Results
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61.
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Structural characterization of HIV reverse transcriptase: a target for the design of specific virus inhibitors. [electronic resource] by
- Tisdale, M
- Larder, B A
- Lowe, D M
- Stammers, D K
- Purifoy, D J
- Ertl, P
- Bradley, C
- Kemp, S
- Darby, G K
- Powell, K L
Producer: 19890613
In:
The Journal of antimicrobial chemotherapy vol. 23 Suppl A
Availability: No items available.
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62.
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Biaryl acids: novel non-nucleoside inhibitors of HIV reverse transcriptase types 1 and 2. [electronic resource] by
- Milton, J
- Slater, M J
- Bird, A J
- Spinks, D
- Scott, G
- Price, C E
- Downing, S
- Green, D V
- Madar, S
- Bethell, R
- Stammers, D K
Producer: 19990202
In:
Bioorganic & medicinal chemistry letters vol. 8
Availability: No items available.
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63.
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3'-Azido-3'-deoxythymidine drug resistance mutations in HIV-1 reverse transcriptase can induce long range conformational changes. [electronic resource] by
- Ren, J
- Esnouf, R M
- Hopkins, A L
- Jones, E Y
- Kirby, I
- Keeling, J
- Ross, C K
- Larder, B A
- Stuart, D I
- Stammers, D K
Producer: 19980908
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 95
Availability: No items available.
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64.
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Allosteric inhibitors against HIV-1 reverse transcriptase: design and synthesis of MKC-442 analogues having an omega-functionalized acyclic structure. [electronic resource] by
- Tanaka, H
- Walker, R T
- Hopkins, A L
- Ren, J
- Jones, E Y
- Fujimoto, K
- Hayashi, M
- Miyasaka, T
- Baba, M
- Stammers, D K
- Stuart, D I
Producer: 19990210
In:
Antiviral chemistry & chemotherapy vol. 9
Availability: No items available.
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65.
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Receptor-based design of dihydrofolate reductase inhibitors: comparison of crystallographically determined enzyme binding with enzyme affinity in a series of carboxy-substituted trimethoprim analogues. [electronic resource] by
- Kuyper, L F
- Roth, B
- Baccanari, D P
- Ferone, R
- Beddell, C R
- Champness, J N
- Stammers, D K
- Dann, J G
- Norrington, F E
- Baker, D J
Producer: 19850412
In:
Journal of medicinal chemistry vol. 28
Availability: No items available.
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66.
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Crystals of HIV-1 reverse transcriptase diffracting to 2.2 A resolution. [electronic resource] by
- Stammers, D K
- Somers, D O
- Ross, C K
- Kirby, I
- Ray, P H
- Wilson, J E
- Norman, M
- Ren, J S
- Esnouf, R M
- Garman, E F
Producer: 19941102
In:
Journal of molecular biology vol. 242
Availability: No items available.
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67.
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Complexes of HIV-1 reverse transcriptase with inhibitors of the HEPT series reveal conformational changes relevant to the design of potent non-nucleoside inhibitors. [electronic resource] by
- Hopkins, A L
- Ren, J
- Esnouf, R M
- Willcox, B E
- Jones, E Y
- Ross, C
- Miyasaka, T
- Walker, R T
- Tanaka, H
- Stammers, D K
- Stuart, D I
Producer: 19960725
In:
Journal of medicinal chemistry vol. 39
Availability: No items available.
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68.
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Refined crystal structures of Escherichia coli and chicken liver dihydrofolate reductase containing bound trimethoprim. [electronic resource] by
- Matthews, D A
- Bolin, J T
- Burridge, J M
- Filman, D J
- Volz, K W
- Kaufman, B T
- Beddell, C R
- Champness, J N
- Stammers, D K
- Kraut, J
Producer: 19850215
In:
The Journal of biological chemistry vol. 260
Availability: No items available.
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69.
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A family of insertion mutations between codons 67 and 70 of human immunodeficiency virus type 1 reverse transcriptase confer multinucleoside analog resistance. [electronic resource] by
- Larder, B A
- Bloor, S
- Kemp, S D
- Hertogs, K
- Desmet, R L
- Miller, V
- Sturmer, M
- Staszewski, S
- Ren, J
- Stammers, D K
- Stuart, D I
- Pauwels, R
Producer: 19990909
In:
Antimicrobial agents and chemotherapy vol. 43
Availability: No items available.
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70.
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Receptor-based design of dihydrofolate reductase inhibitors: comparison of crystallographically determined enzyme binding with enzyme affinity in a series of carboxy-substituted trimethoprim analogues. [electronic resource] by
- Kuyper, L F
- Roth, B
- Baccanari, D P
- Ferone, R
- Beddell, C R
- Champness, J N
- Stammers, D K
- Dann, J G
- Norrington, F E
- Baker, D J
- Goodford, P J
Producer: 19830107
In:
Journal of medicinal chemistry vol. 25
Availability: No items available.
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71.
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2-Amino-6-arylsulfonylbenzonitriles as non-nucleoside reverse transcriptase inhibitors of HIV-1. [electronic resource] by
- Chan, J H
- Hong, J S
- Hunter , R N
- Orr, G F
- Cowan, J R
- Sherman, D B
- Sparks, S M
- Reitter, B E
- Andrews , C W
- Hazen, R J
- St Clair, M
- Boone, L R
- Ferris, R G
- Creech, K L
- Roberts, G B
- Short, S A
- Weaver, K
- Ott, R J
- Ren, J
- Hopkins, A
- Stuart, D I
- Stammers, D K
Producer: 20010628
In:
Journal of medicinal chemistry vol. 44
Availability: No items available.
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