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	61.	Catalytic mechanism of the cyclohydrolase activity of human aminoimidazole carboxamide ribonucleotide formyltransferase/inosine monophosphate cyclohydrolase. [electronic resource] by Vergis, James M Beardsley, G Peter Producer: 20040608 In: Biochemistry vol. 43 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	62.	Synthesis and biological activity of an acyclic analogue of 5,6,7,8-tetrahydrofolic acid, N-[4-[[3-(2,4-diamino-1,6-dihydro-6-oxo-5- pyrimidinyl)propyl]amino]-benzoyl]-L-glutamic acid. [electronic resource] by Kelley, J L McLean, E W Cohn, N K Edelstein, M P Duch, D S Smith, G K Hanlon, M H Ferone, R Producer: 19900309 In: Journal of medicinal chemistry vol. 33 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	63.	Dual effects of pyrazofurin and 3-deazauridine upon pyrimidine and purine biosynthesis in mouse L1210 leukemia. [electronic resource] by Sant, M E Lyons, S D Kemp, A J McClure, L K Szabados, E Christopherson, R I Producer: 19890612 In: Cancer research vol. 49 Availability: No items available. Save to lists Add to cart (remove)
	64.	Evidence that the folate-requiring enzymes of de novo purine biosynthesis are encoded by individual mRNAs. [electronic resource] by Wasserman, G F Mueller, W T Benkovic, S J Liao, W S Taylor, J Producer: 19850429 In: Biochemistry vol. 23 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	65.	AICA-ribosiduria: a novel, neurologically devastating inborn error of purine biosynthesis caused by mutation of ATIC. [electronic resource] by Marie, Sandrine Heron, Benedicte Bitoun, Pierre Timmerman, Therese Van Den Berghe, Georges Vincent, Marie-Francoise Producer: 20040706 In: American journal of human genetics vol. 74 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	66.	Synthesis and biological evaluation of N-[4-[5-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-2-(2,2,2-trifluoroacetyl)pentyl]benzoyl]-L-glutamic acid as a potential inhibitor of GAR Tfase and the de novo purine biosynthetic pathway. [electronic resource] by Cheng, Heng Hwang, Inkyu Chong, Youhoon Tavassoli, Ali Webb, Michael E Zhang, Yan Wilson, Ian A Benkovic, Stephen J Boger, Dale L Producer: 20050908 In: Bioorganic & medicinal chemistry vol. 13 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	67.	Discovery of N-(6-Fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)-5-[(3R)-3-hydroxypyrrolidin-1-yl]thiophene-2-sulfonamide (LSN 3213128), a Potent and Selective Nonclassical Antifolate Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase (AICARFT) Inhibitor Effective at Tumor Suppression in a Cancer Xenograft Model. [electronic resource] by Fales, Kevin R Njoroge, F George Brooks, Harold B Thibodeaux, Stefan Torrado, Alicia Si, Chong Toth, James L Mc Cowan, Jefferson R Roth, Kenneth D Thrasher, Kenneth J Frimpong, Kwame Lee, Matthew R Dally, Robert D Shepherd, Timothy A Durham, Timothy B Margolis, Brandon J Wu, Zhipei Wang, Yong Atwell, Shane Wang, Jing Hui, Yu-Hua Meier, Timothy I Konicek, Susan A Geeganage, Sandaruwan Producer: 20171229 In: Journal of medicinal chemistry vol. 60 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	68.	Methotrexate and erythro-9-(2-hydroxynon-3-yl) adenine therapy for rat adjuvant arthritis and the effect of methotrexate on in vivo purine metabolism. [electronic resource] by Baggott, Joseph E Morgan, Sarah L Producer: 20070817 In: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences vol. 31 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	69.	Novel 6-substituted benzoyl and non-benzoyl straight chain pyrrolo[2,3-d]pyrimidines as potential antitumor agents with multitargeted inhibition of TS, GARFTase and AICARFTase. [electronic resource] by Xing, Ruijuan Zhang, Hongying Yuan, Jiangsong Zhang, Kai Li, Lin Guo, Huicai Zhao, Lijuan Zhang, Congying Li, Shuolei Gao, Tianfeng Liu, Yi Wang, Lei Producer: 20171016 In: European journal of medicinal chemistry vol. 139 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	70.	Design, synthesis, and biological evaluation of 10-methanesulfonyl-DDACTHF, 10-methanesulfonyl-5-DACTHF, and 10-methylthio-DDACTHF as potent inhibitors of GAR Tfase and the de novo purine biosynthetic pathway. [electronic resource] by Cheng, Heng Chong, Youhoon Hwang, Inkyu Tavassoli, Ali Zhang, Yan Wilson, Ian A Benkovic, Stephen J Boger, Dale L Producer: 20050908 In: Bioorganic & medicinal chemistry vol. 13 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	71.	The antiinflammatory effects of methotrexate are mediated by adenosine. [electronic resource] by Cronstein, B N Naime, D Ostad, E Producer: 19951002 In: Advances in experimental medicine and biology vol. 370 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	72.	10-Formyl-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid (10-formyl-DDACTHF): a potent cytotoxic agent acting by selective inhibition of human GAR Tfase and the de novo purine biosynthetic pathway. [electronic resource] by Marsilje, Thomas H Labroli, Marc A Hedrick, Michael P Jin, Qing Desharnais, Joel Baker, Stephen J Gooljarsingh, Lata T Ramcharan, Joseph Tavassoli, Ali Zhang, Yan Wilson, Ian A Beardsley, G Peter Benkovic, Stephen J Boger, Dale L Producer: 20030731 In: Bioorganic & medicinal chemistry vol. 10 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	73.	The phosphatidylinositol 3-kinase/akt cassette regulates purine nucleotide synthesis. [electronic resource] by Wang, Wei Fridman, Alla Blackledge, William Connelly, Stephen Wilson, Ian A Pilz, Renate B Boss, Gerry R Producer: 20090406 In: The Journal of biological chemistry vol. 284 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	74.	Inhibition of folate-dependent enzymes by non-steroidal anti-inflammatory drugs. [electronic resource] by Baggott, J E Morgan, S L Ha, T Vaughn, W H Hine, R J Producer: 19920331 In: The Biochemical journal vol. 282 ( Pt 1) Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	75.	De novo purine nucleotide biosynthesis: cloning, sequencing and expression of a chicken PurH cDNA encoding 5-aminoimidazole-4-carboxamide-ribonucleotide transformylase-IMP cyclohydrolase. [electronic resource] by Ni, L Guan, K Zalkin, H Dixon, J E Producer: 19911223 In: Gene vol. 106 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	76.	Update on antifolate drugs targets. [electronic resource] by Costi, M P Ferrari, S Producer: 20011018 In: Current drug targets vol. 2 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	77.	Purine biosynthesis in Escherichia coli K12: structure and DNA sequence studies of the purHD locus. [electronic resource] by Flannigan, K A Hennigan, S H Vogelbacker, H H Gots, J S Smith, J M Producer: 19900726 In: Molecular microbiology vol. 4 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	78.	Conserved arrangement of nested genes at the Drosophila Gart locus. [electronic resource] by Henikoff, S Eghtedarzadeh, M K Producer: 19880308 In: Genetics vol. 117 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	79.	A mathematical model gives insights into nutritional and genetic aspects of folate-mediated one-carbon metabolism. [electronic resource] by Reed, Michael C Nijhout, H Frederik Neuhouser, Marian L Gregory, Jesse F Shane, Barry James, S Jill Boynton, Alanna Ulrich, Cornelia M Producer: 20061027 In: The Journal of nutrition vol. 136 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	80.	Novel 5-substituted pyrrolo[2,3-d]pyrimidines as dual inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase and as potential antitumor agents. [electronic resource] by Wang, Yiqiang Mitchell-Ryan, Shermaine Raghavan, Sudhir George, Christina Orr, Steven Hou, Zhanjun Matherly, Larry H Gangjee, Aleem Producer: 20150414 In: Journal of medicinal chemistry vol. 58 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)

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Your search returned 107 results.