Results
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221.
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Bitopic Binding Mode of an M [electronic resource] by
- Bradley, Sophie J
- Molloy, Colin
- Bundgaard, Christoffer
- Mogg, Adrian J
- Thompson, Karen J
- Dwomoh, Louis
- Sanger, Helen E
- Crabtree, Michael D
- Brooke, Simon M
- Sexton, Patrick M
- Felder, Christian C
- Christopoulos, Arthur
- Broad, Lisa M
- Tobin, Andrew B
- Langmead, Christopher J
Producer: 20190201
In:
Molecular pharmacology vol. 93
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222.
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Molecular Basis for Hormone Recognition and Activation of Corticotropin-Releasing Factor Receptors. [electronic resource] by
- Ma, Shanshan
- Shen, Qingya
- Zhao, Li-Hua
- Mao, Chunyou
- Zhou, X Edward
- Shen, Dan-Dan
- de Waal, Parker W
- Bi, Peng
- Li, Chuntao
- Jiang, Yi
- Wang, Ming-Wei
- Sexton, Patrick M
- Wootten, Denise
- Melcher, Karsten
- Zhang, Yan
- Xu, H Eric
Producer: 20200427
In:
Molecular cell vol. 77
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223.
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Phase-plate cryo-EM structure of a class B GPCR-G-protein complex. [electronic resource] by
- Liang, Yi-Lynn
- Khoshouei, Maryam
- Radjainia, Mazdak
- Zhang, Yan
- Glukhova, Alisa
- Tarrasch, Jeffrey
- Thal, David M
- Furness, Sebastian G B
- Christopoulos, George
- Coudrat, Thomas
- Danev, Radostin
- Baumeister, Wolfgang
- Miller, Laurence J
- Christopoulos, Arthur
- Kobilka, Brian K
- Wootten, Denise
- Skiniotis, Georgios
- Sexton, Patrick M
Producer: 20171013
In:
Nature vol. 546
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224.
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Activation and allosteric modulation of a muscarinic acetylcholine receptor. [electronic resource] by
- Kruse, Andrew C
- Ring, Aaron M
- Manglik, Aashish
- Hu, Jianxin
- Hu, Kelly
- Eitel, Katrin
- Hübner, Harald
- Pardon, Els
- Valant, Celine
- Sexton, Patrick M
- Christopoulos, Arthur
- Felder, Christian C
- Gmeiner, Peter
- Steyaert, Jan
- Weis, William I
- Garcia, K Christopher
- Wess, Jürgen
- Kobilka, Brian K
Producer: 20131227
In:
Nature vol. 504
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225.
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International Union of Basic and Clinical Pharmacology. XC. multisite pharmacology: recommendations for the nomenclature of receptor allosterism and allosteric ligands. [electronic resource] by
- Christopoulos, Arthur
- Changeux, Jean-Pierre
- Catterall, William A
- Fabbro, Doriano
- Burris, Thomas P
- Cidlowski, John A
- Olsen, Richard W
- Peters, John A
- Neubig, Richard R
- Pin, Jean-Philippe
- Sexton, Patrick M
- Kenakin, Terry P
- Ehlert, Frederick J
- Spedding, Michael
- Langmead, Christopher J
Producer: 20150330
In:
Pharmacological reviews vol. 66
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226.
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Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor-Gs complex. [electronic resource] by
- Liang, Yi-Lynn
- Khoshouei, Maryam
- Glukhova, Alisa
- Furness, Sebastian G B
- Zhao, Peishen
- Clydesdale, Lachlan
- Koole, Cassandra
- Truong, Tin T
- Thal, David M
- Lei, Saifei
- Radjainia, Mazdak
- Danev, Radostin
- Baumeister, Wolfgang
- Wang, Ming-Wei
- Miller, Laurence J
- Christopoulos, Arthur
- Sexton, Patrick M
- Wootten, Denise
Producer: 20180717
In:
Nature vol. 555
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227.
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Small-molecule-biased formyl peptide receptor agonist compound 17b protects against myocardial ischaemia-reperfusion injury in mice. [electronic resource] by
- Qin, Cheng Xue
- May, Lauren T
- Li, Renming
- Cao, Nga
- Rosli, Sarah
- Deo, Minh
- Alexander, Amy E
- Horlock, Duncan
- Bourke, Jane E
- Yang, Yuan H
- Stewart, Alastair G
- Kaye, David M
- Du, Xiao-Jun
- Sexton, Patrick M
- Christopoulos, Arthur
- Gao, Xiao-Ming
- Ritchie, Rebecca H
Producer: 20181114
In:
Nature communications vol. 8
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228.
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Structure of the adenosine-bound human adenosine A [electronic resource] by
- Draper-Joyce, Christopher J
- Khoshouei, Maryam
- Thal, David M
- Liang, Yi-Lynn
- Nguyen, Anh T N
- Furness, Sebastian G B
- Venugopal, Hariprasad
- Baltos, Jo-Anne
- Plitzko, Jürgen M
- Danev, Radostin
- Baumeister, Wolfgang
- May, Lauren T
- Wootten, Denise
- Sexton, Patrick M
- Glukhova, Alisa
- Christopoulos, Arthur
Producer: 20190114
In:
Nature vol. 558
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229.
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Molecular Mechanisms of Class B GPCR Activation: Insights from Adrenomedullin Receptors. [electronic resource] by
- Garelja, Michael L
- Au, Maggie
- Brimble, Margaret A
- Gingell, Joseph J
- Hendrikse, Erica R
- Lovell, Annie
- Prodan, Nicole
- Sexton, Patrick M
- Siow, Andrew
- Walker, Christopher S
- Watkins, Harriet A
- Williams, Geoffrey M
- Wootten, Denise
- Yang, Sung H
- Harris, Paul W R
- Hay, Debbie L
Publication details: ACS pharmacology & translational science Apr 2020
In:
ACS pharmacology & translational science vol. 3
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230.
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Structural basis of G [electronic resource] by
- Qiao, Anna
- Han, Shuo
- Li, Xinmei
- Li, Zhixin
- Zhao, Peishen
- Dai, Antao
- Chang, Rulve
- Tai, Linhua
- Tan, Qiuxiang
- Chu, Xiaojing
- Ma, Limin
- Thorsen, Thor Seneca
- Reedtz-Runge, Steffen
- Yang, Dehua
- Wang, Ming-Wei
- Sexton, Patrick M
- Wootten, Denise
- Sun, Fei
- Zhao, Qiang
- Wu, Beili
Producer: 20200324
In:
Science (New York, N.Y.) vol. 367
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231.
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Structure-based discovery of selective positive allosteric modulators of antagonists for the M [electronic resource] by
- Korczynska, Magdalena
- Clark, Mary J
- Valant, Celine
- Xu, Jun
- Moo, Ee Von
- Albold, Sabine
- Weiss, Dahlia R
- Torosyan, Hayarpi
- Huang, Weijiao
- Kruse, Andrew C
- Lyda, Brent R
- May, Lauren T
- Baltos, Jo-Anne
- Sexton, Patrick M
- Kobilka, Brian K
- Christopoulos, Arthur
- Shoichet, Brian K
- Sunahara, Roger K
Producer: 20181030
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 115
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232.
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Crystal structure of the M [electronic resource] by
- Vuckovic, Ziva
- Gentry, Patrick R
- Berizzi, Alice E
- Hirata, Kunio
- Varghese, Swapna
- Thompson, Geoff
- van der Westhuizen, Emma T
- Burger, Wessel A C
- Rahmani, Raphaël
- Valant, Celine
- Langmead, Christopher J
- Lindsley, Craig W
- Baell, Jonathan B
- Tobin, Andrew B
- Sexton, Patrick M
- Christopoulos, Arthur
- Thal, David M
Producer: 20200401
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 116
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233.
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The Molecular Control of Calcitonin Receptor Signaling. [electronic resource] by
- Dal Maso, Emma
- Glukhova, Alisa
- Zhu, Yue
- Garcia-Nafria, Javier
- Tate, Christopher G
- Atanasio, Silvia
- Reynolds, Christopher A
- Ramírez-Aportela, Erney
- Carazo, Jose-Maria
- Hick, Caroline A
- Furness, Sebastian G B
- Hay, Debbie L
- Liang, Yi-Lynn
- Miller, Laurence J
- Christopoulos, Arthur
- Wang, Ming-Wei
- Wootten, Denise
- Sexton, Patrick M
Publication details: ACS pharmacology & translational science Feb 2019
In:
ACS pharmacology & translational science vol. 2
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234.
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GPCR structure, function, drug discovery and crystallography: report from Academia-Industry International Conference (UK Royal Society) Chicheley Hall, 1-2 September 2014. [electronic resource] by
- Heifetz, Alexander
- Schertler, Gebhard F X
- Seifert, Roland
- Tate, Christopher G
- Sexton, Patrick M
- Gurevich, Vsevolod V
- Fourmy, Daniel
- Cherezov, Vadim
- Marshall, Fiona H
- Storer, R Ian
- Moraes, Isabel
- Tikhonova, Irina G
- Tautermann, Christofer S
- Hunt, Peter
- Ceska, Tom
- Hodgson, Simon
- Bodkin, Mike J
- Singh, Shweta
- Law, Richard J
- Biggin, Philip C
Producer: 20160331
In:
Naunyn-Schmiedeberg's archives of pharmacology vol. 388
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235.
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Activation of the GLP-1 receptor by a non-peptidic agonist. [electronic resource] by
- Zhao, Peishen
- Liang, Yi-Lynn
- Belousoff, Matthew J
- Deganutti, Giuseppe
- Fletcher, Madeleine M
- Willard, Francis S
- Bell, Michael G
- Christe, Michael E
- Sloop, Kyle W
- Inoue, Asuka
- Truong, Tin T
- Clydesdale, Lachlan
- Furness, Sebastian G B
- Christopoulos, Arthur
- Wang, Ming-Wei
- Miller, Laurence J
- Reynolds, Christopher A
- Danev, Radostin
- Sexton, Patrick M
- Wootten, Denise
Producer: 20200427
In:
Nature vol. 577
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236.
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Discovery and Optimization of Potent and CNS Penetrant M [electronic resource] by
- Bender, Aaron M
- Cho, Hyekyung P
- Nance, Kellie D
- Lingenfelter, Kaelyn S
- Luscombe, Vincent B
- Gentry, Patrick R
- Voigtritter, Karl
- Berizzi, Alice E
- Sexton, Patrick M
- Langmead, Christopher J
- Christopoulos, Arthur
- Locuson, Charles W
- Bridges, Thomas M
- Chang, Sichen
- O'Neill, Jordan C
- Zhan, Xiaoyan
- Niswender, Colleen M
- Jones, Carrie K
- Conn, P Jeffrey
- Lindsley, Craig W
Producer: 20190930
In:
ACS chemical neuroscience vol. 9
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237.
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DREADD Agonist 21 Is an Effective Agonist for Muscarinic-Based DREADDs [electronic resource] by
- Thompson, Karen J
- Khajehali, Elham
- Bradley, Sophie J
- Navarrete, Jovana S
- Huang, Xi Ping
- Slocum, Samuel
- Jin, Jian
- Liu, Jing
- Xiong, Yan
- Olsen, Reid H J
- Diberto, Jeffrey F
- Boyt, Kristen M
- Pina, Melanie M
- Pati, Dipanwita
- Molloy, Colin
- Bundgaard, Christoffer
- Sexton, Patrick M
- Kash, Thomas L
- Krashes, Michael J
- Christopoulos, Arthur
- Roth, Bryan L
- Tobin, Andrew B
Publication details: ACS pharmacology & translational science Sep 2018
In:
ACS pharmacology & translational science vol. 1
Availability: No items available.
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238.
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Biased M1-muscarinic-receptor-mutant mice inform the design of next-generation drugs. [electronic resource] by
- Bradley, Sophie J
- Molloy, Colin
- Valuskova, Paulina
- Dwomoh, Louis
- Scarpa, Miriam
- Rossi, Mario
- Finlayson, Lisa
- Svensson, Kjell A
- Chernet, Eyassu
- Barth, Vanessa N
- Gherbi, Karolina
- Sykes, David A
- Wilson, Caroline A
- Mistry, Rajendra
- Sexton, Patrick M
- Christopoulos, Arthur
- Mogg, Adrian J
- Rosethorne, Elizabeth M
- Sakata, Shuzo
- John Challiss, R A
- Broad, Lisa M
- Tobin, Andrew B
Producer: 20200410
In:
Nature chemical biology vol. 16
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239.
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M1 muscarinic allosteric modulators slow prion neurodegeneration and restore memory loss. [electronic resource] by
- Bradley, Sophie J
- Bourgognon, Julie-Myrtille
- Sanger, Helen E
- Verity, Nicholas
- Mogg, Adrian J
- White, David J
- Butcher, Adrian J
- Moreno, Julie A
- Molloy, Colin
- Macedo-Hatch, Timothy
- Edwards, Jennifer M
- Wess, Jurgen
- Pawlak, Robert
- Read, David J
- Sexton, Patrick M
- Broad, Lisa M
- Steinert, Joern R
- Mallucci, Giovanna R
- Christopoulos, Arthur
- Felder, Christian C
- Tobin, Andrew B
Producer: 20170907
In:
The Journal of clinical investigation vol. 127
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240.
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Update to Our Reader, Reviewer, and Author Communities-April 2020. [electronic resource] by
- Burrows, Cynthia J
- Wang, Shu
- Kim, Hyun Jae
- Meyer, Gerald J
- Schanze, Kirk
- Lee, T Randall
- Lutkenhaus, Jodie L
- Kaplan, David
- Jones, Christopher
- Bertozzi, Carolyn
- Kiessling, Laura
- Mulcahy, Mary Beth
- Lindsley, Craig W
- Finn, M G
- Blum, Joel D
- Kamat, Prashant
- Aldrich, Courtney C
- Rowan, Stuart
- Liotta, Dennis
- Weiss, Paul S
- Zhang, Deqing
- Ganesh, Krishna N
- Sexton, Patrick
- Atwater, Harry A
- Gooding, J Justin
- Allen, David T
- Voigt, Christopher A
- Sweedler, Jonathan
- Schepartz, Alanna
- Rotello, Vincent
- Lecommandoux, Sébastien
- Sturla, Shana J
- Hammes-Schiffer, Sharon
- Buriak, Jillian
- Steed, Jonathan W
- Wu, Hongwei
- Zimmerman, Julie
- Brooks, Bryan
- Savage, Phillip
- Tolman, William
- Hofmann, Thomas F
- Brennecke, Joan F
- Holme, Thomas A
- Merz, Kenneth M
- Scuseria, Gustavo
- Jorgensen, William
- Georg, Gunda I
- Wang, Shaomeng
- Proteau, Philip
- Yates, John R
- Stang, Peter
- Walker, Gilbert C
- Hillmyer, Marc
- Taylor, Lynne S
- Odom, Teri W
- Carreira, Erick
- Rossen, Kai
- Chirik, Paul
- Miller, Scott J
- McCoy, Anne
- Shea, Joan-Emma
- Zanni, Martin
- Murphy, Catherine
- Scholes, Gregory
- Loo, Joseph A
Producer: 20210507
In:
Bioconjugate chemistry vol. 31
Availability: No items available.
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