Results
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81.
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Highly potent, orally active diester macrocyclic human renin inhibitors. [electronic resource] by
- Weber, A E
- Steiner, M G
- Krieter, P A
- Colletti, A E
- Tata, J R
- Halgren, T A
- Ball, R G
- Doyle, J J
- Schorn, T W
- Stearns, R A
Producer: 19921127
In:
Journal of medicinal chemistry vol. 35
Availability: No items available.
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82.
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Bioactivation of diclofenac via benzoquinone imine intermediates-identification of urinary mercapturic acid derivatives in rats and humans. [electronic resource] by
- Poon, G K
- Chen, Q
- Teffera, Y
- Ngui, J S
- Griffin, P R
- Braun, M P
- Doss, G A
- Freeden, C
- Stearns, R A
- Evans, D C
- Baillie, T A
- Tang, W
Producer: 20020131
In:
Drug metabolism and disposition: the biological fate of chemicals vol. 29
Availability: No items available.
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83.
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In vitro and in vivo metabolism of a novel cannabinoid-1 receptor inverse agonist, taranabant, in rats and monkeys. [electronic resource] by
- Reddy, V B G
- Doss, G A
- Karanam, B V
- Samuel, K
- Lanza, T J
- Lin, L S
- Yu, N X
- Zhang, A S
- Raab, C E
- Stearns, R A
- Kumar, S
Producer: 20110602
In:
Xenobiotica; the fate of foreign compounds in biological systems vol. 40
Availability: No items available.
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84.
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Interaction of diclofenac and quinidine in monkeys: stimulation of diclofenac metabolism. [electronic resource] by
- Tang, W
- Stearns, R A
- Kwei, G Y
- Iliff, S A
- Miller, R R
- Egan, M A
- Yu, N X
- Dean, D C
- Kumar, S
- Shou, M
- Lin, J H
- Baillie, T A
Producer: 19991220
In:
The Journal of pharmacology and experimental therapeutics vol. 291
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85.
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Importance of mechanistic drug metabolism studies in support of drug discovery: A case study with an N -sulfonylated dipeptide VLA-4 antagonist in rats. [electronic resource] by
- Tang, W
- Stearns, R A
- Chen, Q
- Bleasby, K
- Teffera, Y
- Colletti, A
- Hafey, M
- Evers, R
- Dean, D C
- Magriotis, P A
- Lanza, T J
- Lin, L S
- Hagmann, W K
- Baillie, T A
Producer: 20080509
In:
Xenobiotica; the fate of foreign compounds in biological systems vol. 38
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86.
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Studies on cytochrome P-450-mediated bioactivation of diclofenac in rats and in human hepatocytes: identification of glutathione conjugated metabolites. [electronic resource] by
- Tang, W
- Stearns, R A
- Bandiera, S M
- Zhang, Y
- Raab, C
- Braun, M P
- Dean, D C
- Pang, J
- Leung, K H
- Doss, G A
- Strauss, J R
- Kwei, G Y
- Rushmore, T H
- Chiu, S H
- Baillie, T A
Producer: 19990407
In:
Drug metabolism and disposition: the biological fate of chemicals vol. 27
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87.
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Discovery of a potent, orally bioavailable beta(3) adrenergic receptor agonist, (R)-N-[4-[2-[[2-hydroxy-2-(3-pyridinyl)ethyl]amino]ethyl]phenyl]-4-[4 -[4-(trifluoromethyl)phenyl]thiazol-2-yl]benzenesulfonamide. [electronic resource] by
- Mathvink, R J
- Tolman, J S
- Chitty, D
- Candelore, M R
- Cascieri, M A
- Colwell, L F
- Deng, L
- Feeney, W P
- Forrest, M J
- Hom, G J
- MacIntyre, D E
- Miller, R R
- Stearns, R A
- Tota, L
- Wyvratt, M J
- Fisher, M H
- Weber, A E
Producer: 20001116
In:
Journal of medicinal chemistry vol. 43
Availability: No items available.
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88.
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L-770,644: a potent and selective human beta3 adrenergic receptor agonist with improved oral bioavailability. [electronic resource] by
- Shih, T L
- Candelore, M R
- Cascieri, M A
- Chiu, S H
- Colwell, L F
- Deng, L
- Feeney, W P
- Forrest, M J
- Hom, G J
- MacIntyre, D E
- Miller, R R
- Stearns, R A
- Strader, C D
- Tota, L
- Wyvratt, M J
- Fisher, M H
- Weber, A E
Producer: 19990819
In:
Bioorganic & medicinal chemistry letters vol. 9
Availability: No items available.
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89.
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Discovery of an orally bioavailable alkyl oxadiazole beta3 adrenergic receptor agonist. [electronic resource] by
- Feng, D D
- Biftu, T
- Candelore, M R
- Cascieri, M A
- Colwell, L F
- Deng, L
- Feeney, W P
- Forrest, M J
- Hom, G J
- MacIntyre, D E
- Miller, R R
- Stearns, R A
- Strader, C D
- Tota, L
- Wyvratt, M J
- Fisher, M H
- Weber, A E
Producer: 20001107
In:
Bioorganic & medicinal chemistry letters vol. 10
Availability: No items available.
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90.
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Synthesis and SAR of benzyl and phenoxymethylene oxadiazole benzenesulfonamides as selective beta3 adrenergic receptor agonist antiobesity agents. [electronic resource] by
- Biftu, T
- Feng, D D
- Liang, G B
- Kuo, H
- Qian, X
- Naylor, E M
- Colandrea, V J
- Candelore, M R
- Cascieri, M A
- Colwell, L F
- Forrest, M J
- Hom, G J
- MacIntyre, D E
- Stearns, R A
- Strader, C D
- Wyvratt, M J
- Fisher, M H
- Weber, A E
Producer: 20001107
In:
Bioorganic & medicinal chemistry letters vol. 10
Availability: No items available.
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91.
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Human beta3 adrenergic receptor agonists containing cyclic ureidobenzenesulfonamides. [electronic resource] by
- Parmee, E R
- Naylor, E M
- Perkins, L
- Colandrea, V J
- Ok, H O
- Candelore, M R
- Cascieri, M A
- Deng, L
- Feeney, W P
- Forrest, M J
- Hom, G J
- MacIntyre, D E
- Miller, R R
- Stearns, R A
- Strader, C D
- Tota, L
- Wyvratt, M J
- Fisher, M H
- Weber, A E
Producer: 19990604
In:
Bioorganic & medicinal chemistry letters vol. 9
Availability: No items available.
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92.
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3-Pyridyloxypropanolamine agonists of the beta 3 adrenergic receptor with improved pharmacokinetic properties. [electronic resource] by
- Weber, A E
- Ok, H O
- Alvaro, R F
- Candelore, M R
- Cascieri, M A
- Chiu, S H
- Deng, L
- Forrest, M J
- Hom, G J
- Hutchins, J E
- Kao, J
- MacIntyre, D E
- Mathvink, R J
- McLoughlin, D
- Miller, R R
- Newbold, R C
- Olah, T V
- Parmee, E R
- Perkins, L
- Stearns, R A
- Strader, C D
- Szumiloski, J
- Tang, Y S
- Tota, L
- Fisher, M H
Producer: 19990128
In:
Bioorganic & medicinal chemistry letters vol. 8
Availability: No items available.
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93.
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A selective human beta3 adrenergic receptor agonist increases metabolic rate in rhesus monkeys. [electronic resource] by
- Fisher, M H
- Amend, A M
- Bach, T J
- Barker, J M
- Brady, E J
- Candelore, M R
- Carroll, D
- Cascieri, M A
- Chiu, S H
- Deng, L
- Forrest, M J
- Hegarty-Friscino, B
- Guan, X M
- Hom, G J
- Hutchins, J E
- Kelly, L J
- Mathvink, R J
- Metzger, J M
- Miller, R R
- Ok, H O
- Parmee, E R
- Saperstein, R
- Strader, C D
- Stearns, R A
- MacIntyre, D E
Producer: 19980626
In:
The Journal of clinical investigation vol. 101
Availability: No items available.
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94.
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The discovery of sulfonylated dipeptides as potent VLA-4 antagonists. [electronic resource] by
- Hagmann, W K
- Durette, P L
- Lanza, T
- Kevin, N J
- de Laszlo, S E
- Kopka, I E
- Young, D
- Magriotis, P A
- Li, B
- Lin, L S
- Yang, G
- Kamenecka, T
- Chang, L L
- Wilson, J
- MacCoss, M
- Mills, S G
- Van Riper, G
- McCauley, E
- Egger, L A
- Kidambi, U
- Lyons, K
- Vincent, S
- Stearns, R
- Colletti, A
- Teffera, J
- Tong, S
- Fenyk-Melody, J
- Owens, K
- Levorse, D
- Kim, P
- Schmidt, J A
- Mumford, R A
Producer: 20011210
In:
Bioorganic & medicinal chemistry letters vol. 11
Availability: No items available.
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