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Afatinib alone or afatinib plus vinorelbine versus investigator's choice of treatment for HER2-positive breast cancer with progressive brain metastases after trastuzumab, lapatinib, or both (LUX-Breast 3): a randomised, open-label, multicentre, phase 2 trial. [electronic resource] by
- Cortés, Javier
- Dieras, Véronique
- Ro, Jungsil
- Barriere, Jérôme
- Bachelot, Thomas
- Hurvitz, Sara
- Le Rhun, Emilie
- Espié, Marc
- Kim, Sung-Bae
- Schneeweiss, Andreas
- Sohn, Joo Hyuk
- Nabholtz, Jean-Marc
- Kellokumpu-Lehtinen, Pirkko-Liisa
- Taguchi, Julie
- Piacentini, Federico
- Ciruelos, Eva
- Bono, Petri
- Ould-Kaci, Mahmoud
- Roux, Flavien
- Joensuu, Heikki
Producer: 20160418
In:
The Lancet. Oncology vol. 16
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682.
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683.
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684.
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685.
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686.
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687.
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Effects of pharmacokinetics-related genetic polymorphisms on the side effect profile of afatinib in patients with non-small cell lung cancer. [electronic resource] by
- Hayashi, Hideki
- Iihara, Hirotoshi
- Hirose, Chiemi
- Fukuda, Yoshihisa
- Kitahora, Mika
- Kaito, Daizo
- Yanase, Komei
- Endo, Junki
- Ohno, Yasushi
- Suzuki, Akio
- Sugiyama, Tadashi
Producer: 20200622
In:
Lung cancer (Amsterdam, Netherlands) vol. 134
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688.
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Genetic and chemical targeting of epithelial-restricted with serine box reduces EGF receptor and potentiates the efficacy of afatinib. [electronic resource] by
- Zhang, Manchao
- Taylor, Christopher E
- Piao, Longzhu
- Datta, Jharna
- Bruno, Paul A
- Bhave, Sanjay
- Su, Tizhi
- Lang, James C
- Xie, Xiujie
- Teknos, Theodoros N
- Mapp, Anna K
- Pan, Quintin
Producer: 20140401
In:
Molecular cancer therapeutics vol. 12
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689.
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690.
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The dual PI3K/mTOR inhibitor BEZ235 restricts the growth of lung cancer tumors regardless of EGFR status, as a potent accompanist in combined therapeutic regimens. [electronic resource] by
- Wu, Yi-Ying
- Wu, Hung-Chang
- Wu, Jia-En
- Huang, Kuo-Yen
- Yang, Shuenn-Chen
- Chen, Si-Xuan
- Tsao, Chao-Jung
- Hsu, Keng-Fu
- Chen, Yuh-Ling
- Hong, Tse-Ming
Producer: 20191211
In:
Journal of experimental & clinical cancer research : CR vol. 38
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691.
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Afatinib against Esophageal or Head-and-Neck Squamous Cell Carcinoma: Significance of Activating Oncogenic HER4 Mutations in HNSCC. [electronic resource] by
- Nakamura, Yu
- Togashi, Yosuke
- Nakahara, Hirokazu
- Tomida, Shuta
- Banno, Eri
- Terashima, Masato
- Hayashi, Hidetoshi
- de Velasco, Marco A
- Sakai, Kazuko
- Fujita, Yoshihiko
- Okegawa, Takatsugu
- Nutahara, Kikuo
- Hamada, Suguru
- Nishio, Kazuto
Producer: 20170629
In:
Molecular cancer therapeutics vol. 15
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692.
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EPHA2 blockade reverses acquired resistance to afatinib induced by EPHA2-mediated MAPK pathway activation in gastric cancer cells and avatar mice. [electronic resource] by
- Chen, Zuhua
- Liu, Zhentao
- Zhang, Mengqi
- Huang, Wenwen
- Li, Zhongwu
- Wang, Shubin
- Zhang, Cheng
- Dong, Bin
- Gao, Jing
- Shen, Lin
Producer: 20200124
In:
International journal of cancer vol. 145
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693.
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Dual targeting of EGFR can overcome a major drug resistance mutation in mouse models of EGFR mutant lung cancer. [electronic resource] by
- Regales, Lucia
- Gong, Yixuan
- Shen, Ronglai
- de Stanchina, Elisa
- Vivanco, Igor
- Goel, Aviva
- Koutcher, Jason A
- Spassova, Maria
- Ouerfelli, Ouathek
- Mellinghoff, Ingo K
- Zakowski, Maureen F
- Politi, Katerina A
- Pao, William
Producer: 20100209
In:
The Journal of clinical investigation vol. 119
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694.
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Stress hormones promote EGFR inhibitor resistance in NSCLC: Implications for combinations with β-blockers. [electronic resource] by
- Nilsson, Monique B
- Sun, Huiying
- Diao, Lixia
- Tong, Pan
- Liu, Diane
- Li, Lerong
- Fan, Youhong
- Poteete, Alissa
- Lim, Seung-Oe
- Howells, Kathryn
- Haddad, Vincent
- Gomez, Daniel
- Tran, Hai
- Pena, Guillermo Armaiz
- Sequist, Lecia V
- Yang, James C
- Wang, Jing
- Kim, Edward S
- Herbst, Roy
- Lee, J Jack
- Hong, Waun Ki
- Wistuba, Ignacio
- Hung, Mien-Chie
- Sood, Anil K
- Heymach, John V
Producer: 20180622
In:
Science translational medicine vol. 9
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697.
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698.
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699.
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RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer. [electronic resource] by
- Niederst, Matthew J
- Sequist, Lecia V
- Poirier, John T
- Mermel, Craig H
- Lockerman, Elizabeth L
- Garcia, Angel R
- Katayama, Ryohei
- Costa, Carlotta
- Ross, Kenneth N
- Moran, Teresa
- Howe, Emily
- Fulton, Linnea E
- Mulvey, Hillary E
- Bernardo, Lindsay A
- Mohamoud, Farhiya
- Miyoshi, Norikatsu
- VanderLaan, Paul A
- Costa, Daniel B
- Jänne, Pasi A
- Borger, Darrell R
- Ramaswamy, Sridhar
- Shioda, Toshi
- Iafrate, Anthony J
- Getz, Gad
- Rudin, Charles M
- Mino-Kenudson, Mari
- Engelman, Jeffrey A
Producer: 20160209
In:
Nature communications vol. 6
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700.
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From Diagnostic-Therapeutic Pathways to Real-World Data: A Multicenter Prospective Study on Upfront Treatment for [electronic resource] by
- Pasello, Giulia
- Vicario, Giovanni
- Zustovich, Fable
- Oniga, Francesco
- Gori, Stefania
- Rosetti, Francesco
- Bonetti, Andrea
- Favaretto, Adolfo
- Toso, Silvia
- Redelotti, Roberta
- Santo, Antonio
- Bernardi, Daniele
- Giovanis, Petros
- Oliani, Cristina
- Calvetti, Lorenzo
- Gatti, Carlo
- Palazzolo, Giovanni
- Baretta, Zora
- Bortolami, Alberto
- Bonanno, Laura
- Basso, Marco
- Menis, Jessica
- Corte, Donatella Da
- Frega, Stefano
- Guarneri, Valentina
- Conte, PierFranco
Producer: 20200720
In:
The oncologist vol. 24
Availability: No items available.
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