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Targeting Chk1 in p53-deficient triple-negative breast cancer is therapeutically beneficial in human-in-mouse tumor models. [electronic resource] by
- Ma, Cynthia X
- Cai, Shirong
- Li, Shunqiang
- Ryan, Christine E
- Guo, Zhanfang
- Schaiff, W Timothy
- Lin, Li
- Hoog, Jeremy
- Goiffon, Reece J
- Prat, Aleix
- Aft, Rebecca L
- Ellis, Matthew J
- Piwnica-Worms, Helen
Producer: 20120706
In:
The Journal of clinical investigation vol. 122
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2122.
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2124.
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2125.
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2126.
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Circumvention of Mcl-1-dependent drug resistance by simultaneous Chk1 and MEK1/2 inhibition in human multiple myeloma cells. [electronic resource] by
- Pei, Xin-Yan
- Dai, Yun
- Felthousen, Jessica
- Chen, Shuang
- Takabatake, Yukie
- Zhou, Liang
- Youssefian, Leena E
- Sanderson, Michael W
- Bodie, Wesley W
- Kramer, Lora B
- Orlowski, Robert Z
- Grant, Steven
Producer: 20150209
In:
PloS one vol. 9
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2127.
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Combined PDK1 and CHK1 inhibition is required to kill glioblastoma stem-like cells in vitro and in vivo. [electronic resource] by
- Signore, M
- Pelacchi, F
- di Martino, S
- Runci, D
- Biffoni, M
- Giannetti, S
- Morgante, L
- De Majo, M
- Petricoin, E F
- Stancato, L
- Larocca, L M
- De Maria, R
- Pallini, R
- Ricci-Vitiani, L
Producer: 20141021
In:
Cell death & disease vol. 5
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2128.
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The clinical development candidate CCT245737 is an orally active CHK1 inhibitor with preclinical activity in RAS mutant NSCLC and Eµ-MYC driven B-cell lymphoma. [electronic resource] by
- Walton, Mike I
- Eve, Paul D
- Hayes, Angela
- Henley, Alan T
- Valenti, Melanie R
- De Haven Brandon, Alexis K
- Box, Gary
- Boxall, Kathy J
- Tall, Matthew
- Swales, Karen
- Matthews, Thomas P
- McHardy, Tatiana
- Lainchbury, Michael
- Osborne, James
- Hunter, Jill E
- Perkins, Neil D
- Aherne, G Wynne
- Reader, John C
- Raynaud, Florence I
- Eccles, Suzanne A
- Collins, Ian
- Garrett, Michelle D
Producer: 20161213
In:
Oncotarget vol. 7
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2129.
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ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1. [electronic resource] by
- Zhang, Peijing
- Wei, Yongkun
- Wang, Li
- Debeb, Bisrat G
- Yuan, Yuan
- Zhang, Jinsong
- Yuan, Jingsong
- Wang, Min
- Chen, Dahu
- Sun, Yutong
- Woodward, Wendy A
- Liu, Yongqing
- Dean, Douglas C
- Liang, Han
- Hu, Ye
- Ang, K Kian
- Hung, Mien-Chie
- Chen, Junjie
- Ma, Li
Producer: 20141028
In:
Nature cell biology vol. 16
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2130.
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2131.
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Xanthatin induces G2/M cell cycle arrest and apoptosis in human gastric carcinoma MKN-45 cells. [electronic resource] by
- Zhang, Lei
- Tao, Li
- Ruan, Junshan
- Li, Weidong
- Wu, Yu
- Yan, Linggeng
- Zhang, Feng
- Fan, Fangtian
- Zheng, Shizhong
- Wang, Aiyun
- Lu, Yin
Producer: 20121026
In:
Planta medica vol. 78
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2132.
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A regimen combining the Wee1 inhibitor AZD1775 with HDAC inhibitors targets human acute myeloid leukemia cells harboring various genetic mutations. [electronic resource] by
- Zhou, L
- Zhang, Y
- Chen, S
- Kmieciak, M
- Leng, Y
- Lin, H
- Rizzo, K A
- Dumur, C I
- Ferreira-Gonzalez, A
- Dai, Y
- Grant, S
Producer: 20150604
In:
Leukemia vol. 29
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2133.
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2134.
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Rimonabant inhibits human colon cancer cell growth and reduces the formation of precancerous lesions in the mouse colon. [electronic resource] by
- Santoro, Antonietta
- Pisanti, Simona
- Grimaldi, Claudia
- Izzo, Angelo A
- Borrelli, Francesca
- Proto, Maria C
- Malfitano, Anna M
- Gazzerro, Patrizia
- Laezza, Chiara
- Bifulco, Maurizio
Producer: 20090825
In:
International journal of cancer vol. 125
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2135.
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2136.
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Targeting the replication checkpoint using SCH 900776, a potent and functionally selective CHK1 inhibitor identified via high content screening. [electronic resource] by
- Guzi, Timothy J
- Paruch, Kamil
- Dwyer, Michael P
- Labroli, Marc
- Shanahan, Frances
- Davis, Nicole
- Taricani, Lorena
- Wiswell, Derek
- Seghezzi, Wolfgang
- Penaflor, Ervin
- Bhagwat, Bhagyashree
- Wang, Wei
- Gu, Danling
- Hsieh, Yunsheng
- Lee, Suining
- Liu, Ming
- Parry, David
Producer: 20110801
In:
Molecular cancer therapeutics vol. 10
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2137.
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2138.
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2139.
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2140.
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DNA damage activates a spatially distinct late cytoplasmic cell-cycle checkpoint network controlled by MK2-mediated RNA stabilization. [electronic resource] by
- Reinhardt, H Christian
- Hasskamp, Pia
- Schmedding, Ingolf
- Morandell, Sandra
- van Vugt, Marcel A T M
- Wang, Xiaozhe
- Linding, Rune
- Ong, Shao-En
- Weaver, David
- Carr, Steven A
- Yaffe, Michael B
Producer: 20101101
In:
Molecular cell vol. 40
Availability: No items available.
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