Results
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2921.
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2922.
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2923.
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2924.
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Discovery of a novel class of exquisitely selective mesenchymal-epithelial transition factor (c-MET) protein kinase inhibitors and identification of the clinical candidate 2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol (PF-04217903) for the treatment of cancer. [electronic resource] by
- Cui, J Jean
- McTigue, Michele
- Nambu, Mitchell
- Tran-Dubé, Michelle
- Pairish, Mason
- Shen, Hong
- Jia, Lei
- Cheng, Hengmiao
- Hoffman, Jacqui
- Le, Phuong
- Jalaie, Mehran
- Goetz, Gilles H
- Ryan, Kevin
- Grodsky, Neil
- Deng, Ya-li
- Parker, Max
- Timofeevski, Sergei
- Murray, Brion W
- Yamazaki, Shinji
- Aguirre, Shirley
- Li, Qiuhua
- Zou, Helen
- Christensen, James
Producer: 20121204
In:
Journal of medicinal chemistry vol. 55
Availability: No items available.
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2925.
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2926.
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Discovery of 1-[3-(1-methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl]-N-(pyridin-2-ylmethyl)methanesulfonamide (MK-8033): A Specific c-Met/Ron dual kinase inhibitor with preferential affinity for the activated state of c-Met. [electronic resource] by
- Northrup, Alan B
- Katcher, Matthew H
- Altman, Michael D
- Chenard, Melissa
- Daniels, Matthew H
- Deshmukh, Sujal V
- Falcone, Danielle
- Guerin, David J
- Hatch, Harold
- Li, Chaomin
- Lu, Wei
- Lutterbach, Bart
- Allison, Timothy J
- Patel, Sangita B
- Reilly, John F
- Reutershan, Michael
- Rickert, Keith W
- Rosenstein, Craig
- Soisson, Stephen M
- Szewczak, Alexander A
- Walker, Deborah
- Wilson, Kevin
- Young, Jonathan R
- Pan, Bo-Sheng
- Dinsmore, Christopher J
Producer: 20130523
In:
Journal of medicinal chemistry vol. 56
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2927.
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2928.
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2929.
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2930.
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2931.
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The novel c-Met inhibitor cabozantinib overcomes gemcitabine resistance and stem cell signaling in pancreatic cancer. [electronic resource] by
- Hage, C
- Rausch, V
- Giese, N
- Giese, T
- Schönsiegel, F
- Labsch, S
- Nwaeburu, C
- Mattern, J
- Gladkich, J
- Herr, I
Producer: 20131023
In:
Cell death & disease vol. 4
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2932.
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The miR-199a/Brm/EGR1 axis is a determinant of anchorage-independent growth in epithelial tumor cell lines. [electronic resource] by
- Kobayashi, Kazuyoshi
- Sakurai, Kouhei
- Hiramatsu, Hiroaki
- Inada, Ken-ichi
- Shiogama, Kazuya
- Nakamura, Shinya
- Suemasa, Fumiko
- Kobayashi, Kyosuke
- Imoto, Seiya
- Haraguchi, Takeshi
- Ito, Hiroaki
- Ishizaka, Aya
- Tsutsumi, Yutaka
- Iba, Hideo
Producer: 20160202
In:
Scientific reports vol. 5
Availability: No items available.
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2933.
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Comprehensive gene and microRNA expression profiling reveals miR-206 inhibits MET in lung cancer metastasis. [electronic resource] by
- Chen, Qing-yong
- Jiao, De-min
- Yan, Li
- Wu, Yu-quan
- Hu, Hui-zhen
- Song, Jia
- Yan, Jie
- Wu, Li-jun
- Xu, Li-qun
- Shi, Jian-guo
Producer: 20160411
In:
Molecular bioSystems vol. 11
Availability: No items available.
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2934.
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2935.
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Quercetin inhibits HGF/c-Met signaling and HGF-stimulated melanoma cell migration and invasion. [electronic resource] by
- Cao, Hui-Hui
- Cheng, Chi-Yan
- Su, Tao
- Fu, Xiu-Qiong
- Guo, Hui
- Li, Ting
- Tse, Anfernee Kai-Wing
- Kwan, Hiu-Yee
- Yu, Hua
- Yu, Zhi-Ling
Producer: 20160204
In:
Molecular cancer vol. 14
Availability: No items available.
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2936.
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Activation of MET via diverse exon 14 splicing alterations occurs in multiple tumor types and confers clinical sensitivity to MET inhibitors. [electronic resource] by
- Frampton, Garrett M
- Ali, Siraj M
- Rosenzweig, Mark
- Chmielecki, Juliann
- Lu, Xinyuan
- Bauer, Todd M
- Akimov, Mikhail
- Bufill, Jose A
- Lee, Carrie
- Jentz, David
- Hoover, Rick
- Ou, Sai-Hong Ignatius
- Salgia, Ravi
- Brennan, Tim
- Chalmers, Zachary R
- Jaeger, Savina
- Huang, Alan
- Elvin, Julia A
- Erlich, Rachel
- Fichtenholtz, Alex
- Gowen, Kyle A
- Greenbowe, Joel
- Johnson, Adrienne
- Khaira, Depinder
- McMahon, Caitlin
- Sanford, Eric M
- Roels, Steven
- White, Jared
- Greshock, Joel
- Schlegel, Robert
- Lipson, Doron
- Yelensky, Roman
- Morosini, Deborah
- Ross, Jeffrey S
- Collisson, Eric
- Peters, Malte
- Stephens, Philip J
- Miller, Vincent A
Producer: 20160505
In:
Cancer discovery vol. 5
Availability: No items available.
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2937.
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2938.
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2939.
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2940.
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