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41.
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The role of the phospho-CDK2/cyclin A recruitment site in substrate recognition. [electronic resource] by
- Cheng, Kin-Yip
- Noble, Martin E M
- Skamnaki, Vicky
- Brown, Nick R
- Lowe, Ed D
- Kontogiannis, Luke
- Shen, Kui
- Cole, Philip A
- Siligardi, Giuliano
- Johnson, Louise N
Producer: 20061108
In:
The Journal of biological chemistry vol. 281
Availability: No items available.
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42.
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Tuning the Binding Affinity and Selectivity of Perfluoroaryl-Stapled Peptides by Cysteine-Editing. [electronic resource] by
- Verhoork, Sanne J M
- Jennings, Claire E
- Rozatian, Neshat
- Reeks, Judith
- Meng, Jieman
- Corlett, Emily K
- Bunglawala, Fazila
- Noble, Martin E M
- Leach, Andrew G
- Coxon, Christopher R
Producer: 20190122
In:
Chemistry (Weinheim an der Bergstrasse, Germany) vol. 25
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43.
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Searching for cyclin-dependent kinase inhibitors using a new variant of the cope elimination. [electronic resource] by
- Griffin, Roger J
- Henderson, Andrew
- Curtin, Nicola J
- Echalier, Aude
- Endicott, Jane A
- Hardcastle, Ian R
- Newell, David R
- Noble, Martin E M
- Wang, Lan-Zhen
- Golding, Bernard T
Producer: 20070828
In:
Journal of the American Chemical Society vol. 128
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44.
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Analysis of chemical shift changes reveals the binding modes of isoindolinone inhibitors of the MDM2-p53 interaction. [electronic resource] by
- Riedinger, Christiane
- Endicott, Jane A
- Kemp, Stuart J
- Smyth, Lynette A
- Watson, Anna
- Valeur, Eric
- Golding, Bernard T
- Griffin, Roger J
- Hardcastle, Ian R
- Noble, Martin E
- McDonnell, James M
Producer: 20090408
In:
Journal of the American Chemical Society vol. 130
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45.
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Paradoxical activation of the protein kinase-transcription factor ERK5 by ERK5 kinase inhibitors. [electronic resource] by
- Lochhead, Pamela A
- Tucker, Julie A
- Tatum, Natalie J
- Wang, Jinhua
- Oxley, David
- Kidger, Andrew M
- Johnson, Victoria P
- Cassidy, Megan A
- Gray, Nathanael S
- Noble, Martin E M
- Cook, Simon J
Producer: 20200713
In:
Nature communications vol. 11
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46.
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Differential Regulation of G1 CDK Complexes by the Hsp90-Cdc37 Chaperone System. [electronic resource] by
- Hallett, Stephen T
- Pastok, Martyna W
- Morgan, R Marc L
- Wittner, Anita
- Blundell, Katie L I M
- Felletar, Ildiko
- Wedge, Stephen R
- Prodromou, Chrisostomos
- Noble, Martin E M
- Pearl, Laurence H
- Endicott, Jane A
Producer: 20180612
In:
Cell reports vol. 21
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47.
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Molecular basis for the recognition of phosphorylated and phosphoacetylated histone h3 by 14-3-3. [electronic resource] by
- Macdonald, Neil
- Welburn, Julie P I
- Noble, Martin E M
- Nguyen, Anhco
- Yaffe, Michael B
- Clynes, David
- Moggs, Jonathan G
- Orphanides, George
- Thomson, Stuart
- Edmunds, John W
- Clayton, Alison L
- Endicott, Jane A
- Mahadevan, Louis C
Producer: 20060113
In:
Molecular cell vol. 20
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48.
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FragLites-Minimal, Halogenated Fragments Displaying Pharmacophore Doublets. An Efficient Approach to Druggability Assessment and Hit Generation. [electronic resource] by
- Wood, Daniel J
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- Knight, Leanne E
- Al-Khawaldeh, Islam
- Gai, Conghao
- Lin, Shengying
- Martin, Mathew P
- Miller, Duncan C
- Cano, Céline
- Endicott, Jane A
- Hardcastle, Ian R
- Noble, Martin E M
- Waring, Michael J
Producer: 20200914
In:
Journal of medicinal chemistry vol. 62
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49.
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Identification of a novel ligand for the ATAD2 bromodomain with selectivity over BRD4 through a fragment growing approach. [electronic resource] by
- Miller, Duncan C
- Martin, Mathew P
- Adhikari, Santosh
- Brennan, Alfie
- Endicott, Jane A
- Golding, Bernard T
- Hardcastle, Ian R
- Heptinstall, Amy
- Hobson, Stephen
- Jennings, Claire
- Molyneux, Lauren
- Ng, Yvonne
- Wedge, Stephen R
- Noble, Martin E M
- Cano, Celine
Producer: 20190218
In:
Organic & biomolecular chemistry vol. 16
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50.
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Benzene Probes in Molecular Dynamics Simulations Reveal Novel Binding Sites for Ligand Design. [electronic resource] by
- Tan, Yaw Sing
- Reeks, Judith
- Brown, Christopher J
- Thean, Dawn
- Ferrer Gago, Fernando Jose
- Yuen, Tsz Ying
- Goh, Eunice Tze Leng
- Lee, Xue Er Cheryl
- Jennings, Claire E
- Joseph, Thomas L
- Lakshminarayanan, Rajamani
- Lane, David P
- Noble, Martin E M
- Verma, Chandra S
Producer: 20180202
In:
The journal of physical chemistry letters vol. 7
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51.
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8-Substituted O(6)-cyclohexylmethylguanine CDK2 inhibitors: using structure-based inhibitor design to optimize an alternative binding mode. [electronic resource] by
- Carbain, Benoit
- Paterson, David J
- Anscombe, Elizabeth
- Campbell, Allyson J
- Cano, Celine
- Echalier, Aude
- Endicott, Jane A
- Golding, Bernard T
- Haggerty, Karen
- Hardcastle, Ian R
- Jewsbury, Philip J
- Newell, David R
- Noble, Martin E M
- Roche, Celine
- Wang, Lan Z
- Griffin, Roger J
Producer: 20140310
In:
Journal of medicinal chemistry vol. 57
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52.
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Identification and Characterization of an Irreversible Inhibitor of CDK2. [electronic resource] by
- Anscombe, Elizabeth
- Meschini, Elisa
- Mora-Vidal, Regina
- Martin, Mathew P
- Staunton, David
- Geitmann, Matthis
- Danielson, U Helena
- Stanley, Will A
- Wang, Lan Z
- Reuillon, Tristan
- Golding, Bernard T
- Cano, Celine
- Newell, David R
- Noble, Martin E M
- Wedge, Stephen R
- Endicott, Jane A
- Griffin, Roger J
Producer: 20160721
In:
Chemistry & biology vol. 22
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53.
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Structure-based design of 2-arylamino-4-cyclohexylmethoxy-5-nitroso-6-aminopyrimidine inhibitors of cyclin-dependent kinase 2. [electronic resource] by
- Marchetti, Francesco
- Sayle, Kerry L
- Bentley, Johanne
- Clegg, William
- Curtin, Nicola J
- Endicott, Jane A
- Golding, Bernard T
- Griffin, Roger J
- Haggerty, Karen
- Harrington, Ross W
- Mesguiche, Veronique
- Newell, David R
- Noble, Martin E M
- Parsons, Rachel J
- Pratt, David J
- Wang, Lan Z
- Hardcastle, Ian R
Producer: 20070808
In:
Organic & biomolecular chemistry vol. 5
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54.
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MDM2-p53 protein-protein interaction inhibitors: a-ring substituted isoindolinones. [electronic resource] by
- Watson, Anna F
- Liu, Junfeng
- Bennaceur, Karim
- Drummond, Catherine J
- Endicott, Jane A
- Golding, Bernard T
- Griffin, Roger J
- Haggerty, Karen
- Lu, Xiaohong
- McDonnell, James M
- Newell, David R
- Noble, Martin E M
- Revill, Charlotte H
- Riedinger, Christiane
- Xu, Qing
- Zhao, Yan
- Lunec, John
- Hardcastle, Ian R
Producer: 20120416
In:
Bioorganic & medicinal chemistry letters vol. 21
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55.
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Probing the ATP ribose-binding domain of cyclin-dependent kinases 1 and 2 with O(6)-substituted guanine derivatives. [electronic resource] by
- Gibson, Ashleigh E
- Arris, Christine E
- Bentley, Johanne
- Boyle, F Thomas
- Curtin, Nicola J
- Davies, Thomas G
- Endicott, Jane A
- Golding, Bernard T
- Grant, Sharon
- Griffin, Roger J
- Jewsbury, Philip
- Johnson, Louise N
- Mesguiche, Veronique
- Newell, David R
- Noble, Martin E M
- Tucker, Julie A
- Whitfield, Hayley J
Producer: 20020819
In:
Journal of medicinal chemistry vol. 45
Availability: No items available.
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56.
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Structure-based design of 2-arylamino-4-cyclohexylmethyl-5-nitroso-6-aminopyrimidine inhibitors of cyclin-dependent kinases 1 and 2. [electronic resource] by
- Sayle, Kerry L
- Bentley, Johanne
- Boyle, F Thomas
- Calvert, A Hilary
- Cheng, Yuzhu
- Curtin, Nicola J
- Endicott, Jane A
- Golding, Bernard T
- Hardcastle, Ian R
- Jewsbury, Philip
- Mesguiche, Veronique
- Newell, David R
- Noble, Martin E M
- Parsons, Rachel J
- Pratt, David J
- Wang, Lan Z
- Griffin, Roger J
Producer: 20040521
In:
Bioorganic & medicinal chemistry letters vol. 13
Availability: No items available.
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57.
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4-Alkoxy-2,6-diaminopyrimidine derivatives: inhibitors of cyclin dependent kinases 1 and 2. [electronic resource] by
- Mesguiche, Veronique
- Parsons, Rachel J
- Arris, Christine E
- Bentley, Johanne
- Boyle, F Thomas
- Curtin, Nicola J
- Davies, Thomas G
- Endicott, Jane A
- Gibson, Ashleigh E
- Golding, Bernard T
- Griffin, Roger J
- Jewsbury, Philip
- Johnson, Louise N
- Newell, David R
- Noble, Martin E M
- Wang, Lan Z
- Hardcastle, Ian R
Producer: 20030717
In:
Bioorganic & medicinal chemistry letters vol. 13
Availability: No items available.
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58.
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N2-substituted O6-cyclohexylmethylguanine derivatives: potent inhibitors of cyclin-dependent kinases 1 and 2. [electronic resource] by
- Hardcastle, Ian R
- Arris, Christine E
- Bentley, Johanne
- Boyle, F Thomas
- Chen, Yuzhu
- Curtin, Nicola J
- Endicott, Jane A
- Gibson, Ashleigh E
- Golding, Bernard T
- Griffin, Roger J
- Jewsbury, Philip
- Menyerol, Jerome
- Mesguiche, Veronique
- Newell, David R
- Noble, Martin E M
- Pratt, David J
- Wang, Lan-Zhen
- Whitfield, Hayley J
Producer: 20040812
In:
Journal of medicinal chemistry vol. 47
Availability: No items available.
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59.
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Structure-based design of a potent purine-based cyclin-dependent kinase inhibitor. [electronic resource] by
- Davies, Thomas G
- Bentley, Johanne
- Arris, Christine E
- Boyle, F Thomas
- Curtin, Nicola J
- Endicott, Jane A
- Gibson, Ashleigh E
- Golding, Bernard T
- Griffin, Roger J
- Hardcastle, Ian R
- Jewsbury, Philip
- Johnson, Louise N
- Mesguiche, Veronique
- Newell, David R
- Noble, Martin E M
- Tucker, Julie A
- Wang, Lan
- Whitfield, Hayley J
Producer: 20021023
In:
Nature structural biology vol. 9
Availability: No items available.
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60.
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Cyclin-Dependent Kinase (CDK) Inhibitors: Structure-Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substituted 2-Arylaminopurines. [electronic resource] by
- Coxon, Christopher R
- Anscombe, Elizabeth
- Harnor, Suzannah J
- Martin, Mathew P
- Carbain, Benoit
- Golding, Bernard T
- Hardcastle, Ian R
- Harlow, Lisa K
- Korolchuk, Svitlana
- Matheson, Christopher J
- Newell, David R
- Noble, Martin E M
- Sivaprakasam, Mangaleswaran
- Tudhope, Susan J
- Turner, David M
- Wang, Lan Z
- Wedge, Stephen R
- Wong, Christopher
- Griffin, Roger J
- Endicott, Jane A
- Cano, Céline
Producer: 20170807
In:
Journal of medicinal chemistry vol. 60
Availability: No items available.
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