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2301.
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2302.
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Discovery of a potent, selective, and orally bioavailable pyridinyl-pyrimidine phthalazine aurora kinase inhibitor. [electronic resource] by
- Cee, Victor J
- Schenkel, Laurie B
- Hodous, Brian L
- Deak, Holly L
- Nguyen, Hanh N
- Olivieri, Philip R
- Romero, Karina
- Bak, Annette
- Be, Xuhai
- Bellon, Steve
- Bush, Tammy L
- Cheng, Alan C
- Chung, Grace
- Coats, Steve
- Eden, Patrick M
- Hanestad, Kelly
- Gallant, Paul L
- Gu, Yan
- Huang, Xin
- Kendall, Richard L
- Lin, Min-Hwa Jasmine
- Morrison, Michael J
- Patel, Vinod F
- Radinsky, Robert
- Rose, Paul E
- Ross, Sandra
- Sun, Ji-Rong
- Tang, Jin
- Zhao, Huilin
- Payton, Marc
- Geuns-Meyer, Stephanie D
Producer: 20100930
In:
Journal of medicinal chemistry vol. 53
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2303.
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2304.
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Phase II, open-label study of PTK787/ZK222584 for the treatment of metastatic gastrointestinal stromal tumors resistant to imatinib mesylate. [electronic resource] by
- Joensuu, H
- De Braud, F
- Coco, P
- De Pas, T
- Putzu, C
- Spreafico, C
- Bono, P
- Bosselli, S
- Jalava, T
- Laurent, D
- Casali, P G
Producer: 20080214
In:
Annals of oncology : official journal of the European Society for Medical Oncology vol. 19
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2305.
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2306.
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A BRCA1 deficient-like signature is enriched in breast cancer brain metastases and predicts DNA damage-induced poly (ADP-ribose) polymerase inhibitor sensitivity. [electronic resource] by
- McMullin, Ryan P
- Wittner, Ben S
- Yang, Chuanwei
- Denton-Schneider, Benjamin R
- Hicks, Daniel
- Singavarapu, Raj
- Moulis, Sharon
- Lee, Jeongeun
- Akbari, Mohammad R
- Narod, Steven A
- Aldape, Kenneth D
- Steeg, Patricia S
- Ramaswamy, Sridhar
- Sgroi, Dennis C
Producer: 20150206
In:
Breast cancer research : BCR vol. 16
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2307.
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Transient antiangiogenic treatment improves delivery of cytotoxic compounds and therapeutic outcome in lung cancer. [electronic resource] by
- Chatterjee, Sampurna
- Wieczorek, Caroline
- Schöttle, Jakob
- Siobal, Maike
- Hinze, Yvonne
- Franz, Thomas
- Florin, Alexandra
- Adamczak, Joanna
- Heukamp, Lukas C
- Neumaier, Bernd
- Ullrich, Roland T
Producer: 20140807
In:
Cancer research vol. 74
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2308.
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Discovery and Characterization of (8S,9R)-5-Fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-2,7,8,9-tetrahydro-3H-pyrido[4,3,2-de]phthalazin-3-one (BMN 673, Talazoparib), a Novel, Highly Potent, and Orally Efficacious Poly(ADP-ribose) Polymerase-1/2 Inhibitor, as an Anticancer Agent. [electronic resource] by Producer: 20160518
In:
Journal of medicinal chemistry vol. 59
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2309.
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2310.
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Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance. [electronic resource] by
- Pettitt, Stephen J
- Krastev, Dragomir B
- Brandsma, Inger
- Dréan, Amy
- Song, Feifei
- Aleksandrov, Radoslav
- Harrell, Maria I
- Menon, Malini
- Brough, Rachel
- Campbell, James
- Frankum, Jessica
- Ranes, Michael
- Pemberton, Helen N
- Rafiq, Rumana
- Fenwick, Kerry
- Swain, Amanda
- Guettler, Sebastian
- Lee, Jung-Min
- Swisher, Elizabeth M
- Stoynov, Stoyno
- Yusa, Kosuke
- Ashworth, Alan
- Lord, Christopher J
Producer: 20181211
In:
Nature communications vol. 9
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2311.
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2312.
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Effects of PTK787/ZK 222584, a specific inhibitor of vascular endothelial growth factor receptor tyrosine kinases, on primary tumor, metastasis, vessel density, and blood flow in a murine renal cell carcinoma model. [electronic resource] by
- Drevs, J
- Hofmann, I
- Hugenschmidt, H
- Wittig, C
- Madjar, H
- Müller, M
- Wood, J
- Martiny-Baron, G
- Unger, C
- Marmé, D
Producer: 20000928
In:
Cancer research vol. 60
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2313.
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The vascular endothelial growth factor receptor tyrosine kinase inhibitor PTK787/ZK222584 inhibits growth and migration of multiple myeloma cells in the bone marrow microenvironment. [electronic resource] by
- Lin, Boris
- Podar, Klaus
- Gupta, Deepak
- Tai, Yu-Tzu
- Li, Sigui
- Weller, Edie
- Hideshima, Teru
- Lentzsch, Suzanne
- Davies, Faith
- Li, Cheng
- Weisberg, Ellen
- Schlossman, Robert L
- Richardson, Paul G
- Griffin, James D
- Wood, Jeanette
- Munshi, Nikhil C
- Anderson, Kenneth C
Producer: 20021003
In:
Cancer research vol. 62
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2319.
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2320.
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Targeting PARP1 in XRCC1-Deficient Sporadic Invasive Breast Cancer or Preinvasive Ductal Carcinoma [electronic resource] by
- Ali, Reem
- Al-Kawaz, Abdulbaqi
- Toss, Michael S
- Green, Andrew R
- Miligy, Islam M
- Mesquita, Katia A
- Seedhouse, Claire
- Mirza, Sameer
- Band, Vimla
- Rakha, Emad A
- Madhusudan, Srinivasan
Producer: 20191007
In:
Cancer research vol. 78
Availability: No items available.
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