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481.
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Pembrolizumab for the treatment of programmed death-ligand 1-positive advanced carcinoid or pancreatic neuroendocrine tumors: Results from the KEYNOTE-028 study. [electronic resource] by
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- Bergsland, Emily
- O'Neil, Bert H
- Santoro, Armando
- Schellens, Jan H M
- Cohen, Roger B
- Doi, Toshihiko
- Ott, Patrick A
- Pishvaian, Michael J
- Puzanov, Igor
- Aung, Kyaw L
- Hsu, Chiun
- Le Tourneau, Christophe
- Hollebecque, Antoine
- Élez, Elena
- Tamura, Kenji
- Gould, Marlena
- Yang, Ping
- Stein, Karen
- Piha-Paul, Sarina A
Producer: 20210513
In:
Cancer vol. 126
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482.
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Dose-response relationship in phase i clinical trials: a European Drug Development Network (EDDN) Collaboration Study. [electronic resource] by
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- Olmos, David
- Gomez-Roca, Carlos
- Cassier, Philippe A
- Morales-Barrera, Rafael
- Del Conte, Gianluca
- Gallerani, Elisa
- Brunetto, Andre T
- Schöffski, Patrick
- Marsoni, Silvia
- Schellens, Jan H M
- Penel, Nicolas
- Voest, Emile
- Evans, Jeffrey
- Plummer, Ruth
- Wilson, Richard H
- Soria, Jean Charles
- Tabernero, Josep
- Verweij, Jaap
- Kaye, Stan B
Producer: 20150709
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 20
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483.
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Semi-physiological model describing the hematological toxicity of the anti-cancer agent indisulam. [electronic resource] by
- van Kesteren, Charlotte
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- Karlsson, Mats O
- Mathôt, Ron A A
- Punt, Cornelis J A
- Armand, Jean-Pierre
- Raymond, Eric
- Huitema, Alwin D R
- Dittrich, Christian
- Dumez, Herlinde
- Roché, Henri H
- Droz, Jean-Pierre
- Ravic, Miroslav
- Yule, S Murray
- Wanders, Jantien
- Beijnen, Jos H
- Fumoleau, Pierre
- Schellens, Jan H M
Producer: 20051007
In:
Investigational new drugs vol. 23
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484.
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Phase I Study of CC-486 Alone and in Combination with Carboplatin or nab-Paclitaxel in Patients with Relapsed or Refractory Solid Tumors. [electronic resource] by
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- Rasco, Drew W
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- Munster, Pamela N
- Schellens, Jan H M
- Isambert, Nicolas
- Le Tourneau, Christophe
- O'Neil, Bert
- Mathijssen, Ron H J
- Lopez-Martin, Jose A
- Edenfield, W Jeff
- Martin, Miguel
- LoRusso, Patricia M
- Bray, Gordon L
- DiMartino, Jorge
- Nguyen, Aaron
- Liu, Kejian
- Laille, Eric
- Bendell, Johanna C
Producer: 20191108
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 24
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485.
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Pembrolizumab After Two or More Lines of Previous Therapy in Patients With Recurrent or Metastatic SCLC: Results From the KEYNOTE-028 and KEYNOTE-158 Studies. [electronic resource] by
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- Piha-Paul, Sarina A
- Lopez-Martin, Jose
- Schellens, Jan H M
- Kao, Steven
- Miller, Wilson H
- Delord, Jean-Pierre
- Gao, Bo
- Planchard, David
- Gottfried, Maya
- Zer, Alona
- Jalal, Shadia I
- Penel, Nicolas
- Mehnert, Janice M
- Matos, Ignacio
- Bennouna, Jaafar
- Kim, Dong-Wan
- Xu, Lei
- Krishnan, Suba
- Norwood, Kevin
- Ott, Patrick A
Producer: 20210106
In:
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer vol. 15
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486.
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Trastuzumab and bevacizumab combined with docetaxel, oxaliplatin and capecitabine as first-line treatment of advanced HER2-positive gastric cancer: a multicenter phase II study. [electronic resource] by
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- Beerepoot, Laurens V
- Boot, Henk
- de Groot, Jan Willem B
- Los, Maartje
- Boers, James E
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- Polee, Marco B
- Beeker, Aart
- Portielje, Johanna E A
- de Jong, Robert S
- Goey, Swan H
- Kuiper, Maria
- Sikorska, Karolina
- Beijnen, Jos H
- Tesselaar, Margot E
- Schellens, Jan H M
- Cats, Annemieke
Producer: 20161107
In:
Investigational new drugs vol. 34
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487.
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Exposure and Tumor Fn14 Expression as Determinants of Pharmacodynamics of the Anti-TWEAK Monoclonal Antibody RG7212 in Patients with Fn14-Positive Solid Tumors. [electronic resource] by
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- Karanikas, Vaios
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- Jonker, Derek J
- Hansen, Aaron R
- Simcox, Mary E
- Schostack, Kathleen J
- Bottino, Dean
- Zhong, Hua
- Roessler, Markus
- Vega-Harring, Suzana M
- Jarutat, Tiantom
- Geho, David
- Wang, Karen
- DeMario, Mark
- Goss, Glenwood D
- Schellens, Jan H M
Producer: 20161103
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 22
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488.
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First-in-Human Phase I Study of Lumretuzumab, a Glycoengineered Humanized Anti-HER3 Monoclonal Antibody, in Patients with Metastatic or Advanced HER3-Positive Solid Tumors. [electronic resource] by
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- Jacob, Wolfgang
- Martinez-Garcia, Maria
- Taus, Alvaro
- Lolkema, Martijn P
- Voest, Emile E
- Langenberg, Marlies H G
- Fleitas Kanonnikoff, Tania
- Cervantes, Andres
- De Jonge, Maja J
- Sleijfer, Stefan
- Soerensen, Morten Mau
- Thomas, Marlene
- Ceppi, Maurizio
- Meneses-Lorente, Georgina
- James, Ian
- Adessi, Celine
- Michielin, Francesca
- Abiraj, Keelara
- Bossenmaier, Birgit
- Schellens, Jan H M
- Weisser, Martin
- Lassen, Ulrik N
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In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 22
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489.
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Population pharmacokinetics and pharmacodynamics of doxorubicin and cyclophosphamide in breast cancer patients: a study by the EORTC-PAMM-NDDG. [electronic resource] by
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- Richel, Dick J
- Dittrich, Christian
- Pavlidis, Nikolas
- Briasoulis, Evangelos
- Vermorken, Jan B
- Strocchi, Elena
- Martoni, Andrea
- Sorio, Roberto
- Sleeboom, Henk P
- Izquierdo, Miguel A
- Jodrell, Duncan I
- Féty, Régine
- de Bruijn, Ernst
- Hempel, Georg
- Karlsson, Mats
- Tranchand, Brigitte
- Schrijvers, Ad H G J
- Twelves, Chris
- Beijnen, Jos H
- Schellens, Jan H M
Producer: 20080403
In:
Clinical pharmacokinetics vol. 46
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490.
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Bevacizumab combined with docetaxel, oxaliplatin, and capecitabine, followed by maintenance with capecitabine and bevacizumab, as first-line treatment of patients with advanced HER2-negative gastric cancer: A multicenter phase 2 study. [electronic resource] by
- Meulendijks, Didier
- de Groot, Jan Willem B
- Los, Maartje
- Boers, James E
- Beerepoot, Laurens V
- Polee, Marco B
- Beeker, Aart
- Portielje, Johanna E A
- Goey, Swan H
- de Jong, Robert S
- Vanhoutvin, Steven A L W
- Kuiper, Maria
- Sikorska, Karolina
- Pluim, Dick
- Beijnen, Jos H
- Schellens, Jan H M
- Grootscholten, Cecile
- Tesselaar, Margot E T
- Cats, Annemieke
Producer: 20170302
In:
Cancer vol. 122
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491.
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None [electronic resource] by
- Middleton, Gary
- Yang, Yiqun
- Campbell, Catarina D
- André, Thierry
- Atreya, Chloe E
- Schellens, Jan H M
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- Bendell, Johanna C
- Hollebecque, Antoine
- McRee, Autumn J
- Siena, Salvatore
- Gordon, Michael S
- Tabernero, Josep
- Yaeger, Rona
- O'Dwyer, Peter J
- De Vos, Filip
- Van Cutsem, Eric
- Millholland, John M
- Brase, Jan C
- Rangwala, Fatima
- Gasal, Eduard
- Corcoran, Ryan B
Producer: 20210903
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 26
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492.
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A phosphotyrosine switch regulates organic cation transporters. [electronic resource] by
- Sprowl, Jason A
- Ong, Su Sien
- Gibson, Alice A
- Hu, Shuiying
- Du, Guoqing
- Lin, Wenwei
- Li, Lie
- Bharill, Shashank
- Ness, Rachel A
- Stecula, Adrian
- Offer, Steven M
- Diasio, Robert B
- Nies, Anne T
- Schwab, Matthias
- Cavaletti, Guido
- Schlatter, Eberhard
- Ciarimboli, Giuliano
- Schellens, Jan H M
- Isacoff, Ehud Y
- Sali, Andrej
- Chen, Taosheng
- Baker, Sharyn D
- Sparreboom, Alex
- Pabla, Navjotsingh
Producer: 20160802
In:
Nature communications vol. 7
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493.
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A phase Ib study of GSK3052230, an FGF ligand trap in combination with pemetrexed and cisplatin in patients with malignant pleural mesothelioma. [electronic resource] by
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- Levchenko, Evgeny
- Dómine, Manuel
- Fennell, Dean A
- Kindler, Hedy L
- Viteri, Santiago
- Gadgeel, Shirish
- López, Pilar Garrido
- Kostorov, Vladimir
- Morgensztern, Daniel
- Orlov, Sergey
- Zauderer, Marjorie G
- Vansteenkiste, Johan F
- Baker-Neblett, Katherine
- Vasquez, James
- Wang, Xiaowei
- Bellovin, David I
- Schellens, Jan H M
- Yan, Li
- Mitrica, Ionel
- DeYoung, M Phillip
- Trigo, José
Producer: 20210303
In:
Investigational new drugs vol. 38
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494.
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A Phase Ib Dose-Escalation Study of Encorafenib and Cetuximab with or without Alpelisib in Metastatic [electronic resource] by
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- Tabernero, Josep
- Elez, Elena
- Bendell, Johanna C
- Spreafico, Anna
- Schuler, Martin
- Yoshino, Takayuki
- Delord, Jean-Pierre
- Yamada, Yasuhide
- Lolkema, Martijn P
- Faris, Jason E
- Eskens, Ferry A L M
- Sharma, Sunil
- Yaeger, Rona
- Lenz, Heinz-Josef
- Wainberg, Zev A
- Avsar, Emin
- Chatterjee, Arkendu
- Jaeger, Savina
- Tan, Eugene
- Maharry, Kati
- Demuth, Tim
- Schellens, Jan H M
Producer: 20180306
In:
Cancer discovery vol. 7
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495.
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None [electronic resource] by
- van Brummelen, Emilie M J
- Huisman, Marc C
- de Wit-van der Veen, Linda J
- Nayak, Tapan K
- Stokkel, Marcel P M
- Mulder, Emma R
- Hoekstra, Otto S
- Vugts, Danielle J
- Van Dongen, Guus A M S
- Verheul, Henk M
- Evers, Stefan
- Tessier, Jean J L
- Saro, Jose
- Schellens, Jan H M
- Menke-van der Houven van Oordt, C Willemien
Publication details: Oncotarget May 2018
In:
Oncotarget vol. 9
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496.
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Clinical relevance of DPYD variants c.1679T>G, c.1236G>A/HapB3, and c.1601G>A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta-analysis of individual patient data. [electronic resource] by
- Meulendijks, Didier
- Henricks, Linda M
- Sonke, Gabe S
- Deenen, Maarten J
- Froehlich, Tanja K
- Amstutz, Ursula
- Largiadèr, Carlo R
- Jennings, Barbara A
- Marinaki, Anthony M
- Sanderson, Jeremy D
- Kleibl, Zdenek
- Kleiblova, Petra
- Schwab, Matthias
- Zanger, Ulrich M
- Palles, Claire
- Tomlinson, Ian
- Gross, Eva
- van Kuilenburg, André B P
- Punt, Cornelis J A
- Koopman, Miriam
- Beijnen, Jos H
- Cats, Annemieke
- Schellens, Jan H M
Producer: 20160418
In:
The Lancet. Oncology vol. 16
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497.
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Combined BRAF, EGFR, and MEK Inhibition in Patients with [electronic resource] by
- Corcoran, Ryan B
- André, Thierry
- Atreya, Chloe E
- Schellens, Jan H M
- Yoshino, Takayuki
- Bendell, Johanna C
- Hollebecque, Antoine
- McRee, Autumn J
- Siena, Salvatore
- Middleton, Gary
- Muro, Kei
- Gordon, Michael S
- Tabernero, Josep
- Yaeger, Rona
- O'Dwyer, Peter J
- Humblet, Yves
- De Vos, Filip
- Jung, A Scott
- Brase, Jan C
- Jaeger, Savina
- Bettinger, Severine
- Mookerjee, Bijoyesh
- Rangwala, Fatima
- Van Cutsem, Eric
Producer: 20190830
In:
Cancer discovery vol. 8
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498.
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Phase 1 study of the pan-HER inhibitor dacomitinib plus the MEK1/2 inhibitor PD-0325901 in patients with KRAS-mutation-positive colorectal, non-small-cell lung and pancreatic cancer. [electronic resource] by
- van Geel, Robin M J M
- van Brummelen, Emilie M J
- Eskens, Ferry A L M
- Huijberts, Sanne C F A
- de Vos, Filip Y F L
- Lolkema, Martijn P J K
- Devriese, Lot A
- Opdam, Frans L
- Marchetti, Serena
- Steeghs, Neeltje
- Monkhorst, Kim
- Thijssen, Bas
- Rosing, Hilde
- Huitema, Alwin D R
- Beijnen, Jos H
- Bernards, René
- Schellens, Jan H M
Producer: 20201230
In:
British journal of cancer vol. 122
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499.
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Evaluation of BGJ398, a Fibroblast Growth Factor Receptor 1-3 Kinase Inhibitor, in Patients With Advanced Solid Tumors Harboring Genetic Alterations in Fibroblast Growth Factor Receptors: Results of a Global Phase I, Dose-Escalation and Dose-Expansion Study. [electronic resource] by
- Nogova, Lucia
- Sequist, Lecia V
- Perez Garcia, Jose Manuel
- Andre, Fabrice
- Delord, Jean-Pierre
- Hidalgo, Manuel
- Schellens, Jan H M
- Cassier, Philippe A
- Camidge, D Ross
- Schuler, Martin
- Vaishampayan, Ulka
- Burris, Howard
- Tian, G Gary
- Campone, Mario
- Wainberg, Zev A
- Lim, Wan-Teck
- LoRusso, Patricia
- Shapiro, Geoffrey I
- Parker, Katie
- Chen, Xueying
- Choudhury, Somesh
- Ringeisen, Francois
- Graus-Porta, Diana
- Porter, Dale
- Isaacs, Randi
- Buettner, Reinhard
- Wolf, Jürgen
Producer: 20170821
In:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology vol. 35
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500.
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Angiotensin II-Receptor Inhibition With Candesartan to Prevent Trastuzumab-Related Cardiotoxic Effects in Patients With Early Breast Cancer: A Randomized Clinical Trial. [electronic resource] by
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- Gietema, Jourik A
- Milojkovic Kerklaan, Bojana
- van Werkhoven, Erik D
- Altena, Renske
- Honkoop, Aafke
- Los, Maartje
- Smit, Willem M
- Nieboer, Peter
- Smorenburg, Carolien H
- Mandigers, Caroline M P W
- van der Wouw, Agnes J
- Kessels, Lonneke
- van der Velden, Annette W G
- Ottevanger, Petronella B
- Smilde, Tineke
- de Boer, Jaap
- van Veldhuisen, Dirk J
- Kema, Ido P
- de Vries, Elisabeth G E
- Schellens, Jan H M
Producer: 20170130
In:
JAMA oncology vol. 2
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