 20161101
In:
Journal of Alzheimer's disease : JAD vol. 49
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90.
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Selective Human Estrogen Receptor Partial Agonists (ShERPAs) for Tamoxifen-Resistant Breast Cancer. [electronic resource] by
- Xiong, Rui
- Patel, Hitisha K
- Gutgesell, Lauren M
- Zhao, Jiong
- Delgado-Rivera, Loruhama
- Pham, Thao N D
- Zhao, Huiping
- Carlson, Kathryn
- Martin, Teresa
- Katzenellenbogen, John A
- Moore, Terry W
- Tonetti, Debra A
- Thatcher, Gregory R J
Producer: 20160518
In:
Journal of medicinal chemistry vol. 59
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91.
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A multifunctional therapeutic approach to disease modification in multiple familial mouse models and a novel sporadic model of Alzheimer's disease. [electronic resource] by
- Luo, Jia
- Lee, Sue H
- VandeVrede, Lawren
- Qin, Zhihui
- Ben Aissa, Manel
- Larson, John
- Teich, Andrew F
- Arancio, Ottavio
- D'Souza, Yohan
- Elharram, Ahmed
- Koster, Kevin
- Tai, Leon M
- LaDu, Mary Jo
- Bennett, Brian M
- Thatcher, Gregory R J
Producer: 20161108
In:
Molecular neurodegeneration vol. 11
Availability: No items available.
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92.
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Erratum to: A multifunctional therapeutic approach to disease modification in multiple familial mouse models and a novel sporadic model of Alzheimer's disease. [electronic resource] by
- Luo, Jia
- Lee, Sue H
- VandeVrede, Lawren
- Qin, Zhihui
- Aissa, Manel Ben
- Larson, John
- Teich, Andrew F
- Arancio, Ottavio
- D'Souza, Yohan
- Elharram, Ahmed
- Koster, Kevin
- Tai, Leon M
- LaDu, Mary Jo
- Bennett, Brian M
- Thatcher, Gregory R J
Publication details: Molecular neurodegeneration May 2016
In:
Molecular neurodegeneration vol. 11
Availability: No items available.
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93.
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SERMs attenuate estrogen-induced malignant transformation of human mammary epithelial cells by upregulating detoxification of oxidative metabolites. [electronic resource] by
- Hemachandra, L P Madhubhani P
- Patel, Hitisha
- Chandrasena, R Esala P
- Choi, Jaewoo
- Piyankarage, Sujeewa C
- Wang, Shuai
- Wang, Yijin
- Thayer, Emily N
- Scism, Robert A
- Michalsen, Bradley T
- Xiong, Rui
- Siklos, Marton I
- Bolton, Judy L
- Thatcher, Gregory R J
Producer: 20150109
In:
Cancer prevention research (Philadelphia, Pa.) vol. 7
Availability: No items available.
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94.
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Activation of Nrf2 and Hypoxic Adaptive Response Contribute to Neuroprotection Elicited by Phenylhydroxamic Acid Selective HDAC6 Inhibitors. [electronic resource] by
- Gaisina, Irina N
- Lee, Sue H
- Kaidery, Navneet A
- Ben Aissa, Manel
- Ahuja, Manuj
- Smirnova, Natalya N
- Wakade, Sushama
- Gaisin, Arsen
- Bourassa, Megan W
- Ratan, Rajiv R
- Nikulin, Sergey V
- Poloznikov, Andrey A
- Thomas, Bobby
- Thatcher, Gregory R J
- Gazaryan, Irina G
Producer: 20190521
In:
ACS chemical neuroscience vol. 9
Availability: No items available.
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95.
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Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as "Doorstop" for NADPH Entry. [electronic resource] by
- Silvestri, Ilaria
- Lyu, Haining
- Fata, Francesca
- Boumis, Giovanna
- Miele, Adriana E
- Ardini, Matteo
- Ippoliti, Rodolfo
- Bellelli, Andrea
- Jadhav, Ajit
- Lea, Wendy A
- Simeonov, Anton
- Cheng, Qing
- Arnér, Elias S J
- Thatcher, Gregory R J
- Petukhov, Pavel A
- Williams, David L
- Angelucci, Francesco
Producer: 20190313
In:
ACS chemical biology vol. 13
Availability: No items available.
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96.
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Design and Synthesis of Basic Selective Estrogen Receptor Degraders for Endocrine Therapy Resistant Breast Cancer. [electronic resource] by
- Lu, Yunlong
- Gutgesell, Lauren M
- Xiong, Rui
- Zhao, Jiong
- Li, Yangfeng
- Rosales, Carlo I
- Hollas, Michael
- Shen, Zhengnan
- Gordon-Blake, Jesse
- Dye, Katherine
- Wang, Yueting
- Lee, Sue
- Chen, Hu
- He, Donghong
- Dubrovyskyii, Oleksii
- Zhao, Huiping
- Huang, Fei
- Lasek, Amy W
- Tonetti, Debra A
- Thatcher, Gregory R J
Producer: 20200622
In:
Journal of medicinal chemistry vol. 62
Availability: No items available.
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97.
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G1T48, an oral selective estrogen receptor degrader, and the CDK4/6 inhibitor lerociclib inhibit tumor growth in animal models of endocrine-resistant breast cancer. [electronic resource] by
- Andreano, Kaitlyn J
- Wardell, Suzanne E
- Baker, Jennifer G
- Desautels, Taylor K
- Baldi, Robert
- Chao, Christina A
- Heetderks, Kendall A
- Bae, Yeeun
- Xiong, Rui
- Tonetti, Debra A
- Gutgesell, Lauren M
- Zhao, Jiong
- Sorrentino, Jessica A
- Thompson, Delita A
- Bisi, John E
- Strum, Jay C
- Thatcher, Gregory R J
- Norris, John D
Producer: 20201210
In:
Breast cancer research and treatment vol. 180
Availability: No items available.
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