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Creating novel activated factor XI inhibitors through fragment based lead generation and structure aided drug design. [electronic resource] by
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- Akkaya, Sibel
- Beisel, Hans-Georg
- Eriksson, Per-Olof
- Erixon, Karl
- Gustafsson, David
- Jurva, Ulrik
- Kang, Daiwu
- Karis, David
- Knecht, Wolfgang
- Nerme, Viveca
- Nilsson, Ingemar
- Olsson, Thomas
- Redzic, Alma
- Roth, Robert
- Sandmark, Jenny
- Tigerström, Anna
- Öster, Linda
Producer: 20151007
In:
PloS one vol. 10
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Potent, Orally Bioavailable, and Efficacious Macrocyclic Inhibitors of Factor XIa. Discovery of Pyridine-Based Macrocycles Possessing Phenylazole Carboxamide P1 Groups. [electronic resource] by
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- Fang, Tianan
- Osuna, Honey
- Yang, Wu
- Wang, Yufeng
- Lai, Amy
- Clark, Charles G
- Sun, Jung-Hui
- Rampulla, Richard
- Mathur, Arvind
- Kaspady, Mahammed
- Neithnadka, Premsai Rai
- Li, Yi-Xin Cindy
- Rossi, Karen A
- Myers, Joseph E
- Sheriff, Steven
- Lou, Zhen
- Harper, Timothy W
- Huang, Christine
- Zheng, Joanna J
- Bozarth, Jeffrey M
- Wu, Yiming
- Wong, Pancras C
- Crain, Earl J
- Seiffert, Dietmar A
- Luettgen, Joseph M
- Lam, Patrick Y S
- Wexler, Ruth R
- Ewing, William R
Producer: 20200727
In:
Journal of medicinal chemistry vol. 63
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Ir-CPI, a coagulation contact phase inhibitor from the tick Ixodes ricinus, inhibits thrombus formation without impairing hemostasis. [electronic resource] by
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- Rath, Géraldine
- Blasioli, Virginie
- Cauchie, Philippe
- Robert, Séverine
- Beaufays, Jérôme
- Frère, Jean-Marie
- Feron, Olivier
- Dogné, Jean-Michel
- Dessy, Chantal
- Vanhamme, Luc
- Godfroid, Edmond
Producer: 20091116
In:
The Journal of experimental medicine vol. 206
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A mechanism for hereditary angioedema with normal C1 inhibitor: an inhibitory regulatory role for the factor XII heavy chain. [electronic resource] by
- Ivanov, Ivan
- Matafonov, Anton
- Sun, Mao-Fu
- Mohammed, Bassem M
- Cheng, Qiufang
- Dickeson, S Kent
- Kundu, Suman
- Verhamme, Ingrid M
- Gruber, Andras
- McCrae, Keith
- Gailani, David
Producer: 20191112
In:
Blood vol. 133
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