Results
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299621.
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299622.
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299623.
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299624.
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299625.
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299626.
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Design and synthesis of highly potent benzodiazepine gamma-secretase inhibitors: preparation of (2S,3R)-3-(3,4-difluorophenyl)-2-(4-fluorophenyl)-4- hydroxy-N-((3S)-1-methyl-2-oxo-5- phenyl-2,3-dihydro-1H-benzo[e][1,4]-diazepin-3-yl)butyramide by use of an asymmetric Ireland-Claisen rearrangement. [electronic resource] by
- Churcher, Ian
- Williams, Susie
- Kerrad, Sonia
- Harrison, Timothy
- Castro, José L
- Shearman, Mark S
- Lewis, Huw D
- Clarke, Earl E
- Wrigley, Jonathan D J
- Beher, Dirk
- Tang, Yui S
- Liu, Wensheng
Producer: 20030711
In:
Journal of medicinal chemistry vol. 46
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299627.
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Short and stereoselective total synthesis of furano lignans (+/-)-dihydrosesamin, (+/-)-lariciresinol dimethyl ether, (+/-)-acuminatin methyl ether, (+/-)-sanshodiol methyl ether, (+/-)-lariciresinol, (+/-)-acuminatin, and (+/-)-lariciresinol monomethyl ether and furofuran lignans (+/-)-sesamin, (+/-)-eudesmin, (+/-)-piperitol methyl ether, (+/-)-pinoresinol, (+/-)-piperitol, and (+/-)-pinoresinol monomethyl ether by radical cyclization of epoxides using a transition-metal radical source. [electronic resource] by Producer: 20021209
In:
The Journal of organic chemistry vol. 67
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299628.
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299629.
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299630.
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299631.
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Synthesis, structure-activity relationships, and in vivo efficacy of the novel potent and selective anaplastic lymphoma kinase (ALK) inhibitor 5-chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine (LDK378) currently in phase 1 and phase 2 clinical trials. [electronic resource] by
- Marsilje, Thomas H
- Pei, Wei
- Chen, Bei
- Lu, Wenshuo
- Uno, Tetsuo
- Jin, Yunho
- Jiang, Tao
- Kim, Sungjoon
- Li, Nanxin
- Warmuth, Markus
- Sarkisova, Yelena
- Sun, Frank
- Steffy, Auzon
- Pferdekamper, AnneMarie C
- Li, Allen G
- Joseph, Sean B
- Kim, Young
- Liu, Bo
- Tuntland, Tove
- Cui, Xiaoming
- Gray, Nathanael S
- Steensma, Ruo
- Wan, Yongqin
- Jiang, Jiqing
- Chopiuk, Greg
- Li, Jie
- Gordon, W Perry
- Richmond, Wendy
- Johnson, Kevin
- Chang, Jonathan
- Groessl, Todd
- He, You-Qun
- Phimister, Andrew
- Aycinena, Alex
- Lee, Christian C
- Bursulaya, Badry
- Karanewsky, Donald S
- Seidel, H Martin
- Harris, Jennifer L
- Michellys, Pierre-Yves
Producer: 20140310
In:
Journal of medicinal chemistry vol. 56
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299632.
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299633.
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299634.
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299635.
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Synthesis and characterization of the diruthenium(III) complexes Ru2(F4Oap)2(F5ap)2 and Ru2(F4Oap)(F4NCNap)(F5ap)2 where F4Oap is the 2-(3,4,5,6-tetrafluoro-2-oxoanilino)pyridinate anion, F4NCNap is the 2-(3,4,5,6-tetrafluoro-2-cyanamidoanilino)pyridinate anion, and F5ap is the 2-(2,3,4,5,6-pentafluoroanilino)pyridinate anion. [electronic resource] by Producer: 20010222
In:
Inorganic chemistry vol. 40
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299636.
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299637.
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Design and synthesis of imidazoline derivatives active on glucose homeostasis in a rat model of type II diabetes. 2. Syntheses and biological activities of 1,4-dialkyl-, 1,4-dibenzyl, and 1-benzyl-4-alkyl-2-(4',5'-dihydro-1'H-imidazol-2'-yl)piperazines and isosteric analogues of imidazoline. [electronic resource] by
- Le Bihan, G
- Rondu, F
- Pelé-Tounian, A
- Wang, X
- Lidy, S
- Touboul, E
- Lamouri, A
- Dive, G
- Huet, J
- Pfeiffer, B
- Renard, P
- Guardiola-Lemaître, B
- Manéchez, D
- Pénicaud, L
- Ktorza, A
- Godfroid, J J
Producer: 19990603
In:
Journal of medicinal chemistry vol. 42
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299638.
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Synthesis of the water soluble ligands dmPTA and dmoPTA and the complex [RuClCp(HdmoPTA)(PPh(3))](OSO(2)CF(3)) (dmPTA = N,N'-Dimethyl-1,3,5-triaza-7-phosphaadamantane, dmoPTA = 3,7-Dimethyl-1,3,7-triaza-5-phosphabicyclo[3.3.1]nonane, HdmoPTA = 3,7-H-3,7-Dimethyl-1,3,7-triaza-5-phosphabicyclo[3.3.1]nonane). [electronic resource] by Producer: 20070820
In:
Inorganic chemistry vol. 46
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299639.
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Design and synthesis of novel derivatives of the muscarinic agonist tetra(ethylene glycol)(3-methoxy-1,2,5-thiadiazol-4-yl) [3-(1-methyl-1,2,5,6-tetrahydropyrid-3-yl)-1,2,5-thiadiazol-4-yl] ether (CDD-0304): effects of structural modifications on the binding and activity at muscarinic receptor subtypes and chimeras. [electronic resource] by
- Tejada, Frederick R
- Nagy, Peter I
- Xu, Min
- Wu, Cindy
- Katz, Tricia
- Dorsey, Jason
- Rieman, Melissa
- Lawlor, Elizabeth
- Warrier, Manya
- Messer, William S
Producer: 20070223
In:
Journal of medicinal chemistry vol. 49
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299640.
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Synthesis of a uranium(VI)-carbene: reductive formation of uranyl(V)-methanides, oxidative preparation of a [R2C═U═O]2+ analogue of the [O═U═O]2+ uranyl ion (R = Ph2PNSiMe3), and comparison of the nature of U(IV)═C, U(V)═C, and U(VI)═C double bonds. [electronic resource] by
- Mills, David P
- Cooper, Oliver J
- Tuna, Floriana
- McInnes, Eric J L
- Davies, E Stephen
- McMaster, Jonathan
- Moro, Fabrizio
- Lewis, William
- Blake, Alexander J
- Liddle, Stephen T
Producer: 20121015
In:
Journal of the American Chemical Society vol. 134
Availability: No items available.
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