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201.
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High throughput, quantitative analysis of human osteoclast differentiation and activity. [electronic resource] by
- Diepenhorst, Natalie A
- Nowell, Cameron J
- Rueda, Patricia
- Henriksen, Kim
- Pierce, Tracie
- Cook, Anna E
- Pastoureau, Philippe
- Sabatini, Massimo
- Charman, William N
- Christopoulos, Arthur
- Summers, Roger J
- Sexton, Patrick M
- Langmead, Christopher J
Producer: 20170508
In:
Analytical biochemistry vol. 519
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202.
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The role of kinetic context in apparent biased agonism at GPCRs. [electronic resource] by
- Klein Herenbrink, Carmen
- Sykes, David A
- Donthamsetti, Prashant
- Canals, Meritxell
- Coudrat, Thomas
- Shonberg, Jeremy
- Scammells, Peter J
- Capuano, Ben
- Sexton, Patrick M
- Charlton, Steven J
- Javitch, Jonathan A
- Christopoulos, Arthur
- Lane, J Robert
Producer: 20160712
In:
Nature communications vol. 7
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203.
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Automatic local resolution-based sharpening of cryo-EM maps. [electronic resource] by
- Ramírez-Aportela, Erney
- Vilas, Jose Luis
- Glukhova, Alisa
- Melero, Roberto
- Conesa, Pablo
- Martínez, Marta
- Maluenda, David
- Mota, Javier
- Jiménez, Amaya
- Vargas, Javier
- Marabini, Roberto
- Sexton, Patrick M
- Carazo, Jose Maria
- Sorzano, Carlos Oscar S
Producer: 20200917
In:
Bioinformatics (Oxford, England) vol. 36
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204.
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Drug-receptor kinetics and sigma-1 receptor affinity differentiate clinically evaluated histamine H [electronic resource] by
- Riddy, Darren M
- Cook, Anna E
- Shackleford, David M
- Pierce, Tracie L
- Mocaer, Elisabeth
- Mannoury la Cour, Clotilde
- Sors, Aurore
- Charman, William N
- Summers, Roger J
- Sexton, Patrick M
- Christopoulos, Arthur
- Langmead, Christopher J
Producer: 20190304
In:
Neuropharmacology vol. 144
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205.
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Rational development of a high-affinity secretin receptor antagonist. [electronic resource] by
- Dong, Maoqing
- Harikumar, Kaleeckal G
- Raval, Sweta R
- Milburn, Juliana E
- Clark, Carolyn
- Alcala-Torano, Rafael
- Mobarec, Juan C
- Reynolds, Christopher A
- Ghirlanda, Giovanna
- Christopoulos, Arthur
- Wootten, Denise
- Sexton, Patrick M
- Miller, Laurence J
Producer: 20201214
In:
Biochemical pharmacology vol. 177
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206.
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Extracellular loops 2 and 3 of the calcitonin receptor selectively modify agonist binding and efficacy. [electronic resource] by
- Dal Maso, Emma
- Zhu, Yue
- Pham, Vi
- Reynolds, Christopher A
- Deganutti, Giuseppe
- Hick, Caroline A
- Yang, Dehua
- Christopoulos, Arthur
- Hay, Debbie L
- Wang, Ming-Wei
- Sexton, Patrick M
- Furness, Sebastian G B
- Wootten, Denise
Producer: 20190109
In:
Biochemical pharmacology vol. 150
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207.
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Vascular and molecular pharmacology of the metabolically stable CGRP analogue, SAX. [electronic resource] by
- Sheykhzade, Majid
- Abdolalizadeh, Bahareh
- Koole, Cassandra
- Pickering, Darryl Scott
- Dreisig, Karin
- Johansson, Sara Ellinor
- Abboud, Balsam Kadri
- Dreier, Rasmus
- Berg, Jais Oliver
- Jeppesen, Jørgen Lykke
- Sexton, Patrick M
- Edvinsson, Lars
- Wootten, Denise
- Sams, Anette
Producer: 20181002
In:
European journal of pharmacology vol. 829
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208.
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O-GlcNAc Engineering of GPCR Peptide-Agonists Improves Their Stability and in Vivo Activity. [electronic resource] by
- Levine, Paul M
- Balana, Aaron T
- Sturchler, Emmanuel
- Koole, Cassandra
- Noda, Hiroshi
- Zarzycka, Barbara
- Daley, Eileen J
- Truong, Tin T
- Katritch, Vsevolod
- Gardella, Thomas J
- Wootten, Denise
- Sexton, Patrick M
- McDonald, Patricia
- Pratt, Matthew R
Producer: 20200923
In:
Journal of the American Chemical Society vol. 141
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209.
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Functional selectivity and classical concepts of quantitative pharmacology. [electronic resource] by
- Urban, Jonathan D
- Clarke, William P
- von Zastrow, Mark
- Nichols, David E
- Kobilka, Brian
- Weinstein, Harel
- Javitch, Jonathan A
- Roth, Bryan L
- Christopoulos, Arthur
- Sexton, Patrick M
- Miller, Keith J
- Spedding, Michael
- Mailman, Richard B
Producer: 20070212
In:
The Journal of pharmacology and experimental therapeutics vol. 320
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210.
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6-Phenylpyrimidin-4-ones as Positive Allosteric Modulators at the M [electronic resource] by
- Jörg, Manuela
- van der Westhuizen, Emma T
- Khajehali, Elham
- Burger, Wessel A C
- White, Jonathan M
- Choy, Kwok H C
- Tobin, Andrew B
- Sexton, Patrick M
- Valant, Celine
- Capuano, Ben
- Christopoulos, Arthur
- Scammells, Peter J
Producer: 20200305
In:
ACS chemical neuroscience vol. 10
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211.
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Glucagon-Like Peptide-1 and Its Class B G Protein-Coupled Receptors: A Long March to Therapeutic Successes. [electronic resource] by
- Graaf, Chris de
- Donnelly, Dan
- Wootten, Denise
- Lau, Jesper
- Sexton, Patrick M
- Miller, Laurence J
- Ahn, Jung-Mo
- Liao, Jiayu
- Fletcher, Madeleine M
- Yang, Dehua
- Brown, Alastair J H
- Zhou, Caihong
- Deng, Jiejie
- Wang, Ming-Wei
Producer: 20170316
In:
Pharmacological reviews vol. 68
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212.
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Deconvoluting the Molecular Control of Binding and Signaling at the Amylin 3 Receptor: RAMP3 Alters Signal Propagation through Extracellular Loops of the Calcitonin Receptor. [electronic resource] by
- Pham, Vi
- Zhu, Yue
- Dal Maso, Emma
- Reynolds, Christopher A
- Deganutti, Giuseppe
- Atanasio, Silvia
- Hick, Caroline A
- Yang, Dehua
- Christopoulos, Arthur
- Hay, Debbie L
- Furness, Sebastian G B
- Wang, Ming-Wei
- Wootten, Denise
- Sexton, Patrick M
Publication details: ACS pharmacology & translational science Jun 2019
In:
ACS pharmacology & translational science vol. 2
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213.
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Crystal structures of the M1 and M4 muscarinic acetylcholine receptors. [electronic resource] by
- Thal, David M
- Sun, Bingfa
- Feng, Dan
- Nawaratne, Vindhya
- Leach, Katie
- Felder, Christian C
- Bures, Mark G
- Evans, David A
- Weis, William I
- Bachhawat, Priti
- Kobilka, Tong Sun
- Sexton, Patrick M
- Kobilka, Brian K
- Christopoulos, Arthur
Producer: 20160412
In:
Nature vol. 531
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214.
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Divergent effects of strontium and calcium-sensing receptor positive allosteric modulators (calcimimetics) on human osteoclast activity. [electronic resource] by
- Diepenhorst, Natalie A
- Leach, Katie
- Keller, Andrew N
- Rueda, Patricia
- Cook, Anna E
- Pierce, Tracie L
- Nowell, Cameron
- Pastoureau, Philippe
- Sabatini, Massimo
- Summers, Roger J
- Charman, William N
- Sexton, Patrick M
- Christopoulos, Arthur
- Langmead, Christopher J
Producer: 20190923
In:
British journal of pharmacology vol. 175
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215.
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Toward a Structural Understanding of Class B GPCR Peptide Binding and Activation. [electronic resource] by
- Liang, Yi-Lynn
- Belousoff, Matthew J
- Zhao, Peishen
- Koole, Cassandra
- Fletcher, Madeleine M
- Truong, Tin T
- Julita, Villy
- Christopoulos, George
- Xu, H Eric
- Zhang, Yan
- Khoshouei, Maryam
- Christopoulos, Arthur
- Danev, Radostin
- Sexton, Patrick M
- Wootten, Denise
Producer: 20200427
In:
Molecular cell vol. 77
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216.
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Cryo-EM structure of the active, G [electronic resource] by
- Liang, Yi-Lynn
- Khoshouei, Maryam
- Deganutti, Giuseppe
- Glukhova, Alisa
- Koole, Cassandra
- Peat, Thomas S
- Radjainia, Mazdak
- Plitzko, Jürgen M
- Baumeister, Wolfgang
- Miller, Laurence J
- Hay, Deborah L
- Christopoulos, Arthur
- Reynolds, Christopher A
- Wootten, Denise
- Sexton, Patrick M
Producer: 20190318
In:
Nature vol. 561
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217.
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Structural basis for modulation of a G-protein-coupled receptor by allosteric drugs. [electronic resource] by
- Dror, Ron O
- Green, Hillary F
- Valant, Celine
- Borhani, David W
- Valcourt, James R
- Pan, Albert C
- Arlow, Daniel H
- Canals, Meritxell
- Lane, J Robert
- Rahmani, Raphaël
- Baell, Jonathan B
- Sexton, Patrick M
- Christopoulos, Arthur
- Shaw, David E
Producer: 20131127
In:
Nature vol. 503
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218.
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Structure and Dynamics of Adrenomedullin Receptors AM [electronic resource] by
- Liang, Yi-Lynn
- Belousoff, Matthew J
- Fletcher, Madeleine M
- Zhang, Xin
- Khoshouei, Maryam
- Deganutti, Giuseppe
- Koole, Cassandra
- Furness, Sebastian G B
- Miller, Laurence J
- Hay, Debbie L
- Christopoulos, Arthur
- Reynolds, Christopher A
- Danev, Radostin
- Wootten, Denise
- Sexton, Patrick M
Publication details: ACS pharmacology & translational science Apr 2020
In:
ACS pharmacology & translational science vol. 3
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219.
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The Extracellular Surface of the GLP-1 Receptor Is a Molecular Trigger for Biased Agonism. [electronic resource] by
- Wootten, Denise
- Reynolds, Christopher A
- Smith, Kevin J
- Mobarec, Juan C
- Koole, Cassandra
- Savage, Emilia E
- Pabreja, Kavita
- Simms, John
- Sridhar, Rohan
- Furness, Sebastian G B
- Liu, Mengjie
- Thompson, Philip E
- Miller, Laurence J
- Christopoulos, Arthur
- Sexton, Patrick M
Producer: 20170110
In:
Cell vol. 165
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220.
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Murine GPRC6A Mediates Cellular Responses to L-Amino Acids, but Not Osteocalcin Variants. [electronic resource] by
- Rueda, Patricia
- Harley, Elizabeth
- Lu, Yao
- Stewart, Gregory D
- Fabb, Stewart
- Diepenhorst, Natalie
- Cremers, Béatrice
- Rouillon, Marie-Hélène
- Wehrle, Isabelle
- Geant, Anne
- Lamarche, Gwladys
- Leach, Katie
- Charman, William N
- Christopoulos, Arthur
- Summers, Roger J
- Sexton, Patrick M
- Langmead, Christopher J
Producer: 20160726
In:
PloS one vol. 11
Availability: No items available.
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