Results
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21.
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Discovery of amido-benzisoxazoles as potent c-Kit inhibitors. [electronic resource] by
- Kunz, Roxanne K
- Rumfelt, Shannon
- Chen, Ning
- Zhang, Dawei
- Tasker, Andrew S
- Bürli, Roland
- Hungate, Randall
- Yu, Violeta
- Nguyen, Yen
- Whittington, Douglas A
- Meagher, Kristin L
- Plant, Matthew
- Tudor, Yanyan
- Schrag, Michael
- Xu, Yang
- Ng, Gordon Y
- Hu, Essa
Producer: 20081014
In:
Bioorganic & medicinal chemistry letters vol. 18
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22.
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c-Met inhibitors with novel binding mode show activity against several hereditary papillary renal cell carcinoma-related mutations. [electronic resource] by
- Bellon, Steven F
- Kaplan-Lefko, Paula
- Yang, Yajing
- Zhang, Yihong
- Moriguchi, Jodi
- Rex, Karen
- Johnson, Carol W
- Rose, Paul E
- Long, Alexander M
- O'Connor, Anne B
- Gu, Yan
- Coxon, Angela
- Kim, Tae-Seong
- Tasker, Andrew
- Burgess, Teresa L
- Dussault, Isabelle
Producer: 20080402
In:
The Journal of biological chemistry vol. 283
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23.
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Discovery of 5-(1H-indol-5-yl)-1,3,4-thiadiazol-2-amines as potent PIM inhibitors. [electronic resource] by
- Wu, Bin
- Wang, Hui-Ling
- Cee, Victor J
- Lanman, Brian A
- Nixey, Thomas
- Pettus, Liping
- Reed, Anthony B
- Wurz, Ryan P
- Guerrero, Nadia
- Sastri, Christine
- Winston, Jeff
- Lipford, J Russell
- Lee, Matthew R
- Mohr, Christopher
- Andrews, Kristin L
- Tasker, Andrew S
Producer: 20151016
In:
Bioorganic & medicinal chemistry letters vol. 25
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24.
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Discovery and evaluation of 7-alkyl-1,5-bis-aryl-pyrazolopyridinones as highly potent, selective, and orally efficacious inhibitors of p38alpha mitogen-activated protein kinase. [electronic resource] by
- Pettus, Liping H
- Wurz, Ryan P
- Xu, Shimin
- Herberich, Brad
- Henkle, Bradley
- Liu, Qiurong
- McBride, Helen J
- Mu, Sharon
- Plant, Matthew H
- Saris, Christiaan J M
- Sherman, Lisa
- Wong, Lu Min
- Chmait, Samer
- Lee, Matthew R
- Mohr, Christopher
- Hsieh, Faye
- Tasker, Andrew S
Producer: 20100510
In:
Journal of medicinal chemistry vol. 53
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25.
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N-Aryl-gamma-lactams as integrin alphavbeta3 antagonists. [electronic resource] by
- Xi, Ning
- Arvedson, Stephen
- Eisenberg, Shawn
- Han, Nianhe
- Handley, Michael
- Huang, Liang
- Huang, Qi
- Kiselyov, Alexander
- Liu, Qingyian
- Lu, Yuelie
- Nunez, Gladys
- Osslund, Timothy
- Powers, David
- Tasker, Andrew S
- Wang, Ling
- Xiang, Tingjian
- Xu, Shimin
- Zhang, Jiandong
- Zhu, Jiawang
- Kendall, Richard
- Dominguez, Celia
Producer: 20050104
In:
Bioorganic & medicinal chemistry letters vol. 14
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26.
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The discovery of novel 3-(pyrazin-2-yl)-1H-indazoles as potent pan-Pim kinase inhibitors. [electronic resource] by
- Wang, Hui-Ling
- Cee, Victor J
- Chavez, Frank
- Lanman, Brian A
- Reed, Anthony B
- Wu, Bin
- Guerrero, Nadia
- Lipford, J Russell
- Sastri, Christine
- Winston, Jeff
- Andrews, Kristin L
- Huang, Xin
- Lee, Matthew R
- Mohr, Christopher
- Xu, Yang
- Zhou, Yihong
- Tasker, Andrew S
Producer: 20151016
In:
Bioorganic & medicinal chemistry letters vol. 25
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27.
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Discovery of aryl aminoquinazoline pyridones as potent, selective, and orally efficacious inhibitors of receptor tyrosine kinase c-Kit. [electronic resource] by
- Hu, Essa
- Tasker, Andrew
- White, Ryan D
- Kunz, Roxanne K
- Human, Jason
- Chen, Ning
- Bürli, Roland
- Hungate, Randall
- Novak, Perry
- Itano, Andrea
- Zhang, Xuxia
- Yu, Violeta
- Nguyen, Yen
- Tudor, Yanyan
- Plant, Matthew
- Flynn, Shaun
- Xu, Yang
- Meagher, Kristin L
- Whittington, Douglas A
- Ng, Gordon Y
Producer: 20080728
In:
Journal of medicinal chemistry vol. 51
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28.
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Isoform-selective thiazolo[5,4-b]pyridine S1P1 agonists possessing acyclic amino carboxylate head-groups. [electronic resource] by
- Reed, Anthony B
- Lanman, Brian A
- Neira, Susana
- Harrington, Paul E
- Sham, Kelvin K C
- Frohn, Mike
- Pickrell, Alexander J
- Tasker, Andrew S
- Gore, Anu
- Fiorino, Mike
- Itano, Andrea
- McElvain, Michele
- Middleton, Scot
- Morrison, Henry
- Xu, Han
- Xu, Yang
- Wong, Min
- Cee, Victor J
Producer: 20120531
In:
Bioorganic & medicinal chemistry letters vol. 22
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29.
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(4-Piperidinylphenyl)aminoethyl amides as a novel class of non-covalent cathepsin K inhibitors. [electronic resource] by
- Kim, Tae-Seong
- Hague, Andrew B
- Lee, Tony I
- Lian, Brian
- Tegley, Christopher M
- Wang, Xianghong
- Burgess, Teresa L
- Qian, Yi-Xin
- Ross, Sandra
- Tagari, Philip
- Lin, Chi-Hwei
- Mayeda, Carol
- Dao, Jennifer
- Jordan, Steven
- Mohr, Christopher
- Cheetham, Janet
- Viswanadhan, Vellarkad
- Tasker, Andrew S
Producer: 20040827
In:
Bioorganic & medicinal chemistry letters vol. 14
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30.
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AMG 706, an oral, multikinase inhibitor that selectively targets vascular endothelial growth factor, platelet-derived growth factor, and kit receptors, potently inhibits angiogenesis and induces regression in tumor xenografts. [electronic resource] by
- Polverino, Anthony
- Coxon, Angela
- Starnes, Charlie
- Diaz, Zobedia
- DeMelfi, Thomas
- Wang, Ling
- Bready, James
- Estrada, Juan
- Cattley, Russell
- Kaufman, Stephen
- Chen, Danlin
- Gan, Yongmei
- Kumar, Gondi
- Meyer, James
- Neervannan, Sesha
- Alva, Gonzalo
- Talvenheimo, Jane
- Montestruque, Silvia
- Tasker, Andrew
- Patel, Vinod
- Radinsky, Robert
- Kendall, Richard
Producer: 20071126
In:
Cancer research vol. 66
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31.
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Discovery of N-phenyl nicotinamides as potent inhibitors of Kdr. [electronic resource] by
- Dominguez, Celia
- Smith, Leon
- Huang, Qi
- Yuan, Chester
- Ouyang, Xiaohu
- Cai, Lynn
- Chen, Paul
- Kim, Joseph
- Harvey, Timothy
- Syed, Rashid
- Kim, Tae-Seong
- Tasker, Andrew
- Wang, Ling
- Zhang, Michael
- Coxon, Angela
- Bready, James
- Starnes, Charles
- Chen, Danlin
- Gan, Yongmei
- Neervannan, Sesha
- Kumar, Gondi
- Polverino, Anthony
- Kendall, Richard
Producer: 20080205
In:
Bioorganic & medicinal chemistry letters vol. 17
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32.
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2-Aminothiadiazole inhibitors of AKT1 as potential cancer therapeutics. [electronic resource] by
- Zeng, Qingping
- Bourbeau, Matthew P
- Wohlhieter, G Erich
- Yao, Guomin
- Monenschein, Holger
- Rider, James T
- Lee, Matthew R
- Zhang, Shiwen
- Lofgren, Julie
- Freeman, Daniel
- Li, Chun
- Tominey, Elizabeth
- Huang, Xin
- Hoffman, Douglas
- Yamane, Harvey
- Tasker, Andrew S
- Dominguez, Celia
- Viswanadhan, Vellarkad N
- Hungate, Randall
- Zhang, Xiaoling
Producer: 20100527
In:
Bioorganic & medicinal chemistry letters vol. 20
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33.
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Optimization of a Potent, Orally Active S1P1 Agonist Containing a Quinolinone Core. [electronic resource] by
- Harrington, Paul E
- Croghan, Michael D
- Fotsch, Christopher
- Frohn, Mike
- Lanman, Brian A
- Pennington, Lewis D
- Pickrell, Alexander J
- Reed, Anthony B
- Sham, Kelvin K C
- Tasker, Andrew
- Arnett, Heather A
- Fiorino, Michael
- Lee, Matthew R
- McElvain, Michele
- Morrison, Henry G
- Xu, Han
- Xu, Yang
- Zhang, Xuxia
- Wong, Min
- Cee, Victor J
Producer: 20140605
In:
ACS medicinal chemistry letters vol. 3
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34.
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Phosphoinositide-3-kinase inhibitors: evaluation of substituted alcohols as replacements for the piperazine sulfonamide portion of AMG 511. [electronic resource] by
- Lanman, Brian A
- Reed, Anthony B
- Cee, Victor J
- Hong, Fang-Tsao
- Pettus, Liping H
- Wurz, Ryan P
- Andrews, Kristin L
- Jiang, Jian
- McCarter, John D
- Mullady, Erin L
- San Miguel, Tisha
- Subramanian, Raju
- Wang, Ling
- Whittington, Douglas A
- Wu, Tian
- Zalameda, Leeanne
- Zhang, Nancy
- Tasker, Andrew S
- Hughes, Paul E
- Norman, Mark H
Producer: 20150723
In:
Bioorganic & medicinal chemistry letters vol. 24
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35.
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3-amino-7-phthalazinylbenzoisoxazoles as a novel class of potent, selective, and orally available inhibitors of p38alpha mitogen-activated protein kinase. [electronic resource] by
- Pettus, Liping H
- Xu, Shimin
- Cao, Guo-Qiang
- Chakrabarti, Partha P
- Rzasa, Robert M
- Sham, Kelvin
- Wurz, Ryan P
- Zhang, Dawei
- Middleton, Scott
- Henkle, Bradley
- Plant, Matthew H
- Saris, Christiaan J M
- Sherman, Lisa
- Wong, Lu Min
- Powers, David A
- Tudor, Yanyan
- Yu, Violeta
- Lee, Matthew R
- Syed, Rashid
- Hsieh, Faye
- Tasker, Andrew S
Producer: 20081113
In:
Journal of medicinal chemistry vol. 51
Availability: No items available.
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36.
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Discovery of highly selective and potent p38 inhibitors based on a phthalazine scaffold. [electronic resource] by
- Herberich, Brad
- Cao, Guo-Qiang
- Chakrabarti, Partha P
- Falsey, James R
- Pettus, Liping
- Rzasa, Robert M
- Reed, Anthony B
- Reichelt, Andreas
- Sham, Kelvin
- Thaman, Maya
- Wurz, Ryan P
- Xu, Shimin
- Zhang, Dawei
- Hsieh, Faye
- Lee, Matthew R
- Syed, Rashid
- Li, Vivian
- Grosfeld, David
- Plant, Matthew H
- Henkle, Bradley
- Sherman, Lisa
- Middleton, Scot
- Wong, Lu Min
- Tasker, Andrew S
Producer: 20081113
In:
Journal of medicinal chemistry vol. 51
Availability: No items available.
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37.
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Discovery of imidazopyridazines as potent Pim-1/2 kinase inhibitors. [electronic resource] by
- Wurz, Ryan P
- Sastri, Christine
- D'Amico, Derin C
- Herberich, Brad
- Jackson, Claire L M
- Pettus, Liping H
- Tasker, Andrew S
- Wu, Bin
- Guerrero, Nadia
- Lipford, J Russell
- Winston, Jeffrey T
- Yang, Yajing
- Wang, Paul
- Nguyen, Yen
- Andrews, Kristin L
- Huang, Xin
- Lee, Matthew R
- Mohr, Christopher
- Zhang, J D
- Reid, Darren L
- Xu, Yang
- Zhou, Yihong
- Wang, Hui-Ling
Producer: 20170626
In:
Bioorganic & medicinal chemistry letters vol. 26
Availability: No items available.
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38.
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Quinolinone-based agonists of S1P₁: use of a N-scan SAR strategy to optimize in vitro and in vivo activity. [electronic resource] by
- Pennington, Lewis D
- Croghan, Michael D
- Sham, Kelvin K C
- Pickrell, Alexander J
- Harrington, Paul E
- Frohn, Michael J
- Lanman, Brian A
- Reed, Anthony B
- Lee, Matthew R
- Xu, Han
- McElvain, Michele
- Xu, Yang
- Zhang, Xuxia
- Fiorino, Michael
- Horner, Michelle
- Morrison, Henry G
- Arnett, Heather A
- Fotsch, Christopher
- Tasker, Andrew S
- Wong, Min
- Cee, Victor J
Producer: 20120803
In:
Bioorganic & medicinal chemistry letters vol. 22
Availability: No items available.
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39.
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Design, synthesis, and biological evaluation of potent c-Met inhibitors. [electronic resource] by
- D'Angelo, Noel D
- Bellon, Steven F
- Booker, Shon K
- Cheng, Yuan
- Coxon, Angela
- Dominguez, Celia
- Fellows, Ingrid
- Hoffman, Douglas
- Hungate, Randall
- Kaplan-Lefko, Paula
- Lee, Matthew R
- Li, Chun
- Liu, Longbin
- Rainbeau, Elizabeth
- Reider, Paul J
- Rex, Karen
- Siegmund, Aaron
- Sun, Yaxiong
- Tasker, Andrew S
- Xi, Ning
- Xu, Shimin
- Yang, Yajing
- Zhang, Yihong
- Burgess, Teresa L
- Dussault, Isabelle
- Kim, Tae-Seong
Producer: 20081009
In:
Journal of medicinal chemistry vol. 51
Availability: No items available.
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40.
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The discovery of an orally efficacious positive allosteric modulator of the calcium sensing receptor containing a dibenzylamine core. [electronic resource] by
- Harrington, Paul E
- St Jean, David J
- Clarine, Jeffrey
- Coulter, Thomas S
- Croghan, Michael
- Davenport, Adam
- Davis, James
- Ghiron, Chiara
- Hutchinson, Jonathan
- Kelly, Michael G
- Lott, Fred
- Lu, Jenny Ying-Lin
- Martin, David
- Morony, Sean
- Poon, Steve F
- Portero-Larragueta, Elena
- Reagan, Jeff D
- Regal, Kelly A
- Tasker, Andrew
- Wang, Minghan
- Yang, Yuhua
- Yao, Guomin
- Zeng, Qingping
- Henley, Charles
- Fotsch, Christopher
Producer: 20101228
In:
Bioorganic & medicinal chemistry letters vol. 20
Availability: No items available.
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