Results
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61.
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An exocyclic methylene group acts as a bioisostere of the 2'-oxygen atom in LNA. [electronic resource] by
- Seth, Punit P
- Allerson, Charles R
- Berdeja, Andres
- Siwkowski, Andrew
- Pallan, Pradeep S
- Gaus, Hans
- Prakash, Thazha P
- Watt, Andrew T
- Egli, Martin
- Swayze, Eric E
Producer: 20110203
In:
Journal of the American Chemical Society vol. 132
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62.
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Design, synthesis and evaluation of constrained methoxyethyl (cMOE) and constrained ethyl (cEt) nucleoside analogs. [electronic resource] by
- Seth, Punit P
- Siwkowski, Andrew
- Allerson, Charles R
- Vasquez, Guillermo
- Lee, Sam
- Prakash, Thazha P
- Kinberger, Garth
- Migawa, Michael T
- Gaus, Hans
- Bhat, Balkrishen
- Swayze, Eric E
Producer: 20101116
In:
Nucleic acids symposium series (2004) no. 52
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63.
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Conjugation of mono and di-GalNAc sugars enhances the potency of antisense oligonucleotides via ASGR mediated delivery to hepatocytes. [electronic resource] by
- Kinberger, Garth A
- Prakash, Thazha P
- Yu, Jinghua
- Vasquez, Guillermo
- Low, Audrey
- Chappell, Alfred
- Schmidt, Karsten
- Murray, Heather M
- Gaus, Hans
- Swayze, Eric E
- Seth, Punit P
Producer: 20170620
In:
Bioorganic & medicinal chemistry letters vol. 26
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64.
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Characterizing the effect of GalNAc and phosphorothioate backbone on binding of antisense oligonucleotides to the asialoglycoprotein receptor. [electronic resource] by
- Schmidt, Karsten
- Prakash, Thazha P
- Donner, Aaron J
- Kinberger, Garth A
- Gaus, Hans J
- Low, Audrey
- Østergaard, Michael E
- Bell, Melanie
- Swayze, Eric E
- Seth, Punit P
Producer: 20170718
In:
Nucleic acids research vol. 45
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65.
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Synthesis, improved antisense activity and structural rationale for the divergent RNA affinities of 3'-fluoro hexitol nucleic acid (FHNA and Ara-FHNA) modified oligonucleotides. [electronic resource] by
- Egli, Martin
- Pallan, Pradeep S
- Allerson, Charles R
- Prakash, Thazha P
- Berdeja, Andres
- Yu, Jinghua
- Lee, Sam
- Watt, Andrew
- Gaus, Hans
- Bhat, Balkrishen
- Swayze, Eric E
- Seth, Punit P
Producer: 20120203
In:
Journal of the American Chemical Society vol. 133
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66.
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Identification of metabolically stable 5΄-phosphate analogs that support single-stranded siRNA activity. [electronic resource] by
- Prakash, Thazha P
- Lima, Walt F
- Murray, Heather M
- Li, Wenyu
- Kinberger, Garth A
- Chappell, Alfred E
- Gaus, Hans
- Seth, Punit P
- Bhat, Balkrishen
- Crooke, Stanley T
- Swayze, Eric E
Publication details: Nucleic acids research 06 2017
In:
Nucleic acids research vol. 45
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67.
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Identification of metabolically stable 5'-phosphate analogs that support single-stranded siRNA activity. [electronic resource] by
- Prakash, Thazha P
- Lima, Walt F
- Murray, Heather M
- Li, Wenyu
- Kinberger, Garth A
- Chappell, Alfred E
- Gaus, Hans
- Seth, Punit P
- Bhat, Balkrishen
- Crooke, Stanley T
- Swayze, Eric E
Producer: 20150626
In:
Nucleic acids research vol. 43
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68.
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Novel Targeted Therapy for Precursor B Cell Acute Lymphoblastic Leukemia: anti-CD22 Antibody-MXD3 Antisense Oligonucleotide Conjugate. [electronic resource] by
- Satake, Noriko
- Duong, Connie
- Yoshida, Sakiko
- Oestergaard, Michael
- Chen, Cathy
- Peralta, Rachael
- Guo, Shuling
- Seth, Punit P
- Li, Yueju
- Beckett, Laurel
- Chung, Jong
- Nolta, Jan
- Nitin, Nitin
- Tuscano, Joseph M
Publication details: Molecular medicine (Cambridge, Mass.) Oct 2016
In:
Molecular medicine (Cambridge, Mass.) vol. 22
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69.
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Solid-phase synthesis of 5'-triantennary N-acetylgalactosamine conjugated antisense oligonucleotides using phosphoramidite chemistry. [electronic resource] by
- Prakash, Thazha P
- Brad Wan, W
- Low, Audrey
- Yu, Jinghua
- Chappell, Alfred E
- Gaus, Hans
- Kinberger, Garth A
- Østergaard, Michael E
- Migawa, Michael T
- Swayze, Eric E
- Seth, Punit P
Producer: 20160523
In:
Bioorganic & medicinal chemistry letters vol. 25
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70.
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Synthesis, biophysical properties and biological activity of second generation antisense oligonucleotides containing chiral phosphorothioate linkages. [electronic resource] by
- Wan, W Brad
- Migawa, Michael T
- Vasquez, Guillermo
- Murray, Heather M
- Nichols, Josh G
- Gaus, Hans
- Berdeja, Andres
- Lee, Sam
- Hart, Christopher E
- Lima, Walt F
- Swayze, Eric E
- Seth, Punit P
Producer: 20150512
In:
Nucleic acids research vol. 42
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71.
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Fatty acid conjugation enhances potency of antisense oligonucleotides in muscle. [electronic resource] by
- Prakash, Thazha P
- Mullick, Adam E
- Lee, Richard G
- Yu, Jinghua
- Yeh, Steve T
- Low, Audrey
- Chappell, Alfred E
- Østergaard, Michael E
- Murray, Sue
- Gaus, Hans J
- Swayze, Eric E
- Seth, Punit P
Producer: 20200225
In:
Nucleic acids research vol. 47
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72.
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SAR by MS: discovery of a new class of RNA-binding small molecules for the hepatitis C virus: internal ribosome entry site IIA subdomain. [electronic resource] by
- Seth, Punit P
- Miyaji, Alycia
- Jefferson, Elizabeth A
- Sannes-Lowery, Kristin A
- Osgood, Stephen A
- Propp, Stephanie S
- Ranken, Ray
- Massire, Christian
- Sampath, Rangarajan
- Ecker, David J
- Swayze, Eric E
- Griffey, Richard H
Producer: 20060117
In:
Journal of medicinal chemistry vol. 48
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73.
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Rational design of antisense oligonucleotides targeting single nucleotide polymorphisms for potent and allele selective suppression of mutant Huntingtin in the CNS. [electronic resource] by
- Østergaard, Michael E
- Southwell, Amber L
- Kordasiewicz, Holly
- Watt, Andrew T
- Skotte, Niels H
- Doty, Crystal N
- Vaid, Kuljeet
- Villanueva, Erika B
- Swayze, Eric E
- Bennett, C Frank
- Hayden, Michael R
- Seth, Punit P
Producer: 20140122
In:
Nucleic acids research vol. 41
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74.
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Single-stranded siRNAs activate RNAi in animals. [electronic resource] by
- Lima, Walt F
- Prakash, Thazha P
- Murray, Heather M
- Kinberger, Garth A
- Li, Wenyu
- Chappell, Alfred E
- Li, Cheryl S
- Murray, Susan F
- Gaus, Hans
- Seth, Punit P
- Swayze, Eric E
- Crooke, Stanley T
Producer: 20121105
In:
Cell vol. 150
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75.
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Elucidation of the Biotransformation Pathways of a Galnac3-conjugated Antisense Oligonucleotide in Rats and Monkeys. [electronic resource] by
- Shemesh, Colby S
- Yu, Rosie Z
- Gaus, Hans J
- Greenlee, Sarah
- Post, Noah
- Schmidt, Karsten
- Migawa, Michael T
- Seth, Punit P
- Zanardi, Thomas A
- Prakash, Thazha P
- Swayze, Eric E
- Henry, Scott P
- Wang, Yanfeng
Producer: 20160511
In:
Molecular therapy. Nucleic acids vol. 5
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76.
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Disposition and Pharmacology of a GalNAc3-conjugated ASO Targeting Human Lipoprotein (a) in Mice. [electronic resource] by
- Yu, Rosie Z
- Graham, Mark J
- Post, Noah
- Riney, Stan
- Zanardi, Thomas
- Hall, Shannon
- Burkey, Jennifer
- Shemesh, Colby S
- Prakash, Thazha P
- Seth, Punit P
- Swayze, Eric E
- Geary, Richard S
- Wang, Yanfeng
- Henry, Scott
Producer: 20160504
In:
Molecular therapy. Nucleic acids vol. 5
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77.
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Efficient Synthesis and Biological Evaluation of 5'-GalNAc Conjugated Antisense Oligonucleotides. [electronic resource] by
- Østergaard, Michael E
- Yu, Jinghua
- Kinberger, Garth A
- Wan, W Brad
- Migawa, Michael T
- Vasquez, Guillermo
- Schmidt, Karsten
- Gaus, Hans J
- Murray, Heather M
- Low, Audrey
- Swayze, Eric E
- Prakash, Thazha P
- Seth, Punit P
Producer: 20160519
In:
Bioconjugate chemistry vol. 26
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78.
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Understanding the effect of controlling phosphorothioate chirality in the DNA gap on the potency and safety of gapmer antisense oligonucleotides. [electronic resource] by
- Østergaard, Michael E
- De Hoyos, Cheryl L
- Wan, W Brad
- Shen, Wen
- Low, Audrey
- Berdeja, Andres
- Vasquez, Guillermo
- Murray, Susan
- Migawa, Michael T
- Liang, Xue-Hai
- Swayze, Eric E
- Crooke, Stanley T
- Seth, Punit P
Producer: 20200330
In:
Nucleic acids research vol. 48
Availability: No items available.
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79.
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Disposition and Pharmacokinetics of a GalNAc3-Conjugated Antisense Oligonucleotide Targeting Human Lipoprotein (a) in Monkeys. [electronic resource] by
- Yu, Rosie Z
- Gunawan, Rudy
- Post, Noah
- Zanardi, Thomas
- Hall, Shannon
- Burkey, Jennifer
- Kim, Tae-Won
- Graham, Mark J
- Prakash, Thazha P
- Seth, Punit P
- Swayze, Eric E
- Geary, Richard S
- Henry, Scott P
- Wang, Yanfeng
Producer: 20171110
In:
Nucleic acid therapeutics vol. 26
Availability: No items available.
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80.
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In vivo evaluation of candidate allele-specific mutant huntingtin gene silencing antisense oligonucleotides. [electronic resource] by
- Southwell, Amber L
- Skotte, Niels H
- Kordasiewicz, Holly B
- Østergaard, Michael E
- Watt, Andrew T
- Carroll, Jeffrey B
- Doty, Crystal N
- Villanueva, Erika B
- Petoukhov, Eugenia
- Vaid, Kuljeet
- Xie, Yuanyun
- Freier, Susan M
- Swayze, Eric E
- Seth, Punit P
- Bennett, Clarence Frank
- Hayden, Michael R
Producer: 20151022
In:
Molecular therapy : the journal of the American Society of Gene Therapy vol. 22
Availability: No items available.
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