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2041.
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Targeting Mcl-1 enhances DNA replication stress sensitivity to cancer therapy. [electronic resource] by
- Chen, Guo
- Magis, Andrew T
- Xu, Ke
- Park, Dongkyoo
- Yu, David S
- Owonikoko, Taofeek K
- Sica, Gabriel L
- Satola, Sarah W
- Ramalingam, Suresh S
- Curran, Walter J
- Doetsch, Paul W
- Deng, Xingming
Producer: 20190507
In:
The Journal of clinical investigation vol. 128
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2042.
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Triapine potentiates platinum-based combination therapy by disruption of homologous recombination repair. [electronic resource] by
- Ratner, Elena S
- Zhu, Yong-Lian
- Penketh, Philip G
- Berenblum, Julie
- Whicker, Margaret E
- Huang, Pamela H
- Lee, Yashang
- Ishiguro, Kimiko
- Zhu, Rui
- Sartorelli, Alan C
- Lin, Z Ping
Producer: 20160817
In:
British journal of cancer vol. 114
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2043.
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The Combination of the PARP Inhibitor Olaparib and the WEE1 Inhibitor AZD1775 as a New Therapeutic Option for Small Cell Lung Cancer. [electronic resource] by
- Lallo, Alice
- Frese, Kristopher K
- Morrow, Christopher J
- Sloane, Robert
- Gulati, Sakshi
- Schenk, Maximillian W
- Trapani, Francesca
- Simms, Nicole
- Galvin, Melanie
- Brown, Stewart
- Hodgkinson, Cassandra L
- Priest, Lynsey
- Hughes, Adina
- Lai, Zhongwu
- Cadogan, Elaine
- Khandelwal, Garima
- Simpson, Kathryn L
- Miller, Crispin
- Blackhall, Fiona
- O'Connor, Mark J
- Dive, Caroline
Producer: 20191118
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 24
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2044.
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Phase I/IIa study of concomitant radiotherapy with olaparib and temozolomide in unresectable or partially resectable glioblastoma: OLA-TMZ-RTE-01 trial protocol. [electronic resource] by
- Lesueur, Paul
- Lequesne, Justine
- Grellard, Jean-Michel
- Dugué, Audrey
- Coquan, Elodie
- Brachet, Pierre-Emmanuel
- Geffrelot, Julien
- Kao, William
- Emery, Evelyne
- Berro, David Hassanein
- Castera, Laurent
- Goardon, Nicolas
- Lacroix, Joëlle
- Lange, Marie
- Capel, Aurélie
- Leconte, Alexandra
- Andre, Benoit
- Léger, Angélique
- Lelaidier, Anaïs
- Clarisse, Bénédicte
- Stefan, Dinu
Producer: 20190701
In:
BMC cancer vol. 19
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2045.
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DNA damage-induced PARP1 activation confers cardiomyocyte dysfunction through NAD [electronic resource] by
- Zhang, Deli
- Hu, Xu
- Li, Jin
- Liu, Jia
- Baks-Te Bulte, Luciënne
- Wiersma, Marit
- Malik, Noor-Ul-Ann
- van Marion, Denise M S
- Tolouee, Marziyeh
- Hoogstra-Berends, Femke
- Lanters, Eva A H
- van Roon, Arie M
- de Vries, Antoine A F
- Pijnappels, Daniël A
- de Groot, Natasja M S
- Henning, Robert H
- Brundel, Bianca J J M
Producer: 20190404
In:
Nature communications vol. 10
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2046.
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Transcriptome analysis reveals overlap in fusion genes in a phase I clinical cohort of TNBC and HGSOC patients treated with buparlisib and olaparib. [electronic resource] by
- Eismann, Julia
- Heng, Yujing J
- Waldschmidt, Johannes M
- Vlachos, Ioannis S
- Gray, Kathryn P
- Matulonis, Ursula A
- Konstantinopoulos, Panagiotis A
- Murphy, Charles J
- Nabavi, Sheida
- Wulf, Gerburg M
Producer: 20200224
In:
Journal of cancer research and clinical oncology vol. 146
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2047.
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Olaparib for Metastatic Castration-Resistant Prostate Cancer. [electronic resource] by
- de Bono, Johann
- Mateo, Joaquin
- Fizazi, Karim
- Saad, Fred
- Shore, Neal
- Sandhu, Shahneen
- Chi, Kim N
- Sartor, Oliver
- Agarwal, Neeraj
- Olmos, David
- Thiery-Vuillemin, Antoine
- Twardowski, Przemyslaw
- Mehra, Niven
- Goessl, Carsten
- Kang, Jinyu
- Burgents, Joseph
- Wu, Wenting
- Kohlmann, Alexander
- Adelman, Carrie A
- Hussain, Maha
Producer: 20200603
In:
The New England journal of medicine vol. 382
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2048.
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2049.
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2050.
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2051.
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2052.
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BRCA1, PARP1 and γH2AX in acute myeloid leukemia: Role as biomarkers of response to the PARP inhibitor olaparib. [electronic resource] by
- Faraoni, Isabella
- Compagnone, Mirco
- Lavorgna, Serena
- Angelini, Daniela Francesca
- Cencioni, Maria Teresa
- Piras, Eleonora
- Panetta, Paola
- Ottone, Tiziana
- Dolci, Susanna
- Venditti, Adriano
- Graziani, Grazia
- Lo-Coco, Francesco
Producer: 20150916
In:
Biochimica et biophysica acta vol. 1852
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2053.
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Olaparib tablet formulation: effect of food on the pharmacokinetics after oral dosing in patients with advanced solid tumours. [electronic resource] by
- Plummer, Ruth
- Swaisland, Helen
- Leunen, Karin
- van Herpen, Carla M L
- Jerusalem, Guy
- De Grève, Jacques
- Lolkema, Martijn P
- Soetekouw, Patricia
- Mau-Sørensen, Morten
- Nielsen, Dorte
- Spicer, James
- Fielding, Anitra
- So, Karen
- Bannister, Wendy
- Molife, L Rhoda
Producer: 20151217
In:
Cancer chemotherapy and pharmacology vol. 76
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2054.
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2055.
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Olaparib combined with abiraterone in patients with metastatic castration-resistant prostate cancer: a randomised, double-blind, placebo-controlled, phase 2 trial. [electronic resource] by
- Clarke, Noel
- Wiechno, Pawel
- Alekseev, Boris
- Sala, Nuria
- Jones, Robert
- Kocak, Ivo
- Chiuri, Vincenzo Emanuele
- Jassem, Jacek
- Fléchon, Aude
- Redfern, Charles
- Goessl, Carsten
- Burgents, Joseph
- Kozarski, Robert
- Hodgson, Darren
- Learoyd, Maria
- Saad, Fred
Producer: 20190408
In:
The Lancet. Oncology vol. 19
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2056.
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2057.
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2058.
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MRI monitoring of tumor response to a novel VEGF tyrosine kinase inhibitor in an experimental breast cancer model. [electronic resource] by
- Turetschek, Karl
- Preda, Anda
- Floyd, Eugenia
- Shames, David M
- Novikov, Viktor
- Roberts, Timothy P L
- Wood, Jeanette M
- Fu, Yanjun
- Carter, Wayne O
- Brasch, Robert C
Producer: 20030225
In:
Academic radiology vol. 9 Suppl 2
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2059.
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The vascular endothelial growth factor receptor tyrosine kinase inhibitors vatalanib and pazopanib potently induce apoptosis in chronic lymphocytic leukemia cells in vitro and in vivo. [electronic resource] by
- Paesler, Julian
- Gehrke, Iris
- Gandhirajan, Rajesh Kumar
- Filipovich, Alexandra
- Hertweck, Magdalena
- Erdfelder, Felix
- Uhrmacher, Sabrina
- Poll-Wolbeck, Simon Jonas
- Hallek, Michael
- Kreuzer, Karl-Anton
Producer: 20100901
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 16
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2060.
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