Your search returned 38 results.

Results
	21.	A novel series of DNA triple helix-binding ligands. [electronic resource] by Fox, K R Thurston, D E Jenkins, T C Varvaresou, A Tsotinis, A Siatra-Papastaikoudi, T Producer: 19960910 In: Biochemical and biophysical research communications vol. 224 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	22.	Fludarabine-mediated suppression of the excision repair enzyme ERCC1 contributes to the cytotoxic synergy with the DNA minor groove crosslinking agent SJG-136 (NSC 694501) in chronic lymphocytic leukaemia cells. [electronic resource] by Pepper, C Lowe, H Fegan, C Thurieau, C Thurston, D E Hartley, J A Delavault, P Producer: 20071127 In: British journal of cancer vol. 97 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	23.	O,S,S,-trimethyl phosphorodithioate-induced lung damage in rats and mice. [electronic resource] by Kehrer, J P Klein-Szanto, A J Thurston, D E Lindenschmidt, R C Witschi, H R Producer: 19860818 In: Toxicology and applied pharmacology vol. 84 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	24.	Preclinical pharmacology of the pyrrolobenzodiazepine (PBD) monomer DRH-417 (NSC 709119). [electronic resource] by Burger, A M Loadman, P M Thurston, D E Schultz, R Fiebig, H H Bibby, M C Producer: 20070410 In: Journal of chemotherapy (Florence, Italy) vol. 19 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	25.	ABCB1 genetic polymorphism influences the pharmacology of the new pyrrolobenzodiazepine derivative SJG-136. [electronic resource] by Aird, R E Thomson, M Macpherson, J S Thurston, D E Jodrell, D I Guichard, S M Producer: 20081211 In: The pharmacogenomics journal vol. 8 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	26.	Design and synthesis of novel pyrrolobenzodiazepine (PBD) prodrugs for ADEPT and GDEPT. [electronic resource] by Sagnou, M J Howard, P W Gregson, S J Eno-Amooquaye, E Burke, P J Thurston, D E Producer: 20010329 In: Bioorganic & medicinal chemistry letters vol. 10 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	27.	Synthesis of the first example of a C2-C3/C2'-C3'-endo unsaturated pyrrolo[2,1-c][1,4]benzodiazepine dimer. [electronic resource] by Gregson, S J Howard, P W Corcoran, K E Jenkins, T C Kelland, L R Thurston, D E Producer: 20020109 In: Bioorganic & medicinal chemistry letters vol. 11 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	28.	Effect of C2/C3-endo unsaturation on the cytotoxicity and DNA-binding reactivity of pyrrolo[2,1-c][1,4]benzodiazepines. [electronic resource] by Gregson, S J Howard, P W Barcella, S Nakamya, A Jenkins, T C Kelland, L R Thurston, D E Producer: 20010118 In: Bioorganic & medicinal chemistry letters vol. 10 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	29.	Inhibition of bacteriophage T7 RNA polymerase in vitro transcription by DNA-binding pyrrolo[2,1-c][1,4]benzodiazepines. [electronic resource] by Puvvada, M S Forrow, S A Hartley, J A Stephenson, P Gibson, I Jenkins, T C Thurston, D E Producer: 19970326 In: Biochemistry vol. 36 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	30.	DNA cross-linking and sequence selectivity of aziridinylbenzoquinones: a unique reaction at 5'-GC-3' sequences with 2,5-diaziridinyl-1,4-benzoquinone upon reduction. [electronic resource] by Hartley, J A Berardini, M Ponti, M Gibson, N W Thompson, A S Thurston, D E Hoey, B M Butler, J Producer: 19920130 In: Biochemistry vol. 30 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	31.	The non-covalent interaction of pyrrolo[2, 1-c] [1, 4]benzodiazepine-5, 11-diones with DNA. [electronic resource] by Jones, G B Davey, C L Jenkins, T C Kamal, A Kneale, G G Neidle, S Webster, G D Thurston, D E Producer: 19901026 In: Anti-cancer drug design vol. 5 Availability: No items available. Save to lists Add to cart (remove)
	32.	Design, synthesis, and evaluation of a novel pyrrolobenzodiazepine DNA-interactive agent with highly efficient cross-linking ability and potent cytotoxicity. [electronic resource] by Gregson, S J Howard, P W Hartley, J A Brooks, N A Adams, L J Jenkins, T C Kelland, L R Thurston, D E Producer: 20010419 In: Journal of medicinal chemistry vol. 44 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	33.	Design, synthesis, and evaluation of a novel sequence-selective epoxide-containing DNA cross-linking agent based on the pyrrolo[2, 1-c][1,4]benzodiazepine system. [electronic resource] by Wilson, S C Howard, P W Forrow, S M Hartley, J A Adams, L J Jenkins, T C Kelland, L R Thurston, D E Producer: 19991104 In: Journal of medicinal chemistry vol. 42 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	34.	Design, synthesis and biological activity of a pyrrolo [2,1-c][1,4]benzodiazepine (PBD)-distamycin hybrid. [electronic resource] by Baraldi, P G Cacciari, B Guiotto, A Leoni, A Romagnoli, R Spalluto, G Mongelli, N Howard, P W Thurston, D E Bianchi, N Gambari, R Producer: 19990126 In: Bioorganic & medicinal chemistry letters vol. 8 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	35.	Effect of C2-exo unsaturation on the cytotoxicity and DNA-binding reactivity of pyrrolo[2,1-c][1,4]benzodiazepines. [electronic resource] by Gregson, S J Howard, P W Corcoran, K E Barcella, S Yasin, M M Hurst, A A Jenkins, T C Kelland, L R Thurston, D E Producer: 20010118 In: Bioorganic & medicinal chemistry letters vol. 10 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	36.	Pyrrolo[1,4]benzodiazepine antitumor antibiotics: relationship of DNA alkylation and sequence specificity to the biological activity of natural and synthetic compounds. [electronic resource] by Hurley, L H Reck, T Thurston, D E Langley, D R Holden, K G Hertzberg, R P Hoover, J R Gallagher, G Faucette, L F Mong, S M Producer: 19920309 In: Chemical research in toxicology vol. 1 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	37.	Effect of A-ring modifications on the DNA-binding behavior and cytotoxicity of pyrrolo[2,1-c][1,4]benzodiazepines. [electronic resource] by Thurston, D E Bose, D S Howard, P W Jenkins, T C Leoni, A Baraldi, P G Guiotto, A Cacciari, B Kelland, L R Foloppe, M P Rault, S Producer: 19990624 In: Journal of medicinal chemistry vol. 42 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)
	38.	Synthesis, in vitro antiproliferative activity, and DNA-binding properties of hybrid molecules containing pyrrolo[2,1-c][1, 4]benzodiazepine and minor-groove-binding oligopyrrole carriers. [electronic resource] by Baraldi, P G Balboni, G Cacciari, B Guiotto, A Manfredini, S Romagnoli, R Spalluto, G Thurston, D E Howard, P W Bianchi, N Rutigliano, C Mischiati, C Gambari, R Producer: 20000124 In: Journal of medicinal chemistry vol. 42 Online resources: Available from publisher's website Availability: No items available. Save to lists Add to cart (remove)