Results
|
|
61.
|
APH1 polar transmembrane residues regulate the assembly and activity of presenilin complexes. [electronic resource] by
- Pardossi-Piquard, Raphaëlle
- Yang, Seung-Pil
- Kanemoto, Soshi
- Gu, Yongjun
- Chen, Fusheng
- Böhm, Christopher
- Sevalle, Jean
- Li, Tong
- Wong, Philip C
- Checler, Frédéric
- Schmitt-Ulms, Gerold
- St George-Hyslop, Peter
- Fraser, Paul E
Producer: 20090820
In:
The Journal of biological chemistry vol. 284
Availability: No items available.
|
|
|
62.
|
Early fear memory defects are associated with altered synaptic plasticity and molecular architecture in the TgCRND8 Alzheimer's disease mouse model. [electronic resource] by
- Steele, John W
- Brautigam, Hannah
- Short, Jennifer A
- Sowa, Allison
- Shi, Mengxi
- Yadav, Aniruddha
- Weaver, Christina M
- Westaway, David
- Fraser, Paul E
- St George-Hyslop, Peter H
- Gandy, Sam
- Hof, Patrick R
- Dickstein, Dara L
Producer: 20141209
In:
The Journal of comparative neurology vol. 522
Availability: No items available.
|
|
|
63.
|
Interactome analyses of mature γ-secretase complexes reveal distinct molecular environments of presenilin (PS) paralogs and preferential binding of signal peptide peptidase to PS2. [electronic resource] by
- Jeon, Amy Hye Won
- Böhm, Christopher
- Chen, Fusheng
- Huo, Hairu
- Ruan, Xueying
- Ren, Carl He
- Ho, Keith
- Qamar, Seema
- Mathews, Paul M
- Fraser, Paul E
- Mount, Howard T J
- St George-Hyslop, Peter
- Schmitt-Ulms, Gerold
Producer: 20130805
In:
The Journal of biological chemistry vol. 288
Availability: No items available.
|
|
|
64.
|
Amyloid-beta42 signals tau hyperphosphorylation and compromises neuronal viability by disrupting alkylacylglycerophosphocholine metabolism. [electronic resource] by
- Ryan, Scott D
- Whitehead, Shawn N
- Swayne, Leigh Anne
- Moffat, Tia C
- Hou, Weimin
- Ethier, Martin
- Bourgeois, André J G
- Rashidian, Juliet
- Blanchard, Alexandre P
- Fraser, Paul E
- Park, David S
- Figeys, Daniel
- Bennett, Steffany A L
Producer: 20100908
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 106
Availability: No items available.
|
|
|
65.
|
Alzheimer amyloid peptide aβ42 regulates gene expression of transcription and growth factors. [electronic resource] by
- Barucker, Christian
- Sommer, Anette
- Beckmann, Georg
- Eravci, Murat
- Harmeier, Anja
- Schipke, Carola G
- Brockschnieder, Damian
- Dyrks, Thomas
- Althoff, Veit
- Fraser, Paul E
- Hazrati, Lili-Naz
- George-Hyslop, Peter St
- Breitner, John C S
- Peters, Oliver
- Multhaup, Gerhard
Producer: 20150921
In:
Journal of Alzheimer's disease : JAD vol. 44
Availability: No items available.
|
|
|
66.
|
Genetic mapping of activity determinants within cellular prion proteins: N-terminal modules in PrPC offset pro-apoptotic activity of the Doppel helix B/B' region. [electronic resource] by
- Drisaldi, Bettina
- Coomaraswamy, Janaky
- Mastrangelo, Peter
- Strome, Bob
- Yang, Jing
- Watts, Joel C
- Chishti, M Azhar
- Marvi, Melissa
- Windl, Otto
- Ahrens, Rosemary
- Major, François
- Sy, Man-Sun
- Kretzschmar, Hans
- Fraser, Paul E
- Mount, Howard T J
- Westaway, David
Producer: 20050225
In:
The Journal of biological chemistry vol. 279
Availability: No items available.
|
|
|
67.
|
The CNS glycoprotein Shadoo has PrP(C)-like protective properties and displays reduced levels in prion infections. [electronic resource] by
- Watts, Joel C
- Drisaldi, Bettina
- Ng, Vivian
- Yang, Jing
- Strome, Bob
- Horne, Patrick
- Sy, Man-Sun
- Yoong, Larry
- Young, Rebecca
- Mastrangelo, Peter
- Bergeron, Catherine
- Fraser, Paul E
- Carlson, George A
- Mount, Howard T J
- Schmitt-Ulms, Gerold
- Westaway, David
Producer: 20071030
In:
The EMBO journal vol. 26
Availability: No items available.
|
|
|
68.
|
Expression of the Alzheimer's Disease Mutations AβPP695sw and PSEN1M146I in Double-Transgenic Göttingen Minipigs. [electronic resource] by
- Jakobsen, Jannik E
- Johansen, Marianne G
- Schmidt, Mette
- Liu, Ying
- Li, Rong
- Callesen, Henrik
- Melnikova, Margarita
- Habekost, Mette
- Matrone, Carmela
- Bouter, Yvonne
- Bayer, Thomas A
- Nielsen, Anders Lade
- Duthie, Monika
- Fraser, Paul E
- Holm, Ida E
- Jørgensen, Arne Lund
Producer: 20180129
In:
Journal of Alzheimer's disease : JAD vol. 53
Availability: No items available.
|
|
|
69.
|
Presenilin 1 and presenilin 2 have differential effects on the stability and maturation of nicastrin in Mammalian brain. [electronic resource] by
- Chen, Fusheng
- Tandon, Anurag
- Sanjo, Nobuo
- Gu, Yong-Jun
- Hasegawa, Hiroshi
- Arawaka, Shigeki
- Lee, Frank J S
- Ruan, Xueying
- Mastrangelo, Peter
- Erdebil, Serap
- Wang, Linda
- Westaway, David
- Mount, Howard T J
- Yankner, Bruce
- Fraser, Paul E
- St George-Hyslop, Peter
Producer: 20030710
In:
The Journal of biological chemistry vol. 278
Availability: No items available.
|
|
|
70.
|
Mature glycosylation and trafficking of nicastrin modulate its binding to presenilins. [electronic resource] by
- Yang, Dun-Sheng
- Tandon, Anurag
- Chen, Fusheng
- Yu, Gang
- Yu, Haung
- Arawaka, Shigeki
- Hasegawa, Hiroshi
- Duthie, Monika
- Schmidt, Stephen D
- Ramabhadran, Triprayer V
- Nixon, Ralph A
- Mathews, Paul M
- Gandy, Samuel E
- Mount, Howard T J
- St George-Hyslop, Peter
- Fraser, Paul E
Producer: 20020916
In:
The Journal of biological chemistry vol. 277
Availability: No items available.
|
|
|
71.
|
Alzheimer amyloid precursor aspartyl proteinase activity in CHAPSO homogenates of Spodoptera frugiperda cells. [electronic resource] by
- Carter, Troy L
- Verdile, Giuseppe
- Groth, David
- Bogush, Alexey
- Thomas, Stefani
- Shen, Patrick
- Fraser, Paul E
- Mathews, Paul
- Nixon, Ralph A
- Ehrlich, Michelle E
- Kwok, John B J
- St George-Hyslop, Peter
- Schofield, Peter
- Li, Yueming
- Yang, Austin
- Martins, Ralph N
- Gandy, Sam
Producer: 20050405
In:
Alzheimer disease and associated disorders vol. 18
Availability: No items available.
|
|
|
72.
|
TgCRND8 amyloid precursor protein transgenic mice exhibit an altered gamma-secretase processing and an aggressive, additive amyloid pathology subject to immunotherapeutic modulation. [electronic resource] by
- Van Vickle, Gregory D
- Esh, Chera L
- Kalback, Walter M
- Patton, R Lyle
- Luehrs, Dean C
- Kokjohn, Tyler A
- Fifield, Frederick G
- Fraser, Paul E
- Westaway, David
- McLaurin, Joanne
- Lopez, John
- Brune, Daniel
- Newel, Amanda J
- Poston, Marissa
- Beach, Thomas G
- Roher, Alex E
Producer: 20071010
In:
Biochemistry vol. 46
Availability: No items available.
|
|
|
73.
|
Cyclohexanehexol inhibitors of Abeta aggregation prevent and reverse Alzheimer phenotype in a mouse model. [electronic resource] by
- McLaurin, JoAnne
- Kierstead, Meredith E
- Brown, Mary E
- Hawkes, Cheryl A
- Lambermon, Mark H L
- Phinney, Amie L
- Darabie, Audrey A
- Cousins, Julian E
- French, Janet E
- Lan, Melissa F
- Chen, Fusheng
- Wong, Sydney S N
- Mount, Howard T J
- Fraser, Paul E
- Westaway, David
- St George-Hyslop, Peter
Producer: 20060914
In:
Nature medicine vol. 12
Availability: No items available.
|
|
|
74.
|
Dissociated phenotypes in presenilin transgenic mice define functionally distinct gamma-secretases. [electronic resource] by
- Mastrangelo, Peter
- Mathews, Paul M
- Chishti, M Azhar
- Schmidt, Stephen D
- Gu, Yongjun
- Yang, Jing
- Mazzella, Matthew J
- Coomaraswamy, Janaky
- Horne, Patrick
- Strome, Bob
- Pelly, Heather
- Levesque, Georges
- Ebeling, Chris
- Jiang, Ying
- Nixon, Ralph A
- Rozmahel, Richard
- Fraser, Paul E
- St George-Hyslop, Peter
- Carlson, George A
- Westaway, David
Producer: 20050901
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 102
Availability: No items available.
|
|
|
75.
|
Insulin resistance is associated with reductions in specific cognitive domains and increases in CSF tau in cognitively normal adults. [electronic resource] by
- Laws, Simon M
- Gaskin, Scott
- Woodfield, Amy
- Srikanth, Velandai
- Bruce, David
- Fraser, Paul E
- Porter, Tenielle
- Newsholme, Philip
- Wijesekara, Nadeeja
- Burnham, Samantha
- Doré, Vincent
- Li, Qiao-Xin
- Maruff, Paul
- Masters, Colin L
- Rainey-Smith, Stephanie
- Rowe, Christopher C
- Salvado, Olivier
- Villemagne, Victor L
- Martins, Ralph N
- Verdile, Giuseppe
Producer: 20190415
In:
Scientific reports vol. 7
Availability: No items available.
|
|
|
76.
|
Structural interactions between inhibitor and substrate docking sites give insight into mechanisms of human PS1 complexes. [electronic resource] by
- Li, Yi
- Lu, Stephen Hsueh-Jeng
- Tsai, Ching-Ju
- Bohm, Christopher
- Qamar, Seema
- Dodd, Roger B
- Meadows, William
- Jeon, Amy
- McLeod, Adam
- Chen, Fusheng
- Arimon, Muriel
- Berezovska, Oksana
- Hyman, Bradley T
- Tomita, Taisuke
- Iwatsubo, Takeshi
- Johnson, Christopher M
- Farrer, Lindsay A
- Schmitt-Ulms, Gerold
- Fraser, Paul E
- St George-Hyslop, Peter H
Producer: 20140825
In:
Structure (London, England : 1993) vol. 22
Availability: No items available.
|
|
|
77.
|
α-Synuclein strains target distinct brain regions and cell types. [electronic resource] by
- Lau, Angus
- So, Raphaella W L
- Lau, Heather H C
- Sang, Jason C
- Ruiz-Riquelme, Alejandro
- Fleck, Shelaine C
- Stuart, Erica
- Menon, Sindhu
- Visanji, Naomi P
- Meisl, Georg
- Faidi, Rania
- Marano, Maria M
- Schmitt-Ulms, Cian
- Wang, Zhilan
- Fraser, Paul E
- Tandon, Anurag
- Hyman, Bradley T
- Wille, Holger
- Ingelsson, Martin
- Klenerman, David
- Watts, Joel C
Producer: 20200413
In:
Nature neuroscience vol. 23
Availability: No items available.
|
|
|
78.
|
FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions. [electronic resource] by
- Qamar, Seema
- Wang, GuoZhen
- Randle, Suzanne J
- Ruggeri, Francesco Simone
- Varela, Juan A
- Lin, Julie Qiaojin
- Phillips, Emma C
- Miyashita, Akinori
- Williams, Declan
- Ströhl, Florian
- Meadows, William
- Ferry, Rodylyn
- Dardov, Victoria J
- Tartaglia, Gian G
- Farrer, Lindsay A
- Kaminski Schierle, Gabriele S
- Kaminski, Clemens F
- Holt, Christine E
- Fraser, Paul E
- Schmitt-Ulms, Gerold
- Klenerman, David
- Knowles, Tuomas
- Vendruscolo, Michele
- St George-Hyslop, Peter
Producer: 20190211
In:
Cell vol. 173
Availability: No items available.
|
|
|
79.
|
ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function. [electronic resource] by
- Murakami, Tetsuro
- Qamar, Seema
- Lin, Julie Qiaojin
- Schierle, Gabriele S Kaminski
- Rees, Eric
- Miyashita, Akinori
- Costa, Ana R
- Dodd, Roger B
- Chan, Fiona T S
- Michel, Claire H
- Kronenberg-Versteeg, Deborah
- Li, Yi
- Yang, Seung-Pil
- Wakutani, Yosuke
- Meadows, William
- Ferry, Rodylyn Rose
- Dong, Liang
- Tartaglia, Gian Gaetano
- Favrin, Giorgio
- Lin, Wen-Lang
- Dickson, Dennis W
- Zhen, Mei
- Ron, David
- Schmitt-Ulms, Gerold
- Fraser, Paul E
- Shneider, Neil A
- Holt, Christine
- Vendruscolo, Michele
- Kaminski, Clemens F
- St George-Hyslop, Peter
Producer: 20160301
In:
Neuron vol. 88
Availability: No items available.
|
|
|
80.
|
The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease. [electronic resource] by
- Rogaeva, Ekaterina
- Meng, Yan
- Lee, Joseph H
- Gu, Yongjun
- Kawarai, Toshitaka
- Zou, Fanggeng
- Katayama, Taiichi
- Baldwin, Clinton T
- Cheng, Rong
- Hasegawa, Hiroshi
- Chen, Fusheng
- Shibata, Nobuto
- Lunetta, Kathryn L
- Pardossi-Piquard, Raphaelle
- Bohm, Christopher
- Wakutani, Yosuke
- Cupples, L Adrienne
- Cuenco, Karen T
- Green, Robert C
- Pinessi, Lorenzo
- Rainero, Innocenzo
- Sorbi, Sandro
- Bruni, Amalia
- Duara, Ranjan
- Friedland, Robert P
- Inzelberg, Rivka
- Hampe, Wolfgang
- Bujo, Hideaki
- Song, You-Qiang
- Andersen, Olav M
- Willnow, Thomas E
- Graff-Radford, Neill
- Petersen, Ronald C
- Dickson, Dennis
- Der, Sandy D
- Fraser, Paul E
- Schmitt-Ulms, Gerold
- Younkin, Steven
- Mayeux, Richard
- Farrer, Lindsay A
- St George-Hyslop, Peter
Producer: 20070423
In:
Nature genetics vol. 39
Availability: No items available.
|