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Multiparameter Lead Optimization to Give an Oral Checkpoint Kinase 1 (CHK1) Inhibitor Clinical Candidate: (R)-5-((4-((Morpholin-2-ylmethyl)amino)-5-(trifluoromethyl)pyridin-2-yl)amino)pyrazine-2-carbonitrile (CCT245737). [electronic resource] by
- Osborne, James D
- Matthews, Thomas P
- McHardy, Tatiana
- Proisy, Nicolas
- Cheung, Kwai-Ming J
- Lainchbury, Michael
- Brown, Nathan
- Walton, Michael I
- Eve, Paul D
- Boxall, Katherine J
- Hayes, Angela
- Henley, Alan T
- Valenti, Melanie R
- De Haven Brandon, Alexis K
- Box, Gary
- Jamin, Yann
- Robinson, Simon P
- Westwood, Isaac M
- van Montfort, Rob L M
- Leonard, Philip M
- Lamers, Marieke B A C
- Reader, John C
- Aherne, G Wynne
- Raynaud, Florence I
- Eccles, Suzanne A
- Garrett, Michelle D
- Collins, Ian
Producer: 20170606
In:
Journal of medicinal chemistry vol. 59
Availability: No items available.
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