Results
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341521.
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Inhibitors of human immunodeficiency virus type 1 (HIV-1) attachment. 12. Structure-activity relationships associated with 4-fluoro-6-azaindole derivatives leading to the identification of 1-(4-benzoylpiperazin-1-yl)-2-(4-fluoro-7-[1,2,3]triazol-1-yl-1h-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione (BMS-585248). [electronic resource] by
- Regueiro-Ren, Alicia
- Xue, Qiufen M
- Swidorski, Jacob J
- Gong, Yi-Fei
- Mathew, Marina
- Parker, Dawn D
- Yang, Zheng
- Eggers, Betsy
- D'Arienzo, Celia
- Sun, Yongnian
- Malinowski, Jacek
- Gao, Qi
- Wu, Dedong
- Langley, David R
- Colonno, Richard J
- Chien, Caly
- Grasela, Dennis M
- Zheng, Ming
- Lin, Pin-Fang
- Meanwell, Nicholas A
- Kadow, John F
Producer: 20130731
In:
Journal of medicinal chemistry vol. 56
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341522.
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341523.
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Safety and efficacy of an 8-week regimen of grazoprevir plus ruzasvir plus uprifosbuvir compared with grazoprevir plus elbasvir plus uprifosbuvir in participants without cirrhosis infected with hepatitis C virus genotypes 1, 2, or 3 (C-CREST-1 and C-CREST-2, part A): two randomised, phase 2, open-label trials. [electronic resource] by
- Gane, Edward J
- Pianko, Stephen
- Roberts, Stuart K
- Thompson, Alexander J
- Zeuzem, Stefan
- Zuckerman, Eli
- Ben-Ari, Ziv
- Foster, Graham R
- Agarwal, Kosh
- Laursen, Alex L
- Gerstoft, Jan
- Gao, Wei
- Huang, Hsueh-Cheng
- Fitzgerald, Brian
- Fernsler, Doreen
- Li, Jerry J
- Grandhi, Anjana
- Liu, Hong
- Su, Feng-Hsiu
- Wan, Shuyan
- Zeng, Zhen
- Chen, Huei-Ling
- Dutko, Frank J
- Nguyen, Bach-Yen T
- Wahl, Janice
- Robertson, Michael N
- Barr, Eliav
- Yeh, Wendy W
- Plank, Rebeca M
- Butterton, Joan R
- Esteban, Rafael
Producer: 20180723
In:
The lancet. Gastroenterology & hepatology vol. 2
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341524.
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341525.
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341526.
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Safety and immunogenicity of a live recombinant canarypox virus expressing HIV type 1 gp120 MN MN tm/gag/protease LAI (ALVAC-HIV, vCP205) followed by a p24E-V3 MN synthetic peptide (CLTB-36) administered in healthy volunteers at low risk for HIV infection. AGIS Group and L'Agence Nationale de Recherches sur Le Sida. [electronic resource] by
- Salmon-Céron, D
- Excler, J L
- Finkielsztejn, L
- Autran, B
- Gluckman, J C
- Sicard, D
- Matthews, T J
- Meignier, B
- Valentin, C
- El Habib, R
- Blondeau, C
- Raux, M
- Moog, C
- Tartaglia, J
- Chong, P
- Klein, M
- Milcamps, B
- Heshmati, F
- Plotkin, S
Producer: 19990806
In:
AIDS research and human retroviruses vol. 15
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341527.
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341528.
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341529.
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341530.
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341531.
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341532.
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Efficacy and safety of 12 weeks versus 18 weeks of treatment with grazoprevir (MK-5172) and elbasvir (MK-8742) with or without ribavirin for hepatitis C virus genotype 1 infection in previously untreated patients with cirrhosis and patients with previous null response with or without cirrhosis (C-WORTHY): a randomised, open-label phase 2 trial. [electronic resource] by
- Lawitz, Eric
- Gane, Edward
- Pearlman, Brian
- Tam, Edward
- Ghesquiere, Wayne
- Guyader, Dominique
- Alric, Laurent
- Bronowicki, Jean-Pierre
- Lester, Laura
- Sievert, William
- Ghalib, Reem
- Balart, Luis
- Sund, Fredrik
- Lagging, Martin
- Dutko, Frank
- Shaughnessy, Melissa
- Hwang, Peggy
- Howe, Anita Y M
- Wahl, Janice
- Robertson, Michael
- Barr, Eliav
- Haber, Barbara
Producer: 20150408
In:
Lancet (London, England) vol. 385
Availability: No items available.
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341533.
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Inhibitors of human immunodeficiency virus type 1 (HIV-1) attachment. 5. An evolution from indole to azaindoles leading to the discovery of 1-(4-benzoylpiperazin-1-yl)-2-(4,7-dimethoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione (BMS-488043), a drug candidate that demonstrates antiviral activity in HIV-1-infected subjects. [electronic resource] by
- Wang, Tao
- Yin, Zhiwei
- Zhang, Zhongxing
- Bender, John A
- Yang, Zhong
- Johnson, Graham
- Yang, Zheng
- Zadjura, Lisa M
- D'Arienzo, Celia J
- DiGiugno Parker, Dawn
- Gesenberg, Christophe
- Yamanaka, Gregory A
- Gong, Yi-Fei
- Ho, Hsu-Tso
- Fang, Hua
- Zhou, Nannan
- McAuliffe, Brian V
- Eggers, Betsy J
- Fan, Li
- Nowicka-Sans, Beata
- Dicker, Ira B
- Gao, Qi
- Colonno, Richard J
- Lin, Pin-Fang
- Meanwell, Nicholas A
- Kadow, John F
Producer: 20091231
In:
Journal of medicinal chemistry vol. 52
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341534.
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341535.
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341536.
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341537.
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341538.
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341539.
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341540.
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Discovery of (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]- 3-[2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (SCH 503034), a selective, potent, orally bioavailable hepatitis C virus NS3 protease inhibitor: a potential therapeutic agent for the treatment of hepatitis C infection. [electronic resource] by
- Venkatraman, Srikanth
- Bogen, Stéphane L
- Arasappan, Ashok
- Bennett, Frank
- Chen, Kevin
- Jao, Edwin
- Liu, Yi-Tsung
- Lovey, Raymond
- Hendrata, Siska
- Huang, Yuhua
- Pan, Weidong
- Parekh, Tejal
- Pinto, Patrick
- Popov, Veljko
- Pike, Russel
- Ruan, Sumei
- Santhanam, Bama
- Vibulbhan, Bancha
- Wu, Wanli
- Yang, Weiying
- Kong, Jianshe
- Liang, Xiang
- Wong, Jesse
- Liu, Rong
- Butkiewicz, Nancy
- Chase, Robert
- Hart, Andrea
- Agrawal, Sony
- Ingravallo, Paul
- Pichardo, John
- Kong, Rong
- Baroudy, Bahige
- Malcolm, Bruce
- Guo, Zhuyan
- Prongay, Andrew
- Madison, Vincent
- Broske, Lisa
- Cui, Xiaoming
- Cheng, Kuo-Chi
- Hsieh, Yunsheng
- Brisson, Jean-Marc
- Prelusky, Danial
- Korfmacher, Walter
- White, Ronald
- Bogdanowich-Knipp, Susan
- Pavlovsky, Anastasia
- Bradley, Prudence
- Saksena, Anil K
- Ganguly, Ashit
- Piwinski, John
- Girijavallabhan, Viyyoor
- Njoroge, F George
Producer: 20061027
In:
Journal of medicinal chemistry vol. 49
Availability: No items available.
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