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Reduced folate carrier and folylpolyglutamate synthetase, but not thymidylate synthase predict survival in pemetrexed-treated patients suffering from malignant pleural mesothelioma. [electronic resource] by
- Mairinger, Fabian
- Vollbrecht, Claudia
- Halbwedl, Iris
- Hatz, Martina
- Stacher, Elvira
- Gülly, Christian
- Quehenberger, Franz
- Stephan-Falkenau, Susann
- Kollmeier, Jens
- Roth, Andreas
- Mairinger, Thomas
- Popper, Helmut
Producer: 20131224
In:
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer vol. 8
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Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis. [electronic resource] by
- Golani, Lalit K
- Wallace-Povirk, Adrianne
- Deis, Siobhan M
- Wong, Jennifer
- Ke, Jiyuan
- Gu, Xin
- Raghavan, Sudhir
- Wilson, Mike R
- Li, Xinxin
- Polin, Lisa
- de Waal, Parker W
- White, Kathryn
- Kushner, Juiwanna
- O'Connor, Carrie
- Hou, Zhanjun
- Xu, H Eric
- Melcher, Karsten
- Dann, Charles E
- Matherly, Larry H
- Gangjee, Aleem
Producer: 20170710
In:
Journal of medicinal chemistry vol. 59
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Biochemical and biological studies on 2-desamino-2-methylaminopterin, an antifolate the polyglutamates of which are more potent than the monoglutamate against three key enzymes of folate metabolism. [electronic resource] by
- Rosowsky, A
- Galivan, J
- Beardsley, G P
- Bader, H
- O'Connor, B M
- Russello, O
- Moroson, B A
- DeYarman, M T
- Kerwar, S S
- Freisheim, J H
Producer: 19920508
In:
Cancer research vol. 52
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Methotrexate enhances the antianabolic and antiproliferative effects of 5-aminoimidazole-4-carboxamide riboside. [electronic resource] by
- Beckers, Annelies
- Organe, Sophie
- Timmermans, Leen
- Vanderhoydonc, Frank
- Deboel, Ludo
- Derua, Rita
- Waelkens, Etienne
- Brusselmans, Koen
- Verhoeven, Guido
- Swinnen, Johannes V
Producer: 20061207
In:
Molecular cancer therapeutics vol. 5
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