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	81.	Allele-specific suppression of mutant huntingtin using antisense oligonucleotides: providing a therapeutic option for all Huntington disease patients. [electronic resource] by Skotte, Niels H Southwell, Amber L Østergaard, Michael E Carroll, Jeffrey B Warby, Simon C Doty, Crystal N Petoukhov, Eugenia Vaid, Kuljeet Kordasiewicz, Holly Watt, Andrew T Freier, Susan M Hung, Gene Seth, Punit P Bennett, C Frank Swayze, Eric E Hayden, Michael R Producer: 20160331 In: PloS one vol. 9 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	82.	Site-specific replacement of phosphorothioate with alkyl phosphonate linkages enhances the therapeutic profile of gapmer ASOs by modulating interactions with cellular proteins. [electronic resource] by Migawa, Michael T Shen, Wen Wan, W Brad Vasquez, Guillermo Oestergaard, Michael E Low, Audrey De Hoyos, Cheryl L Gupta, Ruchi Murray, Susan Tanowitz, Michael Bell, Melanie Nichols, Joshua G Gaus, Hans Liang, Xue-Hai Swayze, Eric E Crooke, Stanley T Seth, Punit P Producer: 20191125 In: Nucleic acids research vol. 47 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	83.	DNA/RNA heteroduplex oligonucleotide for highly efficient gene silencing. [electronic resource] by Nishina, Kazutaka Piao, Wenying Yoshida-Tanaka, Kie Sujino, Yumiko Nishina, Tomoko Yamamoto, Tsuyoshi Nitta, Keiko Yoshioka, Kotaro Kuwahara, Hiroya Yasuhara, Hidenori Baba, Takeshi Ono, Fumiko Miyata, Kanjiro Miyake, Koichi Seth, Punit P Low, Audrey Yoshida, Masayuki Bennett, C Frank Kataoka, Kazunori Mizusawa, Hidehiro Obika, Satoshi Yokota, Takanori Producer: 20160427 In: Nature communications vol. 6 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	84.	Chemical modification of PS-ASO therapeutics reduces cellular protein-binding and improves the therapeutic index. [electronic resource] by Shen, Wen De Hoyos, Cheryl L Migawa, Michael T Vickers, Timothy A Sun, Hong Low, Audrey Bell, Thomas A Rahdar, Meghdad Mukhopadhyay, Swagatam Hart, Christopher E Bell, Melanie Riney, Stan Murray, Susan F Greenlee, Sarah Crooke, Rosanne M Liang, Xue-Hai Seth, Punit P Crooke, Stanley T Producer: 20190703 In: Nature biotechnology vol. 37 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	85.	Hepatotoxicity of high affinity gapmer antisense oligonucleotides is mediated by RNase H1 dependent promiscuous reduction of very long pre-mRNA transcripts. [electronic resource] by Burel, Sebastien A Hart, Christopher E Cauntay, Patrick Hsiao, Jill Machemer, Todd Katz, Melanie Watt, Andy Bui, Huynh-Hoa Younis, Husam Sabripour, Mahyar Freier, Susan M Hung, Gene Dan, Amy Prakash, T P Seth, Punit P Swayze, Eric E Bennett, C Frank Crooke, Stanley T Henry, Scott P Producer: 20160808 In: Nucleic acids research vol. 44 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	86.	Targeted delivery of antisense oligonucleotides to hepatocytes using triantennary N-acetyl galactosamine improves potency 10-fold in mice. [electronic resource] by Prakash, Thazha P Graham, Mark J Yu, Jinghua Carty, Rick Low, Audrey Chappell, Alfred Schmidt, Karsten Zhao, Chenguang Aghajan, Mariam Murray, Heather F Riney, Stan Booten, Sheri L Murray, Susan F Gaus, Hans Crosby, Jeff Lima, Walt F Guo, Shuling Monia, Brett P Swayze, Eric E Seth, Punit P Producer: 20141014 In: Nucleic acids research vol. 42 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	87.	Huntingtin suppression restores cognitive function in a mouse model of Huntington's disease. [electronic resource] by Southwell, Amber L Kordasiewicz, Holly B Langbehn, Douglas Skotte, Niels H Parsons, Matthew P Villanueva, Erika B Caron, Nicholas S Østergaard, Michael E Anderson, Lisa M Xie, Yuanyun Cengio, Louisa Dal Findlay-Black, Hailey Doty, Crystal N Fitsimmons, Bethany Swayze, Eric E Seth, Punit P Raymond, Lynn A Frank Bennett, C Hayden, Michael R Producer: 20191011 In: Science translational medicine vol. 10 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	88.	A novel humanized mouse model of Huntington disease for preclinical development of therapeutics targeting mutant huntingtin alleles. [electronic resource] by Southwell, Amber L Skotte, Niels H Villanueva, Erika B Østergaard, Michael E Gu, Xiaofeng Kordasiewicz, Holly B Kay, Chris Cheung, Daphne Xie, Yuanyun Waltl, Sabine Dal Cengio, Louisa Findlay-Black, Hailey Doty, Crystal N Petoukhov, Eugenia Iworima, Diepiriye Slama, Ramy Ooi, Jolene Pouladi, Mahmoud A Yang, X William Swayze, Eric E Seth, Punit P Hayden, Michael R Producer: 20170515 In: Human molecular genetics vol. 26 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	89.	Conjugation of hydrophobic moieties enhances potency of antisense oligonucleotides in the muscle of rodents and non-human primates. [electronic resource] by Østergaard, Michael E Jackson, Michaela Low, Audrey E Chappell, Alfred G Lee, Richard Peralta, Rachel Q Yu, Jinghua Kinberger, Garth A Dan, Amy Carty, Rick Tanowitz, Michael Anderson, Patrick Kim, Tae-Won Fradkin, Linda Mullick, Adam E Murray, Sue Rigo, Frank Prakash, Thazha P Bennett, C Frank Swayze, Eric E Gaus, Hans J Seth, Punit P Producer: 20200225 In: Nucleic acids research vol. 47 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	90.	Comprehensive Structure-Activity Relationship of Triantennary N-Acetylgalactosamine Conjugated Antisense Oligonucleotides for Targeted Delivery to Hepatocytes. [electronic resource] by Prakash, Thazha P Yu, Jinghua Migawa, Michael T Kinberger, Garth A Wan, W Brad Østergaard, Michael E Carty, Recaldo L Vasquez, Guillermo Low, Audrey Chappell, Alfred Schmidt, Karsten Aghajan, Mariam Crosby, Jeff Murray, Heather M Booten, Sheri L Hsiao, Jill Soriano, Armand Machemer, Todd Cauntay, Patrick Burel, Sebastien A Murray, Susan F Gaus, Hans Graham, Mark J Swayze, Eric E Seth, Punit P Producer: 20160823 In: Journal of medicinal chemistry vol. 59 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)

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