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481.
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Pharmacokinetics and Safety of Olaparib in Patients with Advanced Solid Tumours and Renal Impairment. [electronic resource] by
- Rolfo, Christian
- de Vos-Geelen, Judith
- Isambert, Nicolas
- Molife, L Rhoda
- Schellens, Jan H M
- De Grève, Jacques
- Dirix, Luc
- Grundtvig-Sørensen, Peter
- Jerusalem, Guy
- Leunen, Karin
- Mau-Sørensen, Morten
- Plummer, Ruth
- Learoyd, Maria
- Bannister, Wendy
- Fielding, Anitra
- Ravaud, Alain
Producer: 20200902
In:
Clinical pharmacokinetics vol. 58
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482.
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Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers. [electronic resource] by
- Fong, Peter C
- Boss, David S
- Yap, Timothy A
- Tutt, Andrew
- Wu, Peijun
- Mergui-Roelvink, Marja
- Mortimer, Peter
- Swaisland, Helen
- Lau, Alan
- O'Connor, Mark J
- Ashworth, Alan
- Carmichael, James
- Kaye, Stan B
- Schellens, Jan H M
- de Bono, Johann S
Producer: 20090720
In:
The New England journal of medicine vol. 361
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483.
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Thymidylate synthase maintains the de-differentiated state of triple negative breast cancers. [electronic resource] by
- Siddiqui, Aarif
- Gollavilli, Paradesi Naidu
- Schwab, Annemarie
- Vazakidou, Maria Eleni
- Ersan, Pelin G
- Ramakrishnan, Mallika
- Pluim, Dick
- Coggins, Si'Ana
- Saatci, Ozge
- Annaratone, Laura
- Hm Schellens, Jan
- Kim, Baek
- Asangani, Irfan Ahmed
- Rasheed, Suhail Ahmed Kabeer
- Marchiò, Caterina
- Sahin, Ozgur
- Ceppi, Paolo
Producer: 20200908
In:
Cell death and differentiation vol. 26
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484.
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Detection of breast cancer by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry tissue and serum protein profiling. [electronic resource] by
- Gast, Marie-Christine W
- van Dulken, Eric J
- van Loenen, Thea K G
- Kingma-Vegter, Florine
- Westerga, Johan
- Flohil, Claudie C
- Knol, Jaco C
- Jimenez, Connie R
- van Gils, Carla H
- Wessels, Lodewijk F A
- Schellens, Jan H N
- Beijnen, Jos H
Producer: 20100408
In:
The International journal of biological markers vol. 24
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485.
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Phase I study of docetaxel in combination with the P-glycoprotein inhibitor, zosuquidar, in resistant malignancies. [electronic resource] by
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- Goldstein, Lori J
- de Alwis, Dinesh P
- Rader, Janet S
- Arquette, Matthew A
- Goodner, Sherry A
- Wright, Lisa P
- Fears, Carole L
- Gazak, Robert J
- Andre, Valerie A M
- Burgess, Michael F
- Slapak, Christopher A
- Schellens, Jan H M
Producer: 20050503
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 10
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486.
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Pharmacodynamics and pharmacokinetics of oral topotecan in patients with advanced solid tumours and impaired renal function. [electronic resource] by
- Devriese, Lot A
- Witteveen, Petronella Els O
- Mergui-Roelvink, Marja
- Smith, Deborah A
- Lewis, Lionel D
- Mendelson, David S
- Bang, Yung-Jue
- Chung, Hyun Choel
- Dar, Mohammed M
- Huitema, Alwin D R
- Beijnen, Jos H
- Voest, Emile E
- Schellens, Jan H M
Producer: 20160418
In:
British journal of clinical pharmacology vol. 80
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487.
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Impact of Older Age on the Exposure of Paclitaxel: a Population Pharmacokinetic Study. [electronic resource] by
- Crombag, Marie-Rose B S
- de Vries Schultink, Aurelia H M
- Koolen, Stijn L W
- Wijngaard, Sophie
- Joerger, Markus
- Schellens, Jan H M
- Dorlo, Thomas P C
- van Erp, Nielka P
- Mathijssen, Ron H J
- Beijnen, Jos H
- Huitema, Alwin D R
Producer: 20190128
In:
Pharmaceutical research vol. 36
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488.
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Phase I pharmacokinetic and pharmacodynamic study of the oral protein kinase C beta-inhibitor enzastaurin in combination with gemcitabine and cisplatin in patients with advanced cancer. [electronic resource] by
- Rademaker-Lakhai, Jeany M
- Beerepoot, Laurens V
- Mehra, Niven
- Radema, Sandra A
- van Maanen, Rianne
- Vermaat, Joost S
- Witteveen, Els O
- Visseren-Grul, Carla M
- Musib, Luna
- Enas, Nathan
- van Hal, Gertjan
- Beijnen, Jos H
- Schellens, Jan H M
- Voest, Emile E
Producer: 20071026
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 13
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489.
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Increased incidence of visceral metastases in scottish patients with BRCA1/2-defective ovarian cancer: an extension of the ovarian BRCAness phenotype. [electronic resource] by
- Gourley, Charlie
- Michie, Caroline O
- Roxburgh, Patricia
- Yap, Timothy A
- Harden, Sharon
- Paul, Jim
- Ragupathy, Kalpana
- Todd, Radha
- Petty, Russell
- Reed, Nick
- Hayward, Richard L
- Mitchell, Paul
- Rye, Tzyvia
- Schellens, Jan H M
- Lubinski, Jan
- Carmichael, James
- Kaye, Stan B
- Mackean, Melanie
- Ferguson, Michelle
Producer: 20100908
In:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology vol. 28
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490.
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Validation of serum amyloid α as an independent biomarker for progression-free and overall survival in metastatic renal cell cancer patients. [electronic resource] by
- Vermaat, Joost S
- Gerritse, Frank L
- van der Veldt, Astrid A
- Roessingh, Wijnand M
- Niers, Tatjana M
- Oosting, Sjoukje F
- Sleijfer, Stefan
- Roodhart, Jeanine M
- Beijnen, Jos H
- Schellens, Jan H
- Gietema, Jourik A
- Boven, Epie
- Richel, Dick J
- Haanen, John B
- Voest, Emile E
Producer: 20130208
In:
European urology vol. 62
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491.
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Predictive value of CYP3A and ABCB1 phenotyping probes for the pharmacokinetics of sunitinib: the ClearSun study. [electronic resource] by
- Kloth, Jacqueline S L
- Klümpen, Heinz-Josef
- Yu, Huixin
- Eechoute, Karel
- Samer, Caroline F
- Kam, Boen L R
- Huitema, Alwin D R
- Daali, Youssef
- Zwinderman, Aeilko H
- Balakrishnar, Bavanthi
- Bennink, Roelof J
- Wong, Mark
- Schellens, Jan H M
- Mathijssen, Ron H J
- Gurney, Howard
Producer: 20141208
In:
Clinical pharmacokinetics vol. 53
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492.
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Binimetinib, Encorafenib, and Cetuximab Triplet Therapy for Patients With [electronic resource] by
- Van Cutsem, Eric
- Huijberts, Sanne
- Grothey, Axel
- Yaeger, Rona
- Cuyle, Pieter-Jan
- Elez, Elena
- Fakih, Marwan
- Montagut, Clara
- Peeters, Marc
- Yoshino, Takayuki
- Wasan, Harpreet
- Desai, Jayesh
- Ciardiello, Fortunato
- Gollerkeri, Ashwin
- Christy-Bittel, Janna
- Maharry, Kati
- Sandor, Victor
- Schellens, Jan H M
- Kopetz, Scott
- Tabernero, Josep
Producer: 20200604
In:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology vol. 37
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493.
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Phosphatidylinositol 3-Kinase α-Selective Inhibition With Alpelisib (BYL719) in PIK3CA-Altered Solid Tumors: Results From the First-in-Human Study. [electronic resource] by
- Juric, Dejan
- Rodon, Jordi
- Tabernero, Josep
- Janku, Filip
- Burris, Howard A
- Schellens, Jan H M
- Middleton, Mark R
- Berlin, Jordan
- Schuler, Martin
- Gil-Martin, Marta
- Rugo, Hope S
- Seggewiss-Bernhardt, Ruth
- Huang, Alan
- Bootle, Douglas
- Demanse, David
- Blumenstein, Lars
- Coughlin, Christina
- Quadt, Cornelia
- Baselga, José
Producer: 20190729
In:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology vol. 36
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494.
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Phase I Study Evaluating WEE1 Inhibitor AZD1775 As Monotherapy and in Combination With Gemcitabine, Cisplatin, or Carboplatin in Patients With Advanced Solid Tumors. [electronic resource] by
- Leijen, Suzanne
- van Geel, Robin M J M
- Pavlick, Anna C
- Tibes, Raoul
- Rosen, Lee
- Razak, Albiruni R Abdul
- Lam, Raymond
- Demuth, Tim
- Rose, Shelonitda
- Lee, Mark A
- Freshwater, Tomoko
- Shumway, Stuart
- Liang, Li Wen
- Oza, Amit M
- Schellens, Jan H M
- Shapiro, Geoffrey I
Producer: 20170807
In:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology vol. 34
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495.
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Phase I dose-escalation study of the safety, pharmacokinetics, and pharmacodynamics of the MEK inhibitor RO4987655 (CH4987655) in patients with advanced solid tumors. [electronic resource] by
- Leijen, Suzanne
- Middleton, Mark R
- Tresca, Patricia
- Kraeber-Bodéré, Françoise
- Dieras, Veronique
- Scheulen, Max E
- Gupta, Avinash
- Lopez-Valverde, Vanesa
- Xu, Zhi-Xin
- Rueger, Ruediger
- Tessier, Jean J L
- Shochat, Eliezer
- Blotner, Steve
- Naegelen, Valerie Meresse
- Schellens, Jan H M
- Eberhardt, Wilfried Ernst Erich
Producer: 20130409
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 18
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496.
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Phase I study of lapatinib plus trametinib in patients with KRAS-mutant colorectal, non-small cell lung, and pancreatic cancer. [electronic resource] by
- Huijberts, Sanne C F A
- van Geel, Robin M J M
- van Brummelen, Emilie M J
- Opdam, Frans L
- Marchetti, Serena
- Steeghs, Neeltje
- Pulleman, Saskia
- Thijssen, Bas
- Rosing, Hilde
- Monkhorst, Kim
- Huitema, Alwin D R
- Beijnen, Jos H
- Bernards, René
- Schellens, Jan H M
Producer: 20201117
In:
Cancer chemotherapy and pharmacology vol. 85
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497.
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A Phase I Dose Escalation Study of Once-Weekly Oral Administration of Docetaxel as ModraDoc001 Capsule or ModraDoc006 Tablet in Combination with Ritonavir. [electronic resource] by
- de Weger, Vincent A
- Stuurman, Frederik E
- Koolen, Stijn L W
- Moes, Johannes J
- Hendrikx, Jeroen J M A
- Sawicki, Emilia
- Thijssen, Bas
- Keessen, Marianne
- Rosing, Hilde
- Mergui-Roelvink, Marja
- Huitema, Alwin D R
- Nuijen, Bastiaan
- Beijnen, Jos H
- Schellens, Jan H M
- Marchetti, Serena
Producer: 20200907
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 25
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498.
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First-in-Human Phase I Study of GSK2126458, an Oral Pan-Class I Phosphatidylinositol-3-Kinase Inhibitor, in Patients with Advanced Solid Tumor Malignancies. [electronic resource] by
- Munster, Pamela
- Aggarwal, Rahul
- Hong, David
- Schellens, Jan H M
- van der Noll, Ruud
- Specht, Jennifer
- Witteveen, Petronella O
- Werner, Theresa L
- Dees, E Claire
- Bergsland, Emily
- Agarwal, Neeraj
- Kleha, Joseph F
- Durante, Michael
- Adams, Laurel
- Smith, Deborah A
- Lampkin, Thomas A
- Morris, Shannon R
- Kurzrock, Razelle
Producer: 20161230
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 22
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499.
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Pronounced between-subject and circadian variability in thymidylate synthase and dihydropyrimidine dehydrogenase enzyme activity in human volunteers. [electronic resource] by
- Jacobs, Bart A W
- Deenen, Maarten J
- Pluim, Dick
- van Hasselt, J G Coen
- Krähenbühl, Martin D
- van Geel, Robin M J M
- de Vries, Niels
- Rosing, Hilde
- Meulendijks, Didier
- Burylo, Artur M
- Cats, Annemieke
- Beijnen, Jos H
- Huitema, Alwin D R
- Schellens, Jan H M
Producer: 20171113
In:
British journal of clinical pharmacology vol. 82
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500.
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A first-in-human phase 1 dose escalation study of spartalizumab (PDR001), an anti-PD-1 antibody, in patients with advanced solid tumors. [electronic resource] by
- Naing, Aung
- Gainor, Justin F
- Gelderblom, Hans
- Forde, Patrick M
- Butler, Marcus O
- Lin, Chia-Chi
- Sharma, Sunil
- Ochoa de Olza, Maria
- Varga, Andrea
- Taylor, Matthew
- Schellens, Jan H M
- Wu, Hongqian
- Sun, Haiying
- Silva, Antonio P
- Faris, Jason
- Mataraza, Jennifer
- Cameron, Scott
- Bauer, Todd M
Producer: 20210608
In:
Journal for immunotherapy of cancer vol. 8
Availability: No items available.
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