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Discovery of potent and orally bioavailable heterocycle-based beta3-adrenergic receptor agonists, potential therapeutics for the treatment of obesity. [electronic resource] by
- Lafontaine, Jennifer A
- Day, Robert F
- Dibrino, Joe
- Hadcock, John R
- Hargrove, Diane M
- Linhares, Michael
- Martin, Kelly A
- Maurer, Tristan S
- Nardone, Nancy A
- Tess, David A
- Dasilva-Jardine, Paul
Producer: 20071227
In:
Bioorganic & medicinal chemistry letters vol. 17
Availability: No items available.
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44.
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Asymmetric synthesis of cis-2,5-disubstituted pyrrolidine, the core scaffold of β3-AR agonists. [electronic resource] by
- Xu, Feng
- Chung, John Y L
- Moore, Jeffery C
- Liu, Zhuqing
- Yoshikawa, Naoki
- Hoerrner, R Scott
- Lee, Jaemoon
- Royzen, Maksim
- Cleator, Ed
- Gibson, Andrew G
- Dunn, Robert
- Maloney, Kevin M
- Alam, Mahbub
- Goodyear, Adrian
- Lynch, Joseph
- Yasuda, Nobuyashi
- Devine, Paul N
Producer: 20130724
In:
Organic letters vol. 15
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Discovery of Novel Indazole Derivatives as Orally Available β [electronic resource] by
- Wada, Yasuhiro
- Nakano, Seiji
- Morimoto, Akifumi
- Kasahara, Ken-Ichi
- Hayashi, Takahiko
- Takada, Yoshio
- Suzuki, Hiroko
- Niwa-Sakai, Michiko
- Ohashi, Shigeki
- Mori, Mutsuhiro
- Hirokawa, Takatsugu
- Shuto, Satoshi
Producer: 20170620
In:
Journal of medicinal chemistry vol. 60
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Synthesis of Vibegron Enabled by a Ketoreductase Rationally Designed for High pH Dynamic Kinetic Reduction. [electronic resource] by
- Xu, Feng
- Kosjek, Birgit
- Cabirol, Fabien L
- Chen, Haibin
- Desmond, Richard
- Park, Jeonghan
- Gohel, Anupam P
- Collier, Steven J
- Smith, Derek J
- Liu, Zhuqing
- Janey, Jacob M
- Chung, John Y L
- Alvizo, Oscar
Producer: 20190610
In:
Angewandte Chemie (International ed. in English) vol. 57
Availability: No items available.
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